ATE111446T1 - Cyanoguanidin-derivate. - Google Patents
Cyanoguanidin-derivate.Info
- Publication number
- ATE111446T1 ATE111446T1 AT90112296T AT90112296T ATE111446T1 AT E111446 T1 ATE111446 T1 AT E111446T1 AT 90112296 T AT90112296 T AT 90112296T AT 90112296 T AT90112296 T AT 90112296T AT E111446 T1 ATE111446 T1 AT E111446T1
- Authority
- AT
- Austria
- Prior art keywords
- cyanoguanidine derivatives
- cyanoguanidine
- derivatives
- chem
- chlorine
- Prior art date
Links
- QGBSISYHAICWAH-UHFFFAOYSA-N dicyandiamide Chemical class NC(N)=NC#N QGBSISYHAICWAH-UHFFFAOYSA-N 0.000 title 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- 239000002220 antihypertensive agent Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003218 coronary vasodilator agent Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/28—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to cyano groups, e.g. cyanoguanidines, dicyandiamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Cardiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1166119A JP2749639B2 (ja) | 1989-06-28 | 1989-06-28 | シアノグアニジン誘導体 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE111446T1 true ATE111446T1 (de) | 1994-09-15 |
Family
ID=15825385
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90112296T ATE111446T1 (de) | 1989-06-28 | 1990-06-27 | Cyanoguanidin-derivate. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5087640A (de) |
| EP (1) | EP0405525B1 (de) |
| JP (1) | JP2749639B2 (de) |
| KR (1) | KR910000629A (de) |
| AT (1) | ATE111446T1 (de) |
| DE (1) | DE69012451T2 (de) |
| DK (1) | DK0405525T3 (de) |
| ES (1) | ES2059901T3 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5525742A (en) * | 1994-06-10 | 1996-06-11 | The Upjohn Company | Azidophenylcyanoguanidines as photoaffinity probes |
| US5856449A (en) * | 1994-11-17 | 1999-01-05 | Pharmacia & Upjohn Company | Protein affecting KATP channels |
| US6147098A (en) * | 1998-05-11 | 2000-11-14 | Novo Nordisk A/S | Substituted guanidines and diaminonitroethenes, their preparation and use |
| WO1999058497A1 (en) * | 1998-05-11 | 1999-11-18 | Novo Nordisk A/S | Substituted guanidines and diaminonitroethenes, their preparation and use |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2479498A (en) * | 1946-08-08 | 1949-08-16 | American Cyanamid Co | Preparation of 1,2-disubstituted-3-cyanoguanidines |
| DE1542792B2 (de) * | 1965-11-09 | 1974-08-01 | Bayer Ag, 5090 Leverkusen | Verwendung von Monoarylguanidinen zur Abwehr von Vögeln, Nagetieren und hasenartigen Tieren |
| DE3014353A1 (de) * | 1980-04-15 | 1982-01-21 | Bayer Ag, 5090 Leverkusen | Trisubstituierte cyanguanidine, verfahren zu ihrer herstellung sowie ihre verwendung als fungizide |
| EP0113070B1 (de) * | 1982-12-20 | 1988-01-13 | American Cyanamid Company | Verwendung substituierter Nitro- und Cyanoguanidine zur Erhöhung der Ernteerträge |
| US4804780A (en) * | 1982-12-20 | 1989-02-14 | American Cyanamid Company | Substituted nitro and cyanoguanidines |
| US4639268A (en) * | 1985-07-29 | 1987-01-27 | American Cyanamid Company | Nitro- and cyanoguanidines as selective preemergence herbicides and plant defoliants |
| EP0310545A3 (de) * | 1987-09-02 | 1989-07-26 | Ciba-Geigy Ag | Cyanoguanidine als Härter für Epoxidharze |
| US5011837A (en) * | 1988-08-09 | 1991-04-30 | E. R. Squibb & Sons, Inc. | Aryl cyanoguanidines: potassium channel activators and method of making same |
| GB8908063D0 (en) * | 1989-04-11 | 1989-05-24 | Beecham Group Plc | Novel compounds |
-
1989
- 1989-06-28 JP JP1166119A patent/JP2749639B2/ja not_active Expired - Fee Related
-
1990
- 1990-06-27 EP EP90112296A patent/EP0405525B1/de not_active Expired - Lifetime
- 1990-06-27 DK DK90112296.0T patent/DK0405525T3/da active
- 1990-06-27 AT AT90112296T patent/ATE111446T1/de not_active IP Right Cessation
- 1990-06-27 ES ES90112296T patent/ES2059901T3/es not_active Expired - Lifetime
- 1990-06-27 US US07/544,448 patent/US5087640A/en not_active Expired - Fee Related
- 1990-06-27 DE DE69012451T patent/DE69012451T2/de not_active Expired - Fee Related
- 1990-06-28 KR KR1019900009642A patent/KR910000629A/ko not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0331250A (ja) | 1991-02-12 |
| EP0405525B1 (de) | 1994-09-14 |
| ES2059901T3 (es) | 1994-11-16 |
| EP0405525A3 (en) | 1992-03-25 |
| DE69012451T2 (de) | 1995-02-02 |
| DE69012451D1 (de) | 1994-10-20 |
| EP0405525A2 (de) | 1991-01-02 |
| US5087640A (en) | 1992-02-11 |
| DK0405525T3 (da) | 1994-10-17 |
| KR910000629A (ko) | 1991-01-29 |
| JP2749639B2 (ja) | 1998-05-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |