AT383599B - Process for the preparation of novel racemic and optically active E-homo-eburnane derivatives and of acid addition salts thereof - Google Patents
Process for the preparation of novel racemic and optically active E-homo-eburnane derivatives and of acid addition salts thereofInfo
- Publication number
- AT383599B AT383599B AT238983A AT238983A AT383599B AT 383599 B AT383599 B AT 383599B AT 238983 A AT238983 A AT 238983A AT 238983 A AT238983 A AT 238983A AT 383599 B AT383599 B AT 383599B
- Authority
- AT
- Austria
- Prior art keywords
- acid addition
- optically active
- addition salts
- homo
- preparation
- Prior art date
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- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention relates to a process for the preparation of novel racemic and optically active E-homo-eburnane derivatives and the physiologically tolerated acid addition salts thereof. The novel compounds correspond to the general formula I in which R<1> and R<2> are identical or different and are alkyl groups having 1 to 6 carbon atoms. The compounds are obtained by cyclization of racemic or optically active compounds of the general formula II or acid addition salts thereof, in which A is hydrogen or the groups of the general formulae -CH2-CH(CO2R<1>)2 or -CH2-C(CO2R<1>)2- -CH2-CH(CO2R<1>)2 and R<3> is identical to R<1> or, if A is hydrogen, R<3> can likewise be hydrogen. The compounds of the general formula (I) show antidepressant and antihypoxic properties. <IMAGE>
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT238983A AT383599B (en) | 1982-06-30 | 1983-06-29 | Process for the preparation of novel racemic and optically active E-homo-eburnane derivatives and of acid addition salts thereof |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU822130A HU190399B (en) | 1982-06-30 | 1982-06-30 | Process for the production of e-homo-eburnane-derivatives |
AT238983A AT383599B (en) | 1982-06-30 | 1983-06-29 | Process for the preparation of novel racemic and optically active E-homo-eburnane derivatives and of acid addition salts thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
ATA238983A ATA238983A (en) | 1986-12-15 |
AT383599B true AT383599B (en) | 1987-07-27 |
Family
ID=25598344
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT238983A AT383599B (en) | 1982-06-30 | 1983-06-29 | Process for the preparation of novel racemic and optically active E-homo-eburnane derivatives and of acid addition salts thereof |
Country Status (1)
Country | Link |
---|---|
AT (1) | AT383599B (en) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3026584A1 (en) * | 1979-08-13 | 1981-05-07 | Richter Gedeon Vegyészeti Gyár R.T., Budapest | 10-HALOGEN-14-OXON-15-HYDROXY-E-HOMOEBURN OTHER DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THE MEDICINAL PRODUCTS CONTAINING THEM |
-
1983
- 1983-06-29 AT AT238983A patent/AT383599B/en not_active IP Right Cessation
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3026584A1 (en) * | 1979-08-13 | 1981-05-07 | Richter Gedeon Vegyészeti Gyár R.T., Budapest | 10-HALOGEN-14-OXON-15-HYDROXY-E-HOMOEBURN OTHER DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THE MEDICINAL PRODUCTS CONTAINING THEM |
Also Published As
Publication number | Publication date |
---|---|
ATA238983A (en) | 1986-12-15 |
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Legal Events
Date | Code | Title | Description |
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ELJ | Ceased due to non-payment of the annual fee |