ATE109784T1 - Bor-dipeptid-verbindungen, methode zu deren herstellung und pharmazeutische anwendungen. - Google Patents
Bor-dipeptid-verbindungen, methode zu deren herstellung und pharmazeutische anwendungen.Info
- Publication number
- ATE109784T1 ATE109784T1 AT89303450T AT89303450T ATE109784T1 AT E109784 T1 ATE109784 T1 AT E109784T1 AT 89303450 T AT89303450 T AT 89303450T AT 89303450 T AT89303450 T AT 89303450T AT E109784 T1 ATE109784 T1 AT E109784T1
- Authority
- AT
- Austria
- Prior art keywords
- boron
- compounds
- production
- pharmaceutical applications
- dipeptide compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- ZOXJGFHDIHLPTG-UHFFFAOYSA-N Boron Chemical compound [B] ZOXJGFHDIHLPTG-UHFFFAOYSA-N 0.000 title abstract 3
- 229910052796 boron Inorganic materials 0.000 title abstract 3
- 108010016626 Dipeptides Proteins 0.000 title abstract 2
- 230000001315 anti-hyperlipaemic effect Effects 0.000 abstract 2
- 230000000118 anti-neoplastic effect Effects 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/027—Organoboranes and organoborohydrides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/179,555 US4977268A (en) | 1988-04-08 | 1988-04-08 | Boron dipeptide compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE109784T1 true ATE109784T1 (de) | 1994-08-15 |
Family
ID=22657076
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT89303450T ATE109784T1 (de) | 1988-04-08 | 1989-04-07 | Bor-dipeptid-verbindungen, methode zu deren herstellung und pharmazeutische anwendungen. |
Country Status (4)
Country | Link |
---|---|
US (1) | US4977268A (de) |
EP (1) | EP0336772B1 (de) |
AT (1) | ATE109784T1 (de) |
DE (1) | DE68917348D1 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5260427A (en) * | 1991-05-10 | 1993-11-09 | Boron Biolgicals, Inc. | Nucleosidylphosphite-borane compounds and method of making the same |
US5143907A (en) * | 1991-05-10 | 1992-09-01 | Boron Biologicals, Inc. | Phosphite-borane compounds, and method of making and using the same |
CA2176414A1 (en) * | 1995-05-18 | 1996-11-19 | S. David Kimball | Acyl guanidine and amidine prodrugs |
US6017902A (en) * | 1999-02-25 | 2000-01-25 | Brookhaven Science Associates | Boron containing amino acid compounds and methods for their use |
JP2009507915A (ja) * | 2005-09-13 | 2009-02-26 | イッサム リサーチ ディベロップメント カンパニー オブ ザ ヘブリュー ユニバーシティー オブ エルサレム | 抗菌剤としてのアミン−ボラン化合物の使用 |
ATE535531T1 (de) * | 2005-09-13 | 2011-12-15 | Yissum Res Dev Co | Neue aminboranverbindungen und anwendungen davon |
EP1976536A4 (de) | 2005-12-30 | 2011-03-02 | Anacor Pharmaceuticals Inc | Borhaltige kleine moleküle |
US8287839B2 (en) * | 2006-12-04 | 2012-10-16 | Brookhaven Science Associates, Llc | Carboranylporphyrins and uses thereof |
US8444953B2 (en) * | 2007-03-22 | 2013-05-21 | Brookhaven Science Associates, Llc | Symmetric and asymmetric halogen-containing metallocarboranylporphyrins and uses thereof |
US20080279781A1 (en) * | 2007-05-10 | 2008-11-13 | Brookhaven Science Associates, Llc | Glycosylated Carboranylporphyrins and Uses Thereof |
US10763103B2 (en) * | 2015-03-31 | 2020-09-01 | Versum Materials Us, Llc | Boron-containing compounds, compositions, and methods for the deposition of a boron containing films |
WO2017007955A1 (en) | 2015-07-07 | 2017-01-12 | The Research Foundation For The State University Of New York | Use of amine carboxyboranes as therapeutic delivery of carbon monoxide and as general drug delivery system in the presence of reactive oxygen species |
US11447506B2 (en) | 2016-05-09 | 2022-09-20 | Anacor Pharmaceuticals, Inc. | Crystal forms of crisaborole in free form and preparation method and use thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4209510A (en) * | 1978-11-14 | 1980-06-24 | The United States Of America As Represented By The Secretary Of The Army | Ammonia-cyanoborane, sodium iodide complex |
US4312989A (en) * | 1979-08-21 | 1982-01-26 | The United States Of America As Represented By The Secretary Of The Army | Pharmacologically active amine boranes |
EP0034238B1 (de) * | 1979-12-21 | 1985-04-17 | Duke University | Amin-carboxyborane mit pharmakologischer Wirkung |
US4499082A (en) * | 1983-12-05 | 1985-02-12 | E. I. Du Pont De Nemours And Company | α-Aminoboronic acid peptides |
US4587359A (en) * | 1984-05-17 | 1986-05-06 | The United States Of America As Represented By The Secrtary Of The Army | Amine-carbamoylborane adducts |
IT1184317B (it) * | 1985-02-05 | 1987-10-28 | Eniricerche Spa | Retro-inverso analoghi del peptide potenziatore della bradichina bpp5a |
-
1988
- 1988-04-08 US US07/179,555 patent/US4977268A/en not_active Expired - Fee Related
-
1989
- 1989-04-07 DE DE68917348T patent/DE68917348D1/de not_active Expired - Lifetime
- 1989-04-07 EP EP89303450A patent/EP0336772B1/de not_active Expired - Lifetime
- 1989-04-07 AT AT89303450T patent/ATE109784T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0336772A3 (en) | 1990-04-11 |
US4977268A (en) | 1990-12-11 |
EP0336772B1 (de) | 1994-08-10 |
DE68917348D1 (de) | 1994-09-15 |
EP0336772A2 (de) | 1989-10-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |