AT378767B - Verfahren zur herstellung von kristallinem, stabilem prostaglandin f 2alpha - Google Patents
Verfahren zur herstellung von kristallinem, stabilem prostaglandin f 2alphaInfo
- Publication number
- AT378767B AT378767B AT337681A AT337681A AT378767B AT 378767 B AT378767 B AT 378767B AT 337681 A AT337681 A AT 337681A AT 337681 A AT337681 A AT 337681A AT 378767 B AT378767 B AT 378767B
- Authority
- AT
- Austria
- Prior art keywords
- 2alpha
- producing crystalline
- stable prostaglandin
- prostaglandin
- stable
- Prior art date
Links
- PXGPLTODNUVGFL-BRIYLRKRSA-N (E,Z)-(1R,2R,3R,5S)-7-(3,5-Dihydroxy-2-((3S)-(3-hydroxy-1-octenyl))cyclopentyl)-5-heptenoic acid Chemical compound CCCCC[C@H](O)C=C[C@H]1[C@H](O)C[C@H](O)[C@@H]1CC=CCCCC(O)=O PXGPLTODNUVGFL-BRIYLRKRSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- PXGPLTODNUVGFL-UHFFFAOYSA-N prostaglandin F2alpha Natural products CCCCCC(O)C=CC1C(O)CC(O)C1CC=CCCCC(O)=O PXGPLTODNUVGFL-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU192080A HU180161B (en) | 1980-08-01 | 1980-08-01 | Process for preparing crystalline,stable prostaglandin f down 2alpha with a melting point over 35 c from contaminated prostaglandin f down 2alpha containing 50-98% prostaglandin f down 2alpha |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA337681A ATA337681A (de) | 1985-02-15 |
| AT378767B true AT378767B (de) | 1985-09-25 |
Family
ID=10956846
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT337681A AT378767B (de) | 1980-08-01 | 1981-07-31 | Verfahren zur herstellung von kristallinem, stabilem prostaglandin f 2alpha |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS5764664A (ru) |
| AT (1) | AT378767B (ru) |
| CH (1) | CH648826A5 (ru) |
| DE (1) | DE3129637A1 (ru) |
| DK (1) | DK156829C (ru) |
| ES (1) | ES8204419A1 (ru) |
| FR (1) | FR2487828A1 (ru) |
| GR (1) | GR74277B (ru) |
| HU (1) | HU180161B (ru) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS49100059A (ru) * | 1973-02-03 | 1974-09-20 | ||
| US3941886A (en) * | 1973-09-21 | 1976-03-02 | Alza Corporation | Pharmaceutical compositions containing crystalline racemic 9α, 11α, 15(S)-trihydroxy-5-cis, 13-trans-prostadienoic acid |
-
1980
- 1980-08-01 HU HU192080A patent/HU180161B/hu unknown
-
1981
- 1981-07-28 DE DE19813129637 patent/DE3129637A1/de active Granted
- 1981-07-30 FR FR8114832A patent/FR2487828A1/fr active Granted
- 1981-07-31 AT AT337681A patent/AT378767B/de not_active IP Right Cessation
- 1981-07-31 GR GR65683A patent/GR74277B/el unknown
- 1981-07-31 ES ES504993A patent/ES8204419A1/es not_active Expired
- 1981-07-31 CH CH497381A patent/CH648826A5/de not_active IP Right Cessation
- 1981-07-31 DK DK344081A patent/DK156829C/da not_active IP Right Cessation
- 1981-07-31 JP JP11943681A patent/JPS5764664A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DK156829C (da) | 1990-02-19 |
| HU180161B (en) | 1983-02-28 |
| GR74277B (ru) | 1984-06-21 |
| ES504993A0 (es) | 1982-05-16 |
| JPS5764664A (en) | 1982-04-19 |
| ATA337681A (de) | 1985-02-15 |
| DE3129637C2 (ru) | 1991-05-29 |
| ES8204419A1 (es) | 1982-05-16 |
| DK344081A (da) | 1982-02-02 |
| CH648826A5 (de) | 1985-04-15 |
| FR2487828B1 (ru) | 1984-01-06 |
| DK156829B (da) | 1989-10-09 |
| DE3129637A1 (de) | 1982-05-13 |
| FR2487828A1 (fr) | 1982-02-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ELJ | Ceased due to non-payment of the annual fee |