ATE135002T1 - Wasserlösliche derivate von taxol mit antineoplastischer aktivität - Google Patents

Wasserlösliche derivate von taxol mit antineoplastischer aktivität

Info

Publication number
ATE135002T1
ATE135002T1 AT92308421T AT92308421T ATE135002T1 AT E135002 T1 ATE135002 T1 AT E135002T1 AT 92308421 T AT92308421 T AT 92308421T AT 92308421 T AT92308421 T AT 92308421T AT E135002 T1 ATE135002 T1 AT E135002T1
Authority
AT
Austria
Prior art keywords
taxol
cyz
synthesized
group
reacting
Prior art date
Application number
AT92308421T
Other languages
English (en)
Inventor
David G I Kingston
State Uni Inst
Zhi-Yang Zhao
Uni State
Original Assignee
Virginia Tech Intell Prop
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Virginia Tech Intell Prop filed Critical Virginia Tech Intell Prop
Application granted granted Critical
Publication of ATE135002T1 publication Critical patent/ATE135002T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT92308421T 1991-10-15 1992-09-16 Wasserlösliche derivate von taxol mit antineoplastischer aktivität ATE135002T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/774,107 US5278324A (en) 1990-08-28 1991-10-15 Water soluble derivatives of taxol

Publications (1)

Publication Number Publication Date
ATE135002T1 true ATE135002T1 (de) 1996-03-15

Family

ID=25100263

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92308421T ATE135002T1 (de) 1991-10-15 1992-09-16 Wasserlösliche derivate von taxol mit antineoplastischer aktivität

Country Status (13)

Country Link
US (1) US5278324A (de)
EP (1) EP0537905B1 (de)
KR (1) KR930007925A (de)
AT (1) ATE135002T1 (de)
CA (1) CA2080393A1 (de)
CZ (1) CZ312292A3 (de)
DE (1) DE69208802T2 (de)
DK (1) DK0537905T3 (de)
ES (1) ES2086669T3 (de)
FI (1) FI924678A7 (de)
GR (1) GR3020109T3 (de)
NZ (1) NZ244754A (de)
PL (2) PL296256A1 (de)

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US6576636B2 (en) * 1996-05-22 2003-06-10 Protarga, Inc. Method of treating a liver disorder with fatty acid-antiviral agent conjugates
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GB9705903D0 (en) 1997-03-21 1997-05-07 Elliott Gillian D VP22 Proteins and uses thereof
US7235583B1 (en) * 1999-03-09 2007-06-26 Luitpold Pharmaceuticals, Inc., Fatty acid-anticancer conjugates and uses thereof
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US20030157170A1 (en) * 2001-03-13 2003-08-21 Richard Liggins Micellar drug delivery vehicles and precursors thereto and uses thereof
WO2002076404A2 (en) * 2001-03-23 2002-10-03 Protarga, Inc. Fatty alcohol drug conjugates
AU2002303164A1 (en) 2001-03-23 2002-10-08 Protarga, Inc. Fatty amine drug conjugates
DK1392254T3 (da) * 2001-04-20 2007-07-02 Univ British Columbia Micelle-lægemiddelindgivelsessystem for hydrofobe lægemidler
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US20030216758A1 (en) * 2001-12-28 2003-11-20 Angiotech Pharmaceuticals, Inc. Coated surgical patches
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US20070010702A1 (en) * 2003-04-08 2007-01-11 Xingwu Wang Medical device with low magnetic susceptibility
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US20070149496A1 (en) * 2003-10-31 2007-06-28 Jack Tuszynski Water-soluble compound
US7622453B2 (en) 2003-12-23 2009-11-24 Santaris Pharma A/S Oligomeric compounds for the modulation of Bcl-2
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US7989490B2 (en) * 2004-06-02 2011-08-02 Cordis Corporation Injectable formulations of taxanes for cad treatment
US7846940B2 (en) * 2004-03-31 2010-12-07 Cordis Corporation Solution formulations of sirolimus and its analogs for CAD treatment
US8003122B2 (en) 2004-03-31 2011-08-23 Cordis Corporation Device for local and/or regional delivery employing liquid formulations of therapeutic agents
US9447138B2 (en) 2004-11-09 2016-09-20 Roche Innovation Center Copenhagen A/S Potent LNA oligonucleotides for the inhibition of HIF-1a expression
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US20070073385A1 (en) * 2005-09-20 2007-03-29 Cook Incorporated Eluting, implantable medical device
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US20080241215A1 (en) * 2007-03-28 2008-10-02 Robert Falotico Local vascular delivery of probucol alone or in combination with sirolimus to treat restenosis, vulnerable plaque, aaa and stroke
EP2278963A4 (de) * 2008-01-16 2014-09-17 Anwar Rayan Derivate von taxol und eng verwandte verbindungen
US8420110B2 (en) 2008-03-31 2013-04-16 Cordis Corporation Drug coated expandable devices
US8409601B2 (en) 2008-03-31 2013-04-02 Cordis Corporation Rapamycin coated expandable devices
US8273404B2 (en) * 2008-05-19 2012-09-25 Cordis Corporation Extraction of solvents from drug containing polymer reservoirs
US8642063B2 (en) * 2008-08-22 2014-02-04 Cook Medical Technologies Llc Implantable medical device coatings with biodegradable elastomer and releasable taxane agent
US9198968B2 (en) 2008-09-15 2015-12-01 The Spectranetics Corporation Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens
US8802394B2 (en) 2008-11-13 2014-08-12 Radu O. Minea Method of expressing proteins with disulfide bridges with enhanced yields and activity
US20120303115A1 (en) 2011-05-25 2012-11-29 Dadino Ronald C Expandable devices coated with a rapamycin composition
US20120302954A1 (en) 2011-05-25 2012-11-29 Zhao Jonathon Z Expandable devices coated with a paclitaxel composition
US9956385B2 (en) 2012-06-28 2018-05-01 The Spectranetics Corporation Post-processing of a medical device to control morphology and mechanical properties
KR20220025946A (ko) 2014-03-21 2022-03-03 애브비 인코포레이티드 항-ｅｇｆｒ 항체 및 항체 약물 접합체
US10517961B2 (en) 2015-09-25 2019-12-31 ZY Therapeutics, Inc. Drug formulation based on particulates comprising polysaccharide-vitamin conjugate
EP3835322A3 (de) 2016-06-08 2021-10-06 AbbVie Inc. Anti-b7-h3-antikörper und antikörperarzneimittelkonjugate
CN109562169A (zh) 2016-06-08 2019-04-02 艾伯维公司 抗cd98抗体及抗体药物偶联物
WO2017214322A1 (en) 2016-06-08 2017-12-14 Abbvie Inc. Anti-b7-h3 antibodies and antibody drug conjugates
CN109562168A (zh) 2016-06-08 2019-04-02 艾伯维公司 抗cd98抗体及抗体药物偶联物
EP3469000A1 (de) 2016-06-08 2019-04-17 AbbVie Inc. Anti-b7-h3-antikörper und antikörperarzneimittelkonjugate
AR124681A1 (es) 2021-01-20 2023-04-26 Abbvie Inc Conjugados anticuerpo-fármaco anti-egfr

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4942184A (en) * 1988-03-07 1990-07-17 The United States Of America As Represented By The Department Of Health And Human Services Water soluble, antineoplastic derivatives of taxol
US5059699A (en) * 1990-08-28 1991-10-22 Virginia Tech Intellectual Properties, Inc. Water soluble derivatives of taxol

Also Published As

Publication number Publication date
DE69208802D1 (de) 1996-04-11
CA2080393A1 (en) 1993-04-16
EP0537905B1 (de) 1996-03-06
KR930007925A (ko) 1993-05-20
PL296256A1 (en) 1993-10-18
ES2086669T3 (es) 1996-07-01
FI924678A0 (fi) 1992-10-15
PL299303A1 (en) 1994-01-10
US5278324A (en) 1994-01-11
DK0537905T3 (da) 1996-07-22
GR3020109T3 (en) 1996-08-31
DE69208802T2 (de) 1996-10-02
EP0537905A1 (de) 1993-04-21
FI924678L (fi) 1993-04-16
CZ312292A3 (en) 1993-05-12
NZ244754A (en) 1995-03-28
FI924678A7 (fi) 1993-04-16

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee