ATE127017T1 - Castanosperminester zur behandlung der zerebralen malaria. - Google Patents
Castanosperminester zur behandlung der zerebralen malaria.Info
- Publication number
- ATE127017T1 ATE127017T1 AT90119842T AT90119842T ATE127017T1 AT E127017 T1 ATE127017 T1 AT E127017T1 AT 90119842 T AT90119842 T AT 90119842T AT 90119842 T AT90119842 T AT 90119842T AT E127017 T1 ATE127017 T1 AT E127017T1
- Authority
- AT
- Austria
- Prior art keywords
- treatment
- cells
- falciparum
- cause
- cerebral malaria
- Prior art date
Links
- 206010063094 Cerebral malaria Diseases 0.000 title 1
- DWBDMLGCCJIACZ-ODXJTPSBSA-N [(1s,6s,7s,8r,8ar)-1,7,8-trihydroxy-1,2,3,5,6,7,8,8a-octahydroindolizin-6-yl] benzoate Chemical compound O([C@H]1CN2CC[C@@H]([C@@H]2[C@@H](O)[C@@H]1O)O)C(=O)C1=CC=CC=C1 DWBDMLGCCJIACZ-ODXJTPSBSA-N 0.000 title 1
- 241000223960 Plasmodium falciparum Species 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 2
- 230000002792 vascular Effects 0.000 abstract 2
- JDVVGAQPNNXQDW-WCMLQCRESA-N Castanospermine Natural products O[C@H]1[C@@H](O)[C@H]2[C@@H](O)CCN2C[C@H]1O JDVVGAQPNNXQDW-WCMLQCRESA-N 0.000 abstract 1
- JDVVGAQPNNXQDW-TVNFTVLESA-N Castinospermine Chemical compound C1[C@H](O)[C@@H](O)[C@H](O)[C@H]2[C@@H](O)CCN21 JDVVGAQPNNXQDW-TVNFTVLESA-N 0.000 abstract 1
- 210000000601 blood cell Anatomy 0.000 abstract 1
- 230000017531 blood circulation Effects 0.000 abstract 1
- 230000002490 cerebral effect Effects 0.000 abstract 1
- 230000003511 endothelial effect Effects 0.000 abstract 1
- 210000003743 erythrocyte Anatomy 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 210000004185 liver Anatomy 0.000 abstract 1
- 201000004792 malaria Diseases 0.000 abstract 1
- 244000045947 parasite Species 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
- A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US42286989A | 1989-10-17 | 1989-10-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE127017T1 true ATE127017T1 (de) | 1995-09-15 |
Family
ID=23676762
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT90119842T ATE127017T1 (de) | 1989-10-17 | 1990-10-16 | Castanosperminester zur behandlung der zerebralen malaria. |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0423728B1 (de) |
JP (1) | JPH03133930A (de) |
KR (1) | KR100188799B1 (de) |
AT (1) | ATE127017T1 (de) |
AU (1) | AU628228B2 (de) |
DE (1) | DE69021980T2 (de) |
IE (1) | IE67048B1 (de) |
ZA (1) | ZA908134B (de) |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1315276C (en) * | 1987-07-02 | 1993-03-30 | Paul S. Liu | Castanospermine esters and glycosides |
US5004746A (en) * | 1987-09-29 | 1991-04-02 | Merrell Dow Pharmaceuticals Inc. | Anti-retroviral castanospermine esters |
AU618838B2 (en) * | 1988-08-10 | 1992-01-09 | Praxis Pharmaceuticals, Inc. | Use of castanospermine as an anti-inflammatory and immunosuppressant agent |
-
1990
- 1990-10-11 ZA ZA908134A patent/ZA908134B/xx unknown
- 1990-10-11 AU AU64532/90A patent/AU628228B2/en not_active Ceased
- 1990-10-16 JP JP2275495A patent/JPH03133930A/ja active Pending
- 1990-10-16 KR KR1019900016431A patent/KR100188799B1/ko not_active IP Right Cessation
- 1990-10-16 IE IE371190A patent/IE67048B1/en not_active IP Right Cessation
- 1990-10-16 AT AT90119842T patent/ATE127017T1/de not_active IP Right Cessation
- 1990-10-16 EP EP90119842A patent/EP0423728B1/de not_active Expired - Lifetime
- 1990-10-16 DE DE69021980T patent/DE69021980T2/de not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ZA908134B (en) | 1991-07-31 |
DE69021980T2 (de) | 1996-02-15 |
KR910007529A (ko) | 1991-05-30 |
EP0423728A2 (de) | 1991-04-24 |
IE903711A1 (en) | 1991-04-24 |
IE67048B1 (en) | 1996-02-21 |
AU6453290A (en) | 1991-04-26 |
JPH03133930A (ja) | 1991-06-07 |
DE69021980D1 (de) | 1995-10-05 |
AU628228B2 (en) | 1992-09-10 |
EP0423728B1 (de) | 1995-08-30 |
EP0423728A3 (en) | 1993-02-03 |
KR100188799B1 (ko) | 1999-06-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |