ATE157370T1 - Oligonukleotide mit wirkung gegen das respiratorische synzytial virus - Google Patents
Oligonukleotide mit wirkung gegen das respiratorische synzytial virusInfo
- Publication number
- ATE157370T1 ATE157370T1 AT95911046T AT95911046T ATE157370T1 AT E157370 T1 ATE157370 T1 AT E157370T1 AT 95911046 T AT95911046 T AT 95911046T AT 95911046 T AT95911046 T AT 95911046T AT E157370 T1 ATE157370 T1 AT E157370T1
- Authority
- AT
- Austria
- Prior art keywords
- oligonucleotides
- respiratory
- virus
- synzytial
- active against
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1131—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Plant Pathology (AREA)
- Veterinary Medicine (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US19950394A | 1994-02-18 | 1994-02-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE157370T1 true ATE157370T1 (de) | 1997-09-15 |
Family
ID=22737804
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT95911046T ATE157370T1 (de) | 1994-02-18 | 1995-02-17 | Oligonukleotide mit wirkung gegen das respiratorische synzytial virus |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0745090B1 (de) |
JP (1) | JPH09509181A (de) |
AT (1) | ATE157370T1 (de) |
AU (1) | AU1878895A (de) |
CA (1) | CA2181546A1 (de) |
DE (1) | DE69500618D1 (de) |
WO (1) | WO1995022553A1 (de) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997014792A2 (en) * | 1995-10-17 | 1997-04-24 | Hybridon, Inc. | Oligonucleotides with anti-respiratory syncytial virus activity |
US6214805B1 (en) | 1996-02-15 | 2001-04-10 | The United States Of America As Represented By The Department Of Health And Human Services | RNase L activators and antisense oligonucleotides effective to treat RSV infections |
CA2246503A1 (en) * | 1996-02-15 | 1997-08-21 | National Institutes Of Health | Rnase l activators and antisense oligonucleotides effective to treat rsv infections |
US6958239B2 (en) | 1996-11-21 | 2005-10-25 | Oligos Etc Inc. | Three component chimeric antisense oligonucleotides |
US5831069A (en) * | 1997-03-04 | 1998-11-03 | South Alabama Medical Science Foundation | Antisense oligonucleotides against nonstructural proteins NS1 and NS2 of respiratory syncytial virus and uses thereof |
WO2003062258A1 (en) * | 2002-01-22 | 2003-07-31 | The Cleveland Clinic Foundation | Rnase l activator-antisense complexes |
EP3415625A1 (de) | 2002-02-01 | 2018-12-19 | Life Technologies Corporation | Doppelsträngige oligonukleotide |
CN104975020B (zh) | 2008-02-11 | 2020-01-17 | 菲奥医药公司 | 经修饰的RNAi多核苷酸及其用途 |
US10138485B2 (en) | 2008-09-22 | 2018-11-27 | Rxi Pharmaceuticals Corporation | Neutral nanotransporters |
WO2010090762A1 (en) | 2009-02-04 | 2010-08-12 | Rxi Pharmaceuticals Corporation | Rna duplexes with single stranded phosphorothioate nucleotide regions for additional functionality |
AU2011232365A1 (en) | 2010-03-24 | 2012-10-25 | Rxi Pharmaceuticals Corporation | RNA interference in dermal and fibrotic indications |
US9095504B2 (en) | 2010-03-24 | 2015-08-04 | Rxi Pharmaceuticals Corporation | RNA interference in ocular indications |
EP3077050B1 (de) | 2013-12-04 | 2020-10-21 | Phio Pharmaceuticals Corp. | Verfahren zur behandlung von wundheilung mit chemisch modifizierten oligonukleotiden |
WO2016037071A2 (en) | 2014-09-05 | 2016-03-10 | Rxi Pharmaceuticals Corporation | Methods for treating aging and skin disorders using nucleic acids targeting tyr or mmp1 |
US10808247B2 (en) | 2015-07-06 | 2020-10-20 | Phio Pharmaceuticals Corp. | Methods for treating neurological disorders using a synergistic small molecule and nucleic acids therapeutic approach |
WO2017007813A1 (en) | 2015-07-06 | 2017-01-12 | Rxi Pharmaceuticals Corporation | Nucleic acid molecules targeting superoxide dismutase 1 (sod1) |
WO2017070151A1 (en) | 2015-10-19 | 2017-04-27 | Rxi Pharmaceuticals Corporation | Reduced size self-delivering nucleic acid compounds targeting long non-coding rna |
WO2022103671A1 (en) * | 2020-11-12 | 2022-05-19 | Merck Sharp & Dohme Corp. | Anti-respiratory syncytial virus (rsv) antibody cell-based potency assay |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ244820A (en) * | 1991-10-25 | 1994-01-26 | Isis Pharmaceuticals Inc | Oligonucleotide inhibitor of epstein-barr virus. |
-
1995
- 1995-02-17 AU AU18788/95A patent/AU1878895A/en not_active Abandoned
- 1995-02-17 WO PCT/US1995/002080 patent/WO1995022553A1/en active IP Right Grant
- 1995-02-17 EP EP95911046A patent/EP0745090B1/de not_active Expired - Lifetime
- 1995-02-17 JP JP7521953A patent/JPH09509181A/ja active Pending
- 1995-02-17 AT AT95911046T patent/ATE157370T1/de not_active IP Right Cessation
- 1995-02-17 DE DE69500618T patent/DE69500618D1/de not_active Expired - Lifetime
- 1995-02-17 CA CA002181546A patent/CA2181546A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP0745090A1 (de) | 1996-12-04 |
JPH09509181A (ja) | 1997-09-16 |
AU1878895A (en) | 1995-09-04 |
EP0745090B1 (de) | 1997-08-27 |
DE69500618D1 (de) | 1997-10-02 |
CA2181546A1 (en) | 1995-08-24 |
WO1995022553A1 (en) | 1995-08-24 |
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Legal Events
Date | Code | Title | Description |
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RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |