ATE149166T1 - Alkali- und erdalkalisalze des oxipurinols in amorpher oder kristalliner form als mittel zur behandlung von hyperurikämie und gicht - Google Patents
Alkali- und erdalkalisalze des oxipurinols in amorpher oder kristalliner form als mittel zur behandlung von hyperurikämie und gichtInfo
- Publication number
- ATE149166T1 ATE149166T1 AT89913157T AT89913157T ATE149166T1 AT E149166 T1 ATE149166 T1 AT E149166T1 AT 89913157 T AT89913157 T AT 89913157T AT 89913157 T AT89913157 T AT 89913157T AT E149166 T1 ATE149166 T1 AT E149166T1
- Authority
- AT
- Austria
- Prior art keywords
- alkaline
- hyperuricemia
- gout
- crystalline form
- oxipurinol
- Prior art date
Links
- 201000001431 Hyperuricemia Diseases 0.000 title abstract 2
- HXNFUBHNUDHIGC-UHFFFAOYSA-N oxypurinol Chemical class O=C1NC(=O)N=C2NNC=C21 HXNFUBHNUDHIGC-UHFFFAOYSA-N 0.000 title abstract 2
- 229950002752 oxipurinol Drugs 0.000 title 1
- 201000005569 Gout Diseases 0.000 abstract 1
- 239000000654 additive Substances 0.000 abstract 1
- 239000003513 alkali Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3839826A DE3839826A1 (de) | 1988-11-25 | 1988-11-25 | Alkali- und erdalkalisalze des oxipurinols in amorpher oder kristalliner form als mittel zur behandlung von hyperurikaemie und gicht |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE149166T1 true ATE149166T1 (de) | 1997-03-15 |
Family
ID=6367882
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT89913157T ATE149166T1 (de) | 1988-11-25 | 1989-11-24 | Alkali- und erdalkalisalze des oxipurinols in amorpher oder kristalliner form als mittel zur behandlung von hyperurikämie und gicht |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0593418B1 (enrdf_load_html_response) |
JP (1) | JP2772717B2 (enrdf_load_html_response) |
AT (1) | ATE149166T1 (enrdf_load_html_response) |
DE (2) | DE3839826A1 (enrdf_load_html_response) |
WO (1) | WO1990006313A2 (enrdf_load_html_response) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH05501563A (ja) * | 1989-11-18 | 1993-03-25 | シエーリング・アグロケミカルズ・リミテツド | プロペン酸誘導体の製造 |
DE19920775A1 (de) * | 1999-05-05 | 2000-11-16 | Isis Pharma Gmbh | Arzneistoffverwendung zur Vermeidung von Nitrattoleranz |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB975850A (en) * | 1955-08-10 | 1964-11-18 | Wellcome Found | Xanthine oxidase inhibitors |
US3624205A (en) * | 1967-04-25 | 1971-11-30 | Burroughs Wellcome Co | Treatment of hyperuricemia in humans |
GB2187954B (en) * | 1986-03-13 | 1990-05-02 | Wellcome Found | Oxypurinol for use in cell protection. |
AU598239B2 (en) * | 1986-03-13 | 1990-06-21 | Wellcome Foundation Limited, The | The application of tissue plasminogen activator and oxypurinol in dissolving blood clots and in preventing damage to ischaemic tissue during reperfusion |
-
1988
- 1988-11-25 DE DE3839826A patent/DE3839826A1/de active Granted
-
1989
- 1989-11-24 JP JP2500186A patent/JP2772717B2/ja not_active Expired - Lifetime
- 1989-11-24 WO PCT/EP1989/001424 patent/WO1990006313A2/de active IP Right Grant
- 1989-11-24 AT AT89913157T patent/ATE149166T1/de not_active IP Right Cessation
- 1989-11-24 DE DE58909779T patent/DE58909779D1/de not_active Expired - Lifetime
- 1989-11-24 EP EP89913157A patent/EP0593418B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JP2772717B2 (ja) | 1998-07-09 |
WO1990006313A3 (de) | 1990-08-23 |
EP0593418B1 (de) | 1997-02-26 |
DE3839826A1 (de) | 1990-05-31 |
WO1990006313A2 (de) | 1990-06-14 |
DE58909779D1 (de) | 1997-04-03 |
EP0593418A1 (de) | 1994-04-27 |
DE3839826C2 (enrdf_load_html_response) | 1993-05-27 |
JPH04502003A (ja) | 1992-04-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EELA | Cancelled due to lapse of time |