ATA901478A - METHOD FOR PRODUCING NEW HETEROCYCLIC ANTICHOLINERGIC SUBSTANCES - Google Patents

METHOD FOR PRODUCING NEW HETEROCYCLIC ANTICHOLINERGIC SUBSTANCES

Info

Publication number
ATA901478A
ATA901478A AT0901478A AT901478A ATA901478A AT A901478 A ATA901478 A AT A901478A AT 0901478 A AT0901478 A AT 0901478A AT 901478 A AT901478 A AT 901478A AT A901478 A ATA901478 A AT A901478A
Authority
AT
Austria
Prior art keywords
producing new
new heterocyclic
anticholinergic substances
anticholinergic
substances
Prior art date
Application number
AT0901478A
Other languages
German (de)
Other versions
AT366380B (en
Inventor
Nicholas Stephan Bodor
Original Assignee
Recordati Chem Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Recordati Chem Pharm filed Critical Recordati Chem Pharm
Publication of ATA901478A publication Critical patent/ATA901478A/en
Application granted granted Critical
Publication of AT366380B publication Critical patent/AT366380B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79Acids; Esters
    • C07D213/80Acids; Esters in position 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00Thiocarboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/90Benzo [c] furans; Hydrogenated benzo [c] furans with an oxygen atom in position 1 and a nitrogen atom in position 3, or vice versa
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D453/00Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT0901478A 1977-12-16 1978-12-18 METHOD FOR PRODUCING NEW HETEROCYCLIC ANTICHOLINERGIC SUBSTANCES AT366380B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US86121077A 1977-12-16 1977-12-16

Publications (2)

Publication Number Publication Date
ATA901478A true ATA901478A (en) 1981-08-15
AT366380B AT366380B (en) 1982-04-13

Family

ID=25335183

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0901478A AT366380B (en) 1977-12-16 1978-12-18 METHOD FOR PRODUCING NEW HETEROCYCLIC ANTICHOLINERGIC SUBSTANCES

Country Status (15)

Country Link
JP (1) JPS5498711A (en)
AR (1) AR222478A1 (en)
AT (1) AT366380B (en)
AU (1) AU531835B2 (en)
CA (1) CA1102345A (en)
DE (1) DE2854308A1 (en)
DK (1) DK534178A (en)
ES (1) ES476048A1 (en)
FR (1) FR2422624A1 (en)
GB (1) GB2010270B (en)
IE (1) IE48012B1 (en)
IT (1) IT1101735B (en)
NL (1) NL7812257A (en)
NO (1) NO148776C (en)
SE (1) SE436027B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3045055A1 (en) * 1980-11-29 1982-07-01 Celamerck Gmbh & Co Kg, 6507 Ingelheim HETEROCYCLIC COMPOUNDS
JPS5993075A (en) * 1982-11-18 1984-05-29 Shionogi & Co Ltd Preparation of 1-phthalidyl-5-fluorouracil derivative
US5008111A (en) * 1984-10-11 1991-04-16 Schering Corporation Physiological means of enhancing transdermal delivery of drugs
US4824676A (en) * 1984-10-11 1989-04-25 Schering Corporation Physiological means of enhancing transdermal delivery of drugs
FR2703046B1 (en) * 1993-03-26 1995-05-05 Poudres & Explosifs Ste Nale Process for the preparation of alpha-monohalogenated oxalates and haloglyoxalates and new alpha-monohalogenated oxalates and haloglyoxalates.
AUPN814496A0 (en) 1996-02-19 1996-03-14 Monash University Dermal penetration enhancer
US5962505A (en) * 1998-08-31 1999-10-05 Bobrove; Arthur M. Method for treating hot flashes in humans
US6433003B1 (en) 1999-04-23 2002-08-13 Arthur M. Bobrove Method for treating hyperhidrosis in mammals
AR044134A1 (en) 2003-05-02 2005-08-24 Novartis Ag DERIVATIVES OF QUINUCLIDINE, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS.
JP5401092B2 (en) 2005-06-03 2014-01-29 アクルックス・ディ・ディ・エス・プロプライエタリー・リミテッド Methods and compositions for transdermal drug delivery
KR20080089461A (en) * 2005-12-30 2008-10-06 랜박시 래보러터리스 리미티드 Muscarinic receptor antagonists
EA019760B1 (en) 2007-11-02 2014-06-30 АКРУКС ДиДиЭс ПиТиУай ЭлТиДи Transdermal delivery system, method for transdermal administration and method of preparing transdermal delivery system
CN110526864A (en) * 2012-10-05 2019-12-03 斯菲拉制药私人有限公司 New compound, its synthesis and application thereof
DE102013013397A1 (en) 2013-08-13 2015-03-12 Epinamics Gmbh Aerosol dispenser for transdermal pharmaceutical compositions
CN110041264A (en) * 2019-04-11 2019-07-23 贺州学院 A kind of adamantyl glyoxaline ion liquid and preparation method thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL101555C (en) * 1955-03-19
BE798253A (en) * 1973-04-16 1973-10-16 Bekaert Sa Nv SEATING
US3998815A (en) * 1974-06-24 1976-12-21 Interx Research Corporation 1-hydrocarbonoyloxymethyl-3-carbamoyl or 3-carboethoxy-pyridinium salts

Also Published As

Publication number Publication date
NO148776B (en) 1983-09-05
SE436027B (en) 1984-11-05
IE48012B1 (en) 1984-09-05
AU531835B2 (en) 1983-09-08
NO148776C (en) 1983-12-14
FR2422624B1 (en) 1983-10-14
JPS5498711A (en) 1979-08-03
CA1102345A (en) 1981-06-02
NO784229L (en) 1979-06-19
NL7812257A (en) 1979-06-19
AU4264678A (en) 1979-06-21
IE782499L (en) 1979-06-16
DK534178A (en) 1979-06-17
IT7830735A0 (en) 1978-12-12
DE2854308A1 (en) 1979-06-21
GB2010270B (en) 1982-10-20
IT1101735B (en) 1985-10-07
SE7812911L (en) 1979-06-17
FR2422624A1 (en) 1979-11-09
GB2010270A (en) 1979-06-27
AT366380B (en) 1982-04-13
AR222478A1 (en) 1981-05-29
ES476048A1 (en) 1979-11-01

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