AT279626B - Verfahren zur herstellung von neuen 3-(4-r-piperazino)-tert.-amino-propiophenonen, ihren quaternaeren ammoniumverbindungen und salzen - Google Patents
Verfahren zur herstellung von neuen 3-(4-r-piperazino)-tert.-amino-propiophenonen, ihren quaternaeren ammoniumverbindungen und salzenInfo
- Publication number
- AT279626B AT279626B AT00020/69A AT2069A AT279626B AT 279626 B AT279626 B AT 279626B AT 00020/69 A AT00020/69 A AT 00020/69A AT 2069 A AT2069 A AT 2069A AT 279626 B AT279626 B AT 279626B
- Authority
- AT
- Austria
- Prior art keywords
- quaternal
- propiophenones
- piperazino
- tert
- salts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
- C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/52—Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US58435066A | 1966-10-05 | 1966-10-05 | |
US642718A US3538090A (en) | 1966-10-05 | 1967-06-01 | 1-(4-tertiaryaminophenyl)-3-(piperazino)-propanols |
Publications (1)
Publication Number | Publication Date |
---|---|
AT279626B true AT279626B (de) | 1970-03-10 |
Family
ID=27079076
Family Applications (8)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT901167A AT277250B (de) | 1966-10-05 | 1967-10-04 | Verfahren zur Herstellung von neuen 3-(4-R-Piperazino)-tert.amino-propiophenonen, ihren quaternären Ammoniumverbindungen und Salzen |
AT00018/69A AT279625B (de) | 1966-10-05 | 1967-10-04 | Verfahren zur herstellung von neuen 3-(4-r-piperazino)-tert.-amino-propiophenonen, ihren quaternaeren ammoniumverbindungen und salzen |
AT00017/69A AT277264B (de) | 1966-10-05 | 1967-10-04 | Verfahren zur herstellung von neuen 3-(4-r-piperazino)-tert.aminopropiophenonen, ihren quaternaeren ammoniumverbindungen und salzen |
AT00016/69A AT277263B (de) | 1966-10-05 | 1967-10-04 | Verfahren zur herstellung von neuen 3-(4-r-piperazino)-tert.aminopropiophenonen, ihren quaternaeren ammoniumverbindungen und salzen |
AT00019/69A AT277265B (de) | 1966-10-05 | 1967-10-04 | Verfahren zur herstellung von neuen 3-(4-r-piperazino)-tert.aminopropiophenonen, ihren quaternaeren ammoniumverbindungen und salzen |
AT00020/69A AT279626B (de) | 1966-10-05 | 1967-10-04 | Verfahren zur herstellung von neuen 3-(4-r-piperazino)-tert.-amino-propiophenonen, ihren quaternaeren ammoniumverbindungen und salzen |
AT00015/69A AT277262B (de) | 1966-10-05 | 1967-10-04 | Verfahren zur herstellung von neuen 3-(4-r-piperazino)-tert.aminopropiophenonen, ihren quaternaeren ammoniumverbindungen und salzen |
AT04126/69A AT279633B (de) | 1966-10-05 | 1967-10-04 | Verfahren zur herstellung von neuen 3-(4-r-piperazino)-terverfahren zur herstellung von neuen 10,11-dihydrodibenzo<bt.-amino-propiophenonen, ihren quaternaeren ammoniumverbin,f>-azepinderivaten sowie von deren saeureadditionssalzen dungen und salzen und quaternaeren ammoniumverbindungen |
Family Applications Before (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT901167A AT277250B (de) | 1966-10-05 | 1967-10-04 | Verfahren zur Herstellung von neuen 3-(4-R-Piperazino)-tert.amino-propiophenonen, ihren quaternären Ammoniumverbindungen und Salzen |
AT00018/69A AT279625B (de) | 1966-10-05 | 1967-10-04 | Verfahren zur herstellung von neuen 3-(4-r-piperazino)-tert.-amino-propiophenonen, ihren quaternaeren ammoniumverbindungen und salzen |
AT00017/69A AT277264B (de) | 1966-10-05 | 1967-10-04 | Verfahren zur herstellung von neuen 3-(4-r-piperazino)-tert.aminopropiophenonen, ihren quaternaeren ammoniumverbindungen und salzen |
AT00016/69A AT277263B (de) | 1966-10-05 | 1967-10-04 | Verfahren zur herstellung von neuen 3-(4-r-piperazino)-tert.aminopropiophenonen, ihren quaternaeren ammoniumverbindungen und salzen |
AT00019/69A AT277265B (de) | 1966-10-05 | 1967-10-04 | Verfahren zur herstellung von neuen 3-(4-r-piperazino)-tert.aminopropiophenonen, ihren quaternaeren ammoniumverbindungen und salzen |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00015/69A AT277262B (de) | 1966-10-05 | 1967-10-04 | Verfahren zur herstellung von neuen 3-(4-r-piperazino)-tert.aminopropiophenonen, ihren quaternaeren ammoniumverbindungen und salzen |
AT04126/69A AT279633B (de) | 1966-10-05 | 1967-10-04 | Verfahren zur herstellung von neuen 3-(4-r-piperazino)-terverfahren zur herstellung von neuen 10,11-dihydrodibenzo<bt.-amino-propiophenonen, ihren quaternaeren ammoniumverbin,f>-azepinderivaten sowie von deren saeureadditionssalzen dungen und salzen und quaternaeren ammoniumverbindungen |
Country Status (7)
Country | Link |
---|---|
US (2) | US3538090A (de) |
AT (8) | AT277250B (de) |
BE (1) | BE704696A (de) |
ES (1) | ES345694A1 (de) |
FR (3) | FR1549341A (de) |
GB (1) | GB1173369A (de) |
NL (1) | NL6713497A (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3933824A (en) * | 1970-03-06 | 1976-01-20 | Sumitomo Chemical Company, Limited | Piperazinobutyrophenone derivatives |
US4613598A (en) * | 1984-03-13 | 1986-09-23 | Mitsubishi Chemical Industries Limited | Piperazine derivatives and their acid addition salts |
US5380840A (en) * | 1985-09-12 | 1995-01-10 | The Upjohn Company | Triazinylpiperazinyl steroids |
USRE35053E (en) * | 1985-09-12 | 1995-10-10 | The Upjohn Company | Amines useful in producing pharmaceutically active CNS compounds |
US5099019A (en) * | 1985-09-12 | 1992-03-24 | Upjohn Company | Amines useful in producing pharmaceutically active CNS compounds |
GB8603120D0 (en) * | 1986-02-07 | 1986-03-12 | Pfizer Ltd | Anti-dysrhythmia agents |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3317538A (en) * | 1965-10-22 | 1967-05-02 | American Home Prod | 4, 4'-diamino-butyrophenones |
-
1967
- 1967-06-01 US US642718A patent/US3538090A/en not_active Expired - Lifetime
- 1967-09-21 FR FR121719A patent/FR1549341A/fr not_active Expired
- 1967-10-03 GB GB45002/67A patent/GB1173369A/en not_active Expired
- 1967-10-03 ES ES345694A patent/ES345694A1/es not_active Expired
- 1967-10-04 AT AT901167A patent/AT277250B/de not_active IP Right Cessation
- 1967-10-04 AT AT00018/69A patent/AT279625B/de not_active IP Right Cessation
- 1967-10-04 NL NL6713497A patent/NL6713497A/xx unknown
- 1967-10-04 AT AT00017/69A patent/AT277264B/de not_active IP Right Cessation
- 1967-10-04 AT AT00016/69A patent/AT277263B/de not_active IP Right Cessation
- 1967-10-04 AT AT00019/69A patent/AT277265B/de not_active IP Right Cessation
- 1967-10-04 AT AT00020/69A patent/AT279626B/de not_active IP Right Cessation
- 1967-10-04 AT AT00015/69A patent/AT277262B/de not_active IP Right Cessation
- 1967-10-04 AT AT04126/69A patent/AT279633B/de not_active IP Right Cessation
- 1967-10-04 BE BE704696D patent/BE704696A/xx unknown
- 1967-12-19 FR FR132805A patent/FR6943M/fr not_active Expired
- 1967-12-19 FR FR132804A patent/FR7253M/fr not_active Expired
-
1969
- 1969-02-27 US US803068*A patent/US3538091A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AT277262B (de) | 1969-12-29 |
US3538090A (en) | 1970-11-03 |
GB1173369A (en) | 1969-12-10 |
AT279625B (de) | 1970-03-10 |
BE704696A (de) | 1968-04-04 |
AT277265B (de) | 1969-12-29 |
FR6943M (de) | 1969-05-12 |
NL6713497A (de) | 1968-04-08 |
US3538091A (en) | 1970-11-03 |
ES345694A1 (es) | 1969-03-16 |
FR7253M (de) | 1969-09-08 |
AT277264B (de) | 1969-12-29 |
AT279633B (de) | 1970-03-10 |
AT277263B (de) | 1969-12-29 |
FR1549341A (de) | 1968-12-13 |
AT277250B (de) | 1969-12-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ELJ | Ceased due to non-payment of the annual fee |