ATA682376A - METHOD FOR PRODUCING NEW 2-AMINO-1-PHENYLAETHANOLEN- (1) AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS - Google Patents

METHOD FOR PRODUCING NEW 2-AMINO-1-PHENYLAETHANOLEN- (1) AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS

Info

Publication number
ATA682376A
ATA682376A AT682376A AT682376A ATA682376A AT A682376 A ATA682376 A AT A682376A AT 682376 A AT682376 A AT 682376A AT 682376 A AT682376 A AT 682376A AT A682376 A ATA682376 A AT A682376A
Authority
AT
Austria
Prior art keywords
phenylaethanolen
amino
pharmaceutically acceptable
acceptable salts
producing new
Prior art date
Application number
AT682376A
Other languages
German (de)
Other versions
AT347427B (en
Inventor
Leif Ake Svensson
Lars Magnus Soerenby
Kjell Ingvar Leopold Wetterlin
Original Assignee
Draco Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Draco Ab filed Critical Draco Ab
Publication of ATA682376A publication Critical patent/ATA682376A/en
Application granted granted Critical
Publication of AT347427B publication Critical patent/AT347427B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/04Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reaction of ammonia or amines with olefin oxides or halohydrins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/281,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/301,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • C07D265/321,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings with oxygen atoms directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
AT682376A 1975-10-01 1976-09-15 METHOD FOR PRODUCING NEW 2-AMINO-1-PHENYLAETHANOLEN- (1) AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS AT347427B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7510988A SE7510988L (en) 1975-10-01 1975-10-01 NEW PHARMACEUTICAL ACTIVE ASSOCIATIONS

Publications (2)

Publication Number Publication Date
ATA682376A true ATA682376A (en) 1978-05-15
AT347427B AT347427B (en) 1978-12-27

Family

ID=20325688

Family Applications (1)

Application Number Title Priority Date Filing Date
AT682376A AT347427B (en) 1975-10-01 1976-09-15 METHOD FOR PRODUCING NEW 2-AMINO-1-PHENYLAETHANOLEN- (1) AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS

Country Status (19)

Country Link
JP (1) JPS5242840A (en)
AT (1) AT347427B (en)
AU (1) AU503212B2 (en)
BE (1) BE846837A (en)
CS (2) CS199644B2 (en)
DD (1) DD126278A5 (en)
DE (1) DE2640972A1 (en)
DK (1) DK141622B (en)
ES (1) ES451979A1 (en)
FI (1) FI762660A (en)
FR (1) FR2326183A1 (en)
GB (1) GB1542317A (en)
LU (1) LU75916A1 (en)
NL (1) NL7610845A (en)
NO (1) NO763345L (en)
NZ (1) NZ182165A (en)
SE (1) SE7510988L (en)
SU (2) SU638252A3 (en)
ZA (1) ZA765331B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3163871D1 (en) 1980-07-09 1984-07-05 Draco Ab 1-(dihydroxyphenyl)-2-amino-ethanol derivatives; preparation, compositions and intermediates
EP0103830A3 (en) * 1982-09-22 1985-07-31 Bayer Ag Phenylethylemine derivatires as growth stimulators
SI2332921T1 (en) * 2003-06-17 2016-06-30 Arena Pharmaceuticals, Inc. 8-Chloro-1 -methyl-2,3,4,5-tetrahydro-1 H-3benzazapine Hydrochloride
CA2646044A1 (en) 2006-04-03 2007-10-25 Arena Pharmaceuticals, Inc. Processes for the preparation of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine and intermediates related thereto
SG177128A1 (en) 2006-12-05 2012-01-30 Arena Pharm Inc Processes for preparing (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine and intermediates thereof
JP5491421B2 (en) 2008-03-04 2014-05-14 アリーナ ファーマシューティカルズ, インコーポレイテッド Process for the preparation of intermediates related to the 5-HT2C agonist (R) -8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
EP2443080A2 (en) 2009-06-18 2012-04-25 Arena Pharmaceuticals, Inc. Process for the preparation of 5-ht2c receptor agonists
KR20130112848A (en) 2010-06-02 2013-10-14 아레나 파마슈티칼스, 인크. Processes for the preparation of 5-ht2c receptor agonists
SG188365A1 (en) 2010-09-01 2013-04-30 Arena Pharm Inc Administration of lorcaserin to individuals with renal impairment
MX2013002422A (en) 2010-09-01 2013-05-17 Arena Pharm Inc Salts of lorcaserin with optically active acids.
EP3485878A1 (en) 2010-09-01 2019-05-22 Arena Pharmaceuticals, Inc. Modified-release dosage forms of 5-ht2c agonists useful for weight management
CN103189360A (en) 2010-09-01 2013-07-03 艾尼纳制药公司 Non-hygroscopic salts of 5-HT2C agonists
AU2012392187B2 (en) 2012-10-09 2018-07-12 Arena Pharmaceuticals, Inc. Method of weight management

Also Published As

Publication number Publication date
CS199644B2 (en) 1980-07-31
DD126278A5 (en) 1977-07-06
DE2640972A1 (en) 1977-04-14
SU674669A3 (en) 1979-07-15
ES451979A1 (en) 1978-01-01
SE7510988L (en) 1977-04-02
AU503212B2 (en) 1979-08-30
FR2326183A1 (en) 1977-04-29
DK141622B (en) 1980-05-12
SU638252A3 (en) 1978-12-15
NL7610845A (en) 1977-04-05
CS199643B2 (en) 1980-07-31
JPS5242840A (en) 1977-04-04
FI762660A (en) 1977-04-02
AT347427B (en) 1978-12-27
BE846837A (en) 1977-04-01
DK439776A (en) 1977-04-02
LU75916A1 (en) 1978-05-16
NZ182165A (en) 1978-07-10
NO763345L (en) 1977-04-04
ZA765331B (en) 1977-08-31
GB1542317A (en) 1979-03-14
AU1812276A (en) 1978-04-06

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