ATE102924T1 - 1-(4-aminophenyl)-2-piperidinopropanon-derivate verfahren zu deren herstellung und therapeutische verwendung. - Google Patents
1-(4-aminophenyl)-2-piperidinopropanon-derivate verfahren zu deren herstellung und therapeutische verwendung.Info
- Publication number
- ATE102924T1 ATE102924T1 AT90403078T AT90403078T ATE102924T1 AT E102924 T1 ATE102924 T1 AT E102924T1 AT 90403078 T AT90403078 T AT 90403078T AT 90403078 T AT90403078 T AT 90403078T AT E102924 T1 ATE102924 T1 AT E102924T1
- Authority
- AT
- Austria
- Prior art keywords
- piperidinopropanone
- aminophenyl
- preparation
- therapeutic use
- derivatives process
- Prior art date
Links
- 230000001225 therapeutic effect Effects 0.000 title 1
- TUCNEACPLKLKNU-UHFFFAOYSA-N acetyl Chemical compound C[C]=O TUCNEACPLKLKNU-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 229940125692 cardiovascular agent Drugs 0.000 abstract 1
- 239000002327 cardiovascular agent Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- IMCGHZIGRANKHV-AJNGGQMLSA-N tert-butyl (3s,5s)-2-oxo-5-[(2s,4s)-5-oxo-4-propan-2-yloxolan-2-yl]-3-propan-2-ylpyrrolidine-1-carboxylate Chemical compound O1C(=O)[C@H](C(C)C)C[C@H]1[C@H]1N(C(=O)OC(C)(C)C)C(=O)[C@H](C(C)C)C1 IMCGHZIGRANKHV-AJNGGQMLSA-N 0.000 abstract 1
- 230000000304 vasodilatating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8914217A FR2653767B1 (fr) | 1989-10-30 | 1989-10-30 | Derives de 1-(aminophenyl)-2-piperidinopropanone, procede et utilisation en therapeutique. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE102924T1 true ATE102924T1 (de) | 1994-04-15 |
Family
ID=9386921
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90403078T ATE102924T1 (de) | 1989-10-30 | 1990-10-30 | 1-(4-aminophenyl)-2-piperidinopropanon-derivate verfahren zu deren herstellung und therapeutische verwendung. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5128349A (de) |
| EP (1) | EP0426562B1 (de) |
| JP (1) | JPH03209364A (de) |
| AT (1) | ATE102924T1 (de) |
| CA (1) | CA2028764A1 (de) |
| DE (1) | DE69007422T2 (de) |
| DK (1) | DK0426562T3 (de) |
| ES (1) | ES2062457T3 (de) |
| FR (1) | FR2653767B1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2147679B1 (de) | 2001-07-25 | 2014-06-25 | Raptor Pharmaceutical, Inc. | Zusammensetzungen für den Blut-Hirn-Schrankentransport |
| DE10344594A1 (de) * | 2003-09-25 | 2005-05-12 | Basf Ag | Verfahren zur Herstellung von Cyclododecanon |
| EP2392258B1 (de) | 2005-04-28 | 2014-10-08 | Proteus Digital Health, Inc. | Pharma-Informatiksystem |
| CN101594878A (zh) | 2006-09-18 | 2009-12-02 | 雷普特药品公司 | 通过给予受体相关蛋白（rap）-缀合物对肝病症的治疗 |
| PL3395372T3 (pl) | 2009-02-20 | 2022-07-25 | EnhanX Biopharm Inc. | Układ do dostarczania leków na bazie glutationu |
| CN102458374A (zh) | 2009-05-06 | 2012-05-16 | 实验室护肤股份有限公司 | 包含活性剂-磷酸钙颗粒复合物的皮肤递送组合物及其使用方法 |
| US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1618005A1 (de) * | 1966-09-22 | 1971-09-09 | Thomae Gmbh Dr K | Verfahren zur Herstellung von neuen Amino-dihalogen-phenyl-aethylaminen |
| DE1618007A1 (de) * | 1967-05-09 | 1970-10-29 | Thomae Gmbh Dr K | Verfahren zur Herstellung von neuen Amino-monohalogenphenylaethanolaminen |
| GB1262965A (en) * | 1969-03-21 | 1972-02-09 | Ferrosan As | Butyrophenones |
| US4282206A (en) * | 1979-11-15 | 1981-08-04 | Westwood Pharmaceuticals Inc. | Method of protecting human skin from ultraviolet radiation |
| MA20246A1 (fr) * | 1983-10-14 | 1985-07-01 | Lafon Labor | Procede de preparation de nouveaux derives de 1-(acetylaminophenyl)-2 aminopropanone. |
| FR2569184A1 (fr) * | 1984-08-20 | 1986-02-21 | Lafon Labor | Derives de 1-(aminophenyl) therapeutique et leur procede de preparation |
-
1989
- 1989-10-30 FR FR8914217A patent/FR2653767B1/fr not_active Expired - Lifetime
-
1990
- 1990-10-29 CA CA002028764A patent/CA2028764A1/en not_active Abandoned
- 1990-10-29 US US07/604,802 patent/US5128349A/en not_active Expired - Fee Related
- 1990-10-30 JP JP2290950A patent/JPH03209364A/ja active Pending
- 1990-10-30 EP EP90403078A patent/EP0426562B1/de not_active Expired - Lifetime
- 1990-10-30 DE DE69007422T patent/DE69007422T2/de not_active Expired - Fee Related
- 1990-10-30 ES ES90403078T patent/ES2062457T3/es not_active Expired - Lifetime
- 1990-10-30 AT AT90403078T patent/ATE102924T1/de not_active IP Right Cessation
- 1990-10-30 DK DK90403078.0T patent/DK0426562T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| CA2028764A1 (en) | 1991-05-01 |
| EP0426562B1 (de) | 1994-03-16 |
| FR2653767A1 (fr) | 1991-05-03 |
| DE69007422T2 (de) | 1994-07-14 |
| EP0426562A1 (de) | 1991-05-08 |
| FR2653767B1 (fr) | 1992-02-14 |
| JPH03209364A (ja) | 1991-09-12 |
| US5128349A (en) | 1992-07-07 |
| ES2062457T3 (es) | 1994-12-16 |
| DK0426562T3 (da) | 1994-07-25 |
| DE69007422D1 (de) | 1994-04-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |