ATE141165T1 - Verwendung von 4-mercapto-6-hydroxy-pyrazolo(4,3- d)-pyrimidine als radikalfänger - Google Patents
Verwendung von 4-mercapto-6-hydroxy-pyrazolo(4,3- d)-pyrimidine als radikalfängerInfo
- Publication number
- ATE141165T1 ATE141165T1 AT90400081T AT90400081T ATE141165T1 AT E141165 T1 ATE141165 T1 AT E141165T1 AT 90400081 T AT90400081 T AT 90400081T AT 90400081 T AT90400081 T AT 90400081T AT E141165 T1 ATE141165 T1 AT E141165T1
- Authority
- AT
- Austria
- Prior art keywords
- mercapto
- pyrimidine
- pyrazolo
- hydroxy
- caugger
- Prior art date
Links
- PNXMRBSRQDZZFU-UHFFFAOYSA-N 6-hydroxy-4-sulfanyl-5h-pyrazolo[4,3-d]pyrimidine Chemical compound ON1CN(S)C2=CN=NC2=C1 PNXMRBSRQDZZFU-UHFFFAOYSA-N 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 206010002660 Anoxia Diseases 0.000 abstract 1
- 241000976983 Anoxia Species 0.000 abstract 1
- 206010021143 Hypoxia Diseases 0.000 abstract 1
- 230000007953 anoxia Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 208000028867 ischemia Diseases 0.000 abstract 1
- 239000002516 radical scavenger Substances 0.000 abstract 1
- 210000002345 respiratory system Anatomy 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 230000002792 vascular Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8900353A FR2641465A1 (fr) | 1989-01-11 | 1989-01-11 | Nouveau capteur de radicaux libres et les compositions pharmaceutiques en contenant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE141165T1 true ATE141165T1 (de) | 1996-08-15 |
Family
ID=9377685
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90400081T ATE141165T1 (de) | 1989-01-11 | 1990-01-11 | Verwendung von 4-mercapto-6-hydroxy-pyrazolo(4,3- d)-pyrimidine als radikalfänger |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP0378483B1 (de) |
| AT (1) | ATE141165T1 (de) |
| DE (1) | DE69028024D1 (de) |
| FR (1) | FR2641465A1 (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1251838B (it) * | 1991-09-20 | 1995-05-26 | Lpb Ist Farm | Uso della nimesulide nel trattamento della cataratta |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3141M (fr) * | 1962-05-23 | 1965-02-22 | Wellcome Found | Médicament a base d'un dérivé de pyrazolo [3.4-d] pyrimidine. |
| US3474098A (en) * | 1968-08-22 | 1969-10-21 | Burroughs Wellcome Co | Pyrazolo-(3,4-d) pyrimidines |
| ZA871813B (en) * | 1986-03-13 | 1988-10-26 | Wellcome Found | Cell protection |
| FR2608045B1 (fr) * | 1986-12-12 | 1990-03-02 | Chauvin Laboratoires | Utilisation d'inhibiteurs de xanthine- oxydase, de piegeurs de radicaux libres oxygenes et de chelateurs du fer pour la fabrication d'une composition pharmaceutique destinee au traitement du glaucome et compositions pharmaceutiques destinees au traitement du glaucome |
-
1989
- 1989-01-11 FR FR8900353A patent/FR2641465A1/fr active Pending
-
1990
- 1990-01-11 AT AT90400081T patent/ATE141165T1/de not_active IP Right Cessation
- 1990-01-11 DE DE69028024T patent/DE69028024D1/de not_active Expired - Lifetime
- 1990-01-11 EP EP90400081A patent/EP0378483B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0378483A2 (de) | 1990-07-18 |
| EP0378483B1 (de) | 1996-08-14 |
| DE69028024D1 (de) | 1996-09-19 |
| EP0378483A3 (de) | 1991-09-11 |
| FR2641465A1 (fr) | 1990-07-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |