AT355721B - Verfahren zur herstellung von neuen amino-spiro (oxa(oder thia)-cycloalkan-penam)- carbonsaeuren sowie von deren salzen und estern - Google Patents

Verfahren zur herstellung von neuen amino-spiro (oxa(oder thia)-cycloalkan-penam)- carbonsaeuren sowie von deren salzen und estern

Info

Publication number
AT355721B
AT355721B AT32078A AT32078A AT355721B AT 355721 B AT355721 B AT 355721B AT 32078 A AT32078 A AT 32078A AT 32078 A AT32078 A AT 32078A AT 355721 B AT355721 B AT 355721B
Authority
AT
Austria
Prior art keywords
cycloalkan
penam
thia
oxa
esters
Prior art date
Application number
AT32078A
Other languages
German (de)
English (en)
Other versions
ATA32078A (de
Original Assignee
Ucb Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb Sa filed Critical Ucb Sa
Publication of ATA32078A publication Critical patent/ATA32078A/de
Application granted granted Critical
Publication of AT355721B publication Critical patent/AT355721B/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D305/00Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/02Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D305/04Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D305/08Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/20Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hydrogen atoms and substituted hydrocarbon radicals directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D331/00Heterocyclic compounds containing rings of less than five members, having one sulfur atom as the only ring hetero atom
    • C07D331/04Four-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30Hetero atoms other than halogen
    • C07D333/34Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D335/00Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/02Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/10Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT32078A 1977-01-18 1978-01-17 Verfahren zur herstellung von neuen amino-spiro (oxa(oder thia)-cycloalkan-penam)- carbonsaeuren sowie von deren salzen und estern AT355721B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1905/77A GB1567561A (en) 1977-01-18 1977-01-18 Amino-spiro(oxa-(orthia)cycloalkane-penam) - carboxylic acids

Publications (2)

Publication Number Publication Date
ATA32078A ATA32078A (de) 1979-08-15
AT355721B true AT355721B (de) 1980-03-25

Family

ID=9730099

Family Applications (1)

Application Number Title Priority Date Filing Date
AT32078A AT355721B (de) 1977-01-18 1978-01-17 Verfahren zur herstellung von neuen amino-spiro (oxa(oder thia)-cycloalkan-penam)- carbonsaeuren sowie von deren salzen und estern

Country Status (26)

Country Link
US (1) US4137236A (US20100223739A1-20100909-C00005.png)
JP (1) JPS5390290A (US20100223739A1-20100909-C00005.png)
AT (1) AT355721B (US20100223739A1-20100909-C00005.png)
AU (1) AU512338B2 (US20100223739A1-20100909-C00005.png)
BE (1) BE862972A (US20100223739A1-20100909-C00005.png)
CA (1) CA1101411A (US20100223739A1-20100909-C00005.png)
CH (1) CH634324A5 (US20100223739A1-20100909-C00005.png)
DD (1) DD135284A5 (US20100223739A1-20100909-C00005.png)
DE (1) DE2801849A1 (US20100223739A1-20100909-C00005.png)
DK (1) DK15678A (US20100223739A1-20100909-C00005.png)
ES (1) ES466053A1 (US20100223739A1-20100909-C00005.png)
FI (1) FI780088A (US20100223739A1-20100909-C00005.png)
FR (1) FR2377408A1 (US20100223739A1-20100909-C00005.png)
GB (1) GB1567561A (US20100223739A1-20100909-C00005.png)
HU (1) HU173788B (US20100223739A1-20100909-C00005.png)
IL (1) IL53825A (US20100223739A1-20100909-C00005.png)
IT (1) IT1103123B (US20100223739A1-20100909-C00005.png)
LU (1) LU78885A1 (US20100223739A1-20100909-C00005.png)
NL (1) NL7800397A (US20100223739A1-20100909-C00005.png)
NO (1) NO780110L (US20100223739A1-20100909-C00005.png)
PL (1) PL204066A1 (US20100223739A1-20100909-C00005.png)
PT (1) PT67537B (US20100223739A1-20100909-C00005.png)
SE (1) SE7800367L (US20100223739A1-20100909-C00005.png)
SU (1) SU786902A3 (US20100223739A1-20100909-C00005.png)
YU (1) YU8578A (US20100223739A1-20100909-C00005.png)
ZA (1) ZA78304B (US20100223739A1-20100909-C00005.png)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2052496B (en) * 1979-06-25 1983-06-29 Ucb Sa 6 - amino - spiro - (penam - 2,4' - piperidine) - 3 - carboxylic acid derivatives
GB2052497B (en) * 1979-06-25 1983-06-29 Ucb Sa 6 - amino - spiro - (penam - 2,4' - piperidine) - 3 - carboxylic acid derivatives
ES2147162B1 (es) 1999-01-27 2001-03-16 Lacer Sa "s-nitrosotioles como agentes para el tratamiento de disfunciones circulatorias".
EP1939179A1 (en) 2006-12-28 2008-07-02 Lacer, S.A. Stable S-nitrosothiols, method of synthesis and use
EP2601940A1 (en) 2011-12-05 2013-06-12 Lacer, S.A. (4-mercapto-piperidin-4-yl)-aminoacetic acid derivatives, pharmaceutical compositions and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3047467A (en) * 1957-08-02 1962-07-31 Beecham Res Lab Process for the preparation of penicillins
US3129217A (en) * 1959-08-19 1964-04-14 Beecham Group Ltd Derivatives of 6-(9-anthramido) penicillanic acid
US3134767A (en) * 1960-04-20 1964-05-26 Beecham Group Ltd Synthetic penicillin
US3210337A (en) * 1962-09-21 1965-10-05 Smith Kline French Lab 6-(benzofurylcarboxamido)- and 6-(thianaphthenylcarboxamido)-penicillanic acid derivatives

Also Published As

Publication number Publication date
IL53825A (en) 1981-01-30
GB1567561A (en) 1980-05-14
YU8578A (en) 1983-04-30
DE2801849A1 (de) 1978-07-20
PT67537A (fr) 1978-02-01
JPS5390290A (en) 1978-08-08
LU78885A1 (fr) 1978-09-18
SU786902A3 (ru) 1980-12-07
NO780110L (no) 1978-07-19
PL204066A1 (pl) 1979-04-09
PT67537B (fr) 1979-06-15
CA1101411A (en) 1981-05-19
IT1103123B (it) 1985-10-14
ES466053A1 (es) 1978-10-01
US4137236A (en) 1979-01-30
HU173788B (hu) 1979-08-28
AU3249578A (en) 1979-07-26
AU512338B2 (en) 1980-10-02
ATA32078A (de) 1979-08-15
DK15678A (da) 1978-07-19
IL53825A0 (en) 1978-04-30
FR2377408B1 (US20100223739A1-20100909-C00005.png) 1980-04-18
BE862972A (fr) 1978-07-17
DD135284A5 (de) 1979-04-25
FR2377408A1 (fr) 1978-08-11
ZA78304B (en) 1978-12-27
SE7800367L (sv) 1978-07-19
NL7800397A (nl) 1978-07-20
FI780088A (fi) 1978-07-19
CH634324A5 (fr) 1983-01-31
IT7847658A0 (it) 1978-01-17

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee