AT355238B - Verfahren zur herstellung eines neuen hentriakontapeptids - Google Patents

Verfahren zur herstellung eines neuen hentriakontapeptids

Info

Publication number
AT355238B
AT355238B AT178877A AT178877A AT355238B AT 355238 B AT355238 B AT 355238B AT 178877 A AT178877 A AT 178877A AT 178877 A AT178877 A AT 178877A AT 355238 B AT355238 B AT 355238B
Authority
AT
Austria
Prior art keywords
contapeptide
hentria
producing
new
new hentria
Prior art date
Application number
AT178877A
Other languages
German (de)
English (en)
Other versions
ATA178877A (de
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ATA178877A publication Critical patent/ATA178877A/de
Application granted granted Critical
Publication of AT355238B publication Critical patent/AT355238B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/675—Beta-endorphins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/28—Bound to a nonpeptide drug, nonpeptide label, nonpeptide carrier, or a nonpeptide resin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AT178877A 1976-03-17 1977-03-16 Verfahren zur herstellung eines neuen hentriakontapeptids AT355238B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/667,747 US4038222A (en) 1976-03-17 1976-03-17 Untriakontapeptide with opiate activity

Publications (2)

Publication Number Publication Date
ATA178877A ATA178877A (de) 1979-07-15
AT355238B true AT355238B (de) 1980-02-25

Family

ID=24679466

Family Applications (1)

Application Number Title Priority Date Filing Date
AT178877A AT355238B (de) 1976-03-17 1977-03-16 Verfahren zur herstellung eines neuen hentriakontapeptids

Country Status (26)

Country Link
US (2) US4038222A (pt-PT)
JP (1) JPS52113958A (pt-PT)
AR (2) AR222778A1 (pt-PT)
AT (1) AT355238B (pt-PT)
AU (1) AU514499B2 (pt-PT)
BE (1) BE852510A (pt-PT)
CA (1) CA1092602A (pt-PT)
CH (1) CH625785A5 (pt-PT)
DE (1) DE2711487C2 (pt-PT)
DK (1) DK149203C (pt-PT)
ES (2) ES456901A1 (pt-PT)
FI (1) FI63391C (pt-PT)
FR (1) FR2348912A1 (pt-PT)
GB (1) GB1563654A (pt-PT)
GR (1) GR63092B (pt-PT)
IE (1) IE44226B1 (pt-PT)
IL (1) IL51660A (pt-PT)
LU (1) LU76963A1 (pt-PT)
MC (1) MC1137A1 (pt-PT)
NL (1) NL7702849A (pt-PT)
NO (1) NO147105C (pt-PT)
NZ (1) NZ183605A (pt-PT)
PH (1) PH13864A (pt-PT)
PT (1) PT66311B (pt-PT)
SE (1) SE436354B (pt-PT)
ZA (1) ZA771593B (pt-PT)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4320117A (en) * 1976-06-21 1982-03-16 Imperial Chemical Industries Limited Polypeptide
US4123523A (en) * 1976-06-21 1978-10-31 Imperial Chemical Industries Limited Analgesic and sedative polypeptides
US4371463A (en) * 1977-02-17 1983-02-01 The United States Of America As Represented By The Department Of Health And Human Services Enzyme-resistant opiate pentapeptides
US4081434A (en) * 1977-03-11 1978-03-28 Hoffmann-La Roche Inc. Novel analogs of β-endorphin
US4098781A (en) * 1977-03-11 1978-07-04 American Home Products Corporation Polypeptides with morphine-like activity
US4317770A (en) * 1977-03-11 1982-03-02 Hoffmann-La Roche Inc. D-amino acid analogs of beta-endorphin
US4127521A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel octacosapeptides, intermediates therefor and pharmaceutical compositions and methods employing said octacosapeptides
US4127523A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel undecapeptides, intermediates therefor, and compositions and methods employing said undecapeptides
US4127532A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel heptapeptides, intermediates therefor, and compositions and methods employing said heptapeptides
US4127519A (en) * 1977-06-16 1978-11-28 Coy David Howard Octadecapeptides, intermediates therefor, and compositions and methods employing said octadecapeptides
US4127524A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel dodecapeptides, intermediates therefor, and compositions and methods employing said dodecapeptides
US4127538A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel pentacosapeptides, intermediates therefor and pharmaceutical compositions and methods employing said pentacosapeptides
US4127525A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel tridecapeptides, intermediates therefor, and compositions and methods employing said tridecapeptides
US4127517A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel docosapeptides, intermediates therefore and pharmaceutical compositions and methods employing said docosapeptides
US4127530A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel heneicosapeptides, intermediates therefor and pharmaceutical compositions and methods employing said heneicosapeptides
US4312857A (en) * 1977-06-16 1982-01-26 The United States Of America As Represented By The Veterans Administration Novel derivatives of beta-endorphin, intermediates therefor and compositions and methods employing said derivatives
US4127539A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel hexacosapeptides, intermediates therefore and pharmaceutical compositions and methods employing said hexacosapeptides
US4127527A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel pentadecapeptides, intermediates therefor, and compositions and methods employing said pentadecapeptides
US4127540A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel derivatives of δ-endorphins, intermediates therefor, and compositions and methods employing said derivatives
US4127522A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel triacontapeptides, intermediates therefor and pharmaceutical compositions and methods employing said triacontapeptides
ZA783287B (en) * 1977-06-16 1980-01-30 D Coy Novel polypeptides
US4127526A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel tetradecapeptides, intermediates therefor, and compositions and methods employing said tetradecapeptides
US4127537A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel tetracosapeptides, intermediates therefor and pharmaceutical compositions and methods employing said tetracosapeptides
US4127535A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel dipeptides, intermediates therefor, and compositions and methods employing said dipeptides
US4127520A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel nonadecapeptides, intermediates therefor, and compositions and methods employing said nonadecapeptides
US4127529A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel eicosapeptides, intermediates therefor and pharmaceutical compositions and methods employing said eicosapeptides
US4127528A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel derivatives of alpha-endorphin, intermediates therefor and compositions and methods employing said derivatives
US4127541A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel decapeptides, intermediates therefor, and compositions and methods employing said decapeptides
US4127531A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel hexapeptides, intermediates therefor, and compositions and methods employing said hexapeptides
US4127536A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel tricosapeptides, intermediates therefor and pharmaceutical compositions and methods employing said tricosapeptides
US4127534A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel tripeptides, intermediates therefor and pharmaceutical compositions and methods employing said tripeptides
US4127518A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel derivatives of gamma-endorphins, intermediates therefor, and compositions and methods employing said derivatives
US4127533A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel octapeptides, intermediates therefor, and compositions and methods employing said octapeptides
US4139504A (en) * 1977-06-16 1979-02-13 Coy David Howard Novel nonapeptides, intermediates therefor, and compositions and methods employing said nonapeptides
US4105652A (en) * 1977-08-05 1978-08-08 Hoffmann-La Roche Inc. Synthesis of human β-endorphin
US4232008A (en) * 1978-11-17 1980-11-04 Ortho Pharmaceutical Corporation Tetrapeptides and methods
US4116950A (en) * 1978-01-16 1978-09-26 Hoffmann-La Roche Inc. Analogs of human β-endorphin
US4330465A (en) * 1978-03-02 1982-05-18 Hoffmann-La Roche Inc. Novel β-endorphin analogs
US4219468A (en) * 1978-11-13 1980-08-26 Hoffmann-La Roche Inc. Tritiated β-endorphin
US4396606A (en) 1979-11-05 1983-08-02 Addiction Research Foundation Novel polypeptide analgesics
US4250087A (en) * 1979-12-10 1981-02-10 Hoffmann-La Roche Inc. Carboxyl terminus analogs of β-endorphin
JPS56108750A (en) * 1980-02-01 1981-08-28 Takeda Chem Ind Ltd Polypeptide and its preparation
US4438104A (en) 1980-01-03 1984-03-20 Endorphin, Inc. Endorphins having placental or pancreatic origin
US4316895A (en) * 1980-01-03 1982-02-23 Kimball Charles D Endorphins having placental or pancreatic origin
US4350764A (en) * 1980-03-10 1982-09-21 The Regents Of The University Of California Microbiological synthesis of beta endorphin
US4313937A (en) * 1980-08-12 1982-02-02 Tsutomu Oyama Method for producing long-lasting analgesic effects of β-endorphin
GB2111505B (en) * 1981-06-16 1984-09-26 Charles D Kimball Endorphins having placental or pancreatic origin
FR2857873B1 (fr) * 2003-07-21 2006-02-24 Courtage Et De Diffusion Codif Procede et produit cosmetique destines a limiter la croissance des tissus adipeux

Also Published As

Publication number Publication date
MC1137A1 (fr) 1977-11-18
PT66311B (en) 1979-01-17
NO147105C (no) 1983-02-02
ZA771593B (en) 1978-01-25
AR222007A1 (es) 1981-04-15
DE2711487A1 (de) 1977-09-22
FI770835A (pt-PT) 1977-09-18
AR222778A1 (es) 1981-06-30
ATA178877A (de) 1979-07-15
US4038222A (en) 1977-07-26
ES467453A1 (es) 1978-10-16
FR2348912B1 (pt-PT) 1981-02-13
FI63391C (fi) 1983-06-10
LU76963A1 (pt-PT) 1978-06-01
AU514499B2 (en) 1981-02-12
IL51660A0 (en) 1977-05-31
NO147105B (no) 1982-10-25
CH625785A5 (pt-PT) 1981-10-15
NO770941L (no) 1977-09-20
DE2711487C2 (de) 1986-12-11
BE852510A (fr) 1977-09-16
GR63092B (en) 1979-08-13
FR2348912A1 (fr) 1977-11-18
NZ183605A (en) 1980-02-21
DK116177A (da) 1977-09-18
FI63391B (fi) 1983-02-28
IL51660A (en) 1980-02-29
IE44226L (en) 1977-09-17
CA1092602A (en) 1980-12-30
SE436354B (sv) 1984-12-03
PT66311A (en) 1977-04-01
ES456901A1 (es) 1978-07-16
IE44226B1 (en) 1981-09-09
USRE29842E (en) 1978-11-21
DK149203B (da) 1986-03-10
GB1563654A (en) 1980-03-26
NL7702849A (nl) 1977-09-20
SE7703004L (sv) 1977-09-18
JPS62159B2 (pt-PT) 1987-01-06
PH13864A (en) 1980-10-22
AU2329877A (en) 1978-09-21
DK149203C (da) 1986-08-04
JPS52113958A (en) 1977-09-24

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Legal Events

Date Code Title Description
EIH Change in the person of patent owner
ELJ Ceased due to non-payment of the annual fee
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties