ATE136223T1 - Perfluoro-t-butyl enthaltende verbindungen zur verwendung in fluor-19-nmr und/oder mri - Google Patents

Perfluoro-t-butyl enthaltende verbindungen zur verwendung in fluor-19-nmr und/oder mri

Info

Publication number
ATE136223T1
ATE136223T1 AT90912277T AT90912277T ATE136223T1 AT E136223 T1 ATE136223 T1 AT E136223T1 AT 90912277 T AT90912277 T AT 90912277T AT 90912277 T AT90912277 T AT 90912277T AT E136223 T1 ATE136223 T1 AT E136223T1
Authority
AT
Austria
Prior art keywords
moiety
fluorine
mri
perfluoro
nmr
Prior art date
Application number
AT90912277T
Other languages
English (en)
Inventor
Walter John Rogers Jr
Thomas Stephen Everett
Original Assignee
Univ Johns Hopkins
Univ State Towson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Johns Hopkins, Univ State Towson filed Critical Univ Johns Hopkins
Application granted granted Critical
Publication of ATE136223T1 publication Critical patent/ATE136223T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/806—Electrical property or magnetic property
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
AT90912277T 1989-07-31 1990-07-19 Perfluoro-t-butyl enthaltende verbindungen zur verwendung in fluor-19-nmr und/oder mri ATE136223T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/388,049 US5116599A (en) 1989-07-31 1989-07-31 Perfluoro-t-butyl-containing compounds for use in fluorine-19 nmr and/or mri

Publications (1)

Publication Number Publication Date
ATE136223T1 true ATE136223T1 (de) 1996-04-15

Family

ID=23532431

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90912277T ATE136223T1 (de) 1989-07-31 1990-07-19 Perfluoro-t-butyl enthaltende verbindungen zur verwendung in fluor-19-nmr und/oder mri

Country Status (10)

Country Link
US (3) US5116599A (de)
EP (1) EP0485479B1 (de)
JP (1) JPH05501869A (de)
AT (1) ATE136223T1 (de)
AU (1) AU651559B2 (de)
CA (1) CA2064567A1 (de)
DE (1) DE69026384T2 (de)
DK (1) DK0485479T3 (de)
ES (1) ES2087161T3 (de)
WO (1) WO1991001759A1 (de)

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US5362478A (en) * 1993-03-26 1994-11-08 Vivorx Pharmaceuticals, Inc. Magnetic resonance imaging with fluorocarbons encapsulated in a cross-linked polymeric shell
US5665382A (en) * 1993-02-22 1997-09-09 Vivorx Pharmaceuticals, Inc. Methods for the preparation of pharmaceutically active agents for in vivo delivery
US6753006B1 (en) 1993-02-22 2004-06-22 American Bioscience, Inc. Paclitaxel-containing formulations
US5650156A (en) * 1993-02-22 1997-07-22 Vivorx Pharmaceuticals, Inc. Methods for in vivo delivery of nutriceuticals and compositions useful therefor
US20030133955A1 (en) * 1993-02-22 2003-07-17 American Bioscience, Inc. Methods and compositions useful for administration of chemotherapeutic agents
US20030068362A1 (en) * 1993-02-22 2003-04-10 American Bioscience, Inc. Methods and formulations for the delivery of pharmacologically active agents
US5401493A (en) * 1993-03-26 1995-03-28 Molecular Biosystems, Inc. Perfluoro-1H,-1H-neopentyl containing contrast agents and method to use same
US5851510A (en) * 1994-05-16 1998-12-22 The Board Of Regents Of The University Of Michigan Hepatocyte-selective oil-in-water emulsion
US6645463B1 (en) 1994-05-16 2003-11-11 The Board Of Regents Of The University Of Michigan Blood-pool selective carrier for lipophilic imaging agents
WO1998053855A1 (en) 1997-05-30 1998-12-03 Alliance Pharmaceutical Corp. Methods and apparatus for monitoring and quantifying the movement of fluid
US5622687A (en) * 1994-11-15 1997-04-22 Molecular Biosystems, Inc. Calixarene conjugates useful as MRI and CT diagnostic imaging agents
US5660815A (en) * 1995-04-28 1997-08-26 Molecular Biosystems, Inc. Water soluble fluorinated fatty acid sulfonate derivatives useful as magnetic resonance imaging agents
FR2736051B3 (fr) * 1995-06-29 1997-09-26 Guerbet Sa Complexes metalliques de polyaminoacides, leur procede de preparation et leur utilisation en imagerie diagnostique
US5808146A (en) * 1995-11-09 1998-09-15 Emory University Amino acid analogs for tumor imaging
DE19719280C1 (de) * 1997-05-07 1998-09-24 Pharm Pur Gmbh Fluorierte Alkane und ihre Verwendungen
WO2001039664A1 (en) * 1999-12-02 2001-06-07 The General Hospital Corporation Method and apparatus for measuring indices of brain activity
US6907280B2 (en) * 1999-12-02 2005-06-14 The General Hospital Corporation Method and apparatus for objectively measuring pain, pain treatment and other related techniques
US6574497B1 (en) 2000-12-22 2003-06-03 Advanced Cardiovascular Systems, Inc. MRI medical device markers utilizing fluorine-19
US20030054042A1 (en) * 2001-09-14 2003-03-20 Elaine Liversidge Stabilization of chemical compounds using nanoparticulate formulations
US20080220075A1 (en) * 2002-03-20 2008-09-11 Elan Pharma International Ltd. Nanoparticulate compositions of angiogenesis inhibitors
CA2479665C (en) * 2002-03-20 2011-08-30 Elan Pharma International Ltd. Nanoparticulate compositions of angiogenesis inhibitors
JP2005531648A (ja) * 2002-04-11 2005-10-20 カルボマー インク 生体適合性物質およびプローブ類
DE60333830D1 (de) * 2002-04-30 2010-09-30 Univ Emory Verbindungen zur abbildung von tumoren
CA2586111A1 (en) * 2004-11-12 2006-06-08 Neurochem (International) Limited Methods and fluorinated compositions for treating amyloid-related diseases
TWI265916B (en) * 2004-12-31 2006-11-11 Ind Tech Res Inst Process of making YAG fluorescence powder
AU2006204045B2 (en) * 2005-01-05 2010-10-14 Board Of Regents, The University Of Texas System Conjugates for dual imaging and radiochemotherapy: composition, manufacturing, and applications
WO2006096499A2 (en) * 2005-03-04 2006-09-14 Washington University Mr coronary angiography with a fluorinated nanoparticle contrast agent at 1.5 t
JP5349960B2 (ja) * 2005-06-23 2013-11-20 エモリー ユニバーシティー 腫瘍画像化のためのアミノ酸類似体の立体選択的合成
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Also Published As

Publication number Publication date
US5324504A (en) 1994-06-28
ES2087161T3 (es) 1996-07-16
AU6164590A (en) 1991-03-11
DE69026384D1 (de) 1996-05-09
CA2064567A1 (en) 1991-02-01
EP0485479B1 (de) 1996-04-03
WO1991001759A1 (en) 1991-02-21
EP0485479A1 (de) 1992-05-20
AU651559B2 (en) 1994-07-28
US5116599A (en) 1992-05-26
US5397563A (en) 1995-03-14
DK0485479T3 (da) 1996-05-13
DE69026384T2 (de) 1996-08-08
JPH05501869A (ja) 1993-04-08

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee