ATA99478A - Verfahren zur herstellung von (14-14c)- daunorubicin und(14-14c)-doxorubicin - Google Patents

Verfahren zur herstellung von (14-14c)- daunorubicin und(14-14c)-doxorubicin

Info

Publication number
ATA99478A
ATA99478A AT99478A AT99478A ATA99478A AT A99478 A ATA99478 A AT A99478A AT 99478 A AT99478 A AT 99478A AT 99478 A AT99478 A AT 99478A AT A99478 A ATA99478 A AT A99478A
Authority
AT
Austria
Prior art keywords
daunorubicin
doxorubicin
preparation
Prior art date
Application number
AT99478A
Other languages
English (en)
Other versions
AT353968B (de
Inventor
Gian Piero Vicario
Sergio Penco
Federico Arcamone
Original Assignee
Farmaceutici Italia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmaceutici Italia filed Critical Farmaceutici Italia
Publication of ATA99478A publication Critical patent/ATA99478A/de
Application granted granted Critical
Publication of AT353968B publication Critical patent/AT353968B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT99478A 1977-02-16 1978-02-13 Verfahren zur herstellung von (14-14c)- daunorubicin und(14-14c)-doxorubicin AT353968B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB6372/77A GB1566330A (en) 1977-02-16 1977-02-16 Anthracycline glycosides

Publications (2)

Publication Number Publication Date
ATA99478A true ATA99478A (de) 1979-05-15
AT353968B AT353968B (de) 1979-12-10

Family

ID=9813304

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99478A AT353968B (de) 1977-02-16 1978-02-13 Verfahren zur herstellung von (14-14c)- daunorubicin und(14-14c)-doxorubicin

Country Status (9)

Country Link
US (1) US4211864A (de)
JP (2) JPS53127457A (de)
AT (1) AT353968B (de)
BE (1) BE863957A (de)
CH (1) CH639356A5 (de)
DE (1) DE2806454C2 (de)
FR (1) FR2381060A1 (de)
GB (1) GB1566330A (de)
NL (1) NL7801564A (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0174962A1 (de) * 1984-03-19 1986-03-26 The Commonwealth Of Australia Markierung organischer moleküle
AU568738B2 (en) * 1984-03-19 1988-01-07 Commonwealth Of Australia, The Labelling of organic molecules
US5187266A (en) * 1986-06-30 1993-02-16 Board Of Regents The University Of Texas System Antitumor aldophosphamide glycoside and dideoxyuridine derivatives
JPS63310830A (ja) * 1987-06-10 1988-12-19 Meiji Seika Kaisha Ltd 抗レトロウイルス剤
US4997922A (en) * 1988-09-06 1991-03-05 Sanraku Incorporated Anthracycline derivatives
IT1230505B (it) * 1988-10-11 1991-10-25 Sicor Spa Procedimento per la conversione della daunorubicina in doxorubicina.
EP1263803B1 (de) * 2000-03-13 2007-09-19 BioCure, Inc. Embolische zusammensetzungen
US7388083B2 (en) * 2005-03-07 2008-06-17 Solux Corporation Epimerization of 4′-C bond and modification of 14-CH3-(CO)-fragment in anthracyclin antibiotics
US9035032B2 (en) * 2005-12-13 2015-05-19 Solux Corporation Method for preparing 4-demethyldaunorubicin
US8802830B2 (en) * 2005-12-20 2014-08-12 Solux Corporation Synthesis of epirubicin from 13-dihydrodaunorubicine
US8357785B2 (en) * 2008-01-08 2013-01-22 Solux Corporation Method of aralkylation of 4′-hydroxyl group of anthracylins
WO2023220641A2 (en) 2022-05-11 2023-11-16 Juno Therapeutics, Inc. Methods and uses related to t cell therapy and production of same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3803124A (en) * 1968-04-12 1974-04-09 Farmaceutici It Soc Process for the preparation of adriamycin and adriamycinone and adriamycin derivatives
US3945993A (en) * 1971-06-07 1976-03-23 Rutgers Research And Educational Foundation Derivatives of polyene macrolide antibiotics

Also Published As

Publication number Publication date
DE2806454C2 (de) 1986-06-12
NL7801564A (nl) 1978-08-18
DE2806454A1 (de) 1978-08-17
CH639356A5 (de) 1983-11-15
FR2381060B1 (de) 1982-05-21
JPS6330919B2 (de) 1988-06-21
JPS63225394A (ja) 1988-09-20
AT353968B (de) 1979-12-10
BE863957A (fr) 1978-08-16
GB1566330A (en) 1980-04-30
JPS53127457A (en) 1978-11-07
FR2381060A1 (fr) 1978-09-15
JPH0140037B2 (de) 1989-08-24
US4211864A (en) 1980-07-08

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee