ATE111446T1 - Cyanoguanidin-derivate. - Google Patents

Cyanoguanidin-derivate.

Info

Publication number
ATE111446T1
ATE111446T1 AT90112296T AT90112296T ATE111446T1 AT E111446 T1 ATE111446 T1 AT E111446T1 AT 90112296 T AT90112296 T AT 90112296T AT 90112296 T AT90112296 T AT 90112296T AT E111446 T1 ATE111446 T1 AT E111446T1
Authority
AT
Austria
Prior art keywords
cyanoguanidine derivatives
cyanoguanidine
derivatives
chem
chlorine
Prior art date
Application number
AT90112296T
Other languages
English (en)
Inventor
Tominori Morita
Kazuya Yoshiizumi
Noriyasu Nishimura
Katsumi Goto
Takayuki Sukamoto
Kohichiro Yoshino
Original Assignee
Kanebo Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kanebo Ltd filed Critical Kanebo Ltd
Application granted granted Critical
Publication of ATE111446T1 publication Critical patent/ATE111446T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/28—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to cyano groups, e.g. cyanoguanidines, dicyandiamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT90112296T 1989-06-28 1990-06-27 Cyanoguanidin-derivate. ATE111446T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1166119A JP2749639B2 (ja) 1989-06-28 1989-06-28 シアノグアニジン誘導体

Publications (1)

Publication Number Publication Date
ATE111446T1 true ATE111446T1 (de) 1994-09-15

Family

ID=15825385

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90112296T ATE111446T1 (de) 1989-06-28 1990-06-27 Cyanoguanidin-derivate.

Country Status (8)

Country Link
US (1) US5087640A (de)
EP (1) EP0405525B1 (de)
JP (1) JP2749639B2 (de)
KR (1) KR910000629A (de)
AT (1) ATE111446T1 (de)
DE (1) DE69012451T2 (de)
DK (1) DK0405525T3 (de)
ES (1) ES2059901T3 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5525742A (en) * 1994-06-10 1996-06-11 The Upjohn Company Azidophenylcyanoguanidines as photoaffinity probes
US5856449A (en) * 1994-11-17 1999-01-05 Pharmacia & Upjohn Company Protein affecting KATP channels
US6147098A (en) * 1998-05-11 2000-11-14 Novo Nordisk A/S Substituted guanidines and diaminonitroethenes, their preparation and use
WO1999058497A1 (en) * 1998-05-11 1999-11-18 Novo Nordisk A/S Substituted guanidines and diaminonitroethenes, their preparation and use

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2479498A (en) * 1946-08-08 1949-08-16 American Cyanamid Co Preparation of 1,2-disubstituted-3-cyanoguanidines
DE1542792B2 (de) * 1965-11-09 1974-08-01 Bayer Ag, 5090 Leverkusen Verwendung von Monoarylguanidinen zur Abwehr von Vögeln, Nagetieren und hasenartigen Tieren
DE3014353A1 (de) * 1980-04-15 1982-01-21 Bayer Ag, 5090 Leverkusen Trisubstituierte cyanguanidine, verfahren zu ihrer herstellung sowie ihre verwendung als fungizide
US4804780A (en) * 1982-12-20 1989-02-14 American Cyanamid Company Substituted nitro and cyanoguanidines
EP0113070B1 (de) * 1982-12-20 1988-01-13 American Cyanamid Company Verwendung substituierter Nitro- und Cyanoguanidine zur Erhöhung der Ernteerträge
US4639268A (en) * 1985-07-29 1987-01-27 American Cyanamid Company Nitro- and cyanoguanidines as selective preemergence herbicides and plant defoliants
EP0310545A3 (de) * 1987-09-02 1989-07-26 Ciba-Geigy Ag Cyanoguanidine als Härter für Epoxidharze
US5011837A (en) * 1988-08-09 1991-04-30 E. R. Squibb & Sons, Inc. Aryl cyanoguanidines: potassium channel activators and method of making same
GB8908063D0 (en) * 1989-04-11 1989-05-24 Beecham Group Plc Novel compounds

Also Published As

Publication number Publication date
ES2059901T3 (es) 1994-11-16
DE69012451D1 (de) 1994-10-20
KR910000629A (ko) 1991-01-29
EP0405525A3 (en) 1992-03-25
US5087640A (en) 1992-02-11
DK0405525T3 (da) 1994-10-17
JP2749639B2 (ja) 1998-05-13
EP0405525A2 (de) 1991-01-02
JPH0331250A (ja) 1991-02-12
DE69012451T2 (de) 1995-02-02
EP0405525B1 (de) 1994-09-14

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee