ATE157970T1 - Dopamin-rezeptor-liganden und bilderzeugungsmittel - Google Patents
Dopamin-rezeptor-liganden und bilderzeugungsmittelInfo
- Publication number
- ATE157970T1 ATE157970T1 AT90302806T AT90302806T ATE157970T1 AT E157970 T1 ATE157970 T1 AT E157970T1 AT 90302806 T AT90302806 T AT 90302806T AT 90302806 T AT90302806 T AT 90302806T AT E157970 T1 ATE157970 T1 AT E157970T1
- Authority
- AT
- Austria
- Prior art keywords
- imaging agents
- receptor ligands
- dopamine receptor
- receptors
- epine
- Prior art date
Links
- 239000012216 imaging agent Substances 0.000 title abstract 2
- 102000015554 Dopamine receptor Human genes 0.000 title 1
- 108050004812 Dopamine receptor Proteins 0.000 title 1
- 239000003446 ligand Substances 0.000 title 1
- 210000004556 brain Anatomy 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 102000004076 Dopamine D1 Receptors Human genes 0.000 abstract 1
- 108090000511 Dopamine D1 Receptors Proteins 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 230000014759 maintenance of location Effects 0.000 abstract 1
- 102000005962 receptors Human genes 0.000 abstract 1
- 108020003175 receptors Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
- C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0468—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K51/047—Benzodiazepines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/22—Tin compounds
- C07F7/2208—Compounds having tin linked only to carbon, hydrogen and/or halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/332,625 US5068326A (en) | 1989-04-03 | 1989-04-03 | Dopamine receptor ligands and imaging agents |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE157970T1 true ATE157970T1 (de) | 1997-09-15 |
Family
ID=23299083
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT90302806T ATE157970T1 (de) | 1989-04-03 | 1990-03-15 | Dopamin-rezeptor-liganden und bilderzeugungsmittel |
Country Status (8)
Country | Link |
---|---|
US (1) | US5068326A (de) |
EP (1) | EP0391554B1 (de) |
JP (1) | JPH0660109B2 (de) |
KR (1) | KR930000148B1 (de) |
AT (1) | ATE157970T1 (de) |
AU (1) | AU620704B2 (de) |
CA (1) | CA2011738C (de) |
DE (1) | DE69031399D1 (de) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5320825A (en) * | 1991-05-01 | 1994-06-14 | Trustees Of The University Of Pennsylvania | Serotonin reuptake inhibitors for S.P.E.C.T. imaging |
US5446147A (en) * | 1992-04-03 | 1995-08-29 | Trustees Of The University Of Pennsylvania | Fluorinated and iodinated dopamine agents |
GB2271566A (en) * | 1992-10-14 | 1994-04-20 | Merck & Co Inc | HIV integrase inhibitors |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1561305A (en) * | 1975-07-02 | 1980-02-20 | Smithkline Corp | Benzazepine derivatives and pharmeceutical compositions containing them |
US4197297A (en) | 1976-11-17 | 1980-04-08 | Smithkline Corporation | 6-Halo-7,8-dihydroxy-1-(hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepines |
US4160765A (en) * | 1976-11-17 | 1979-07-10 | Smithkline Corporation | Method for 6-bromination of 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine compounds |
CH637383A5 (en) * | 1978-01-01 | 1983-07-29 | Smithkline Beckman Corp | Trisubstituted 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines, and their salts |
ZA882080B (en) * | 1987-03-27 | 1989-04-26 | Schering Corp | Substituted benzazepines,their preparation and pharmaceutical compositions containing them |
-
1989
- 1989-04-03 US US07/332,625 patent/US5068326A/en not_active Expired - Fee Related
-
1990
- 1990-03-08 CA CA002011738A patent/CA2011738C/en not_active Expired - Fee Related
- 1990-03-15 AT AT90302806T patent/ATE157970T1/de not_active IP Right Cessation
- 1990-03-15 EP EP90302806A patent/EP0391554B1/de not_active Expired - Lifetime
- 1990-03-15 DE DE69031399T patent/DE69031399D1/de not_active Expired - Lifetime
- 1990-03-27 AU AU52291/90A patent/AU620704B2/en not_active Ceased
- 1990-03-29 KR KR1019900004238A patent/KR930000148B1/ko not_active IP Right Cessation
- 1990-04-02 JP JP2085070A patent/JPH0660109B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA2011738C (en) | 1997-03-18 |
JPH0660109B2 (ja) | 1994-08-10 |
AU620704B2 (en) | 1992-02-20 |
DE69031399D1 (de) | 1997-10-16 |
KR900016139A (ko) | 1990-11-12 |
US5068326A (en) | 1991-11-26 |
JPH02286662A (ja) | 1990-11-26 |
CA2011738A1 (en) | 1990-10-03 |
EP0391554B1 (de) | 1997-09-10 |
AU5229190A (en) | 1990-10-04 |
KR930000148B1 (ko) | 1993-01-09 |
EP0391554A1 (de) | 1990-10-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |