AR247097A1 - Procedimiento para preparar composiciones farmaceuticas que incluyen copolimeros biologicamente activos como agente activo. - Google Patents

Procedimiento para preparar composiciones farmaceuticas que incluyen copolimeros biologicamente activos como agente activo.

Info

Publication number
AR247097A1
AR247097A1 AR86304301A AR30430186A AR247097A1 AR 247097 A1 AR247097 A1 AR 247097A1 AR 86304301 A AR86304301 A AR 86304301A AR 30430186 A AR30430186 A AR 30430186A AR 247097 A1 AR247097 A1 AR 247097A1
Authority
AR
Argentina
Prior art keywords
copolymers
weight
stimulating
animals
compound
Prior art date
Application number
AR86304301A
Other languages
English (en)
Original Assignee
Univ Emory
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Emory filed Critical Univ Emory
Application granted granted Critical
Publication of AR247097A1 publication Critical patent/AR247097A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/02—Polyalkylene oxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/26—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds
    • C08G65/2618—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds the other compounds containing nitrogen
    • C08G65/2621—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds the other compounds containing nitrogen containing amine groups
    • C08G65/2624—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds the other compounds containing nitrogen containing amine groups containing aliphatic amine groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Polymers & Plastics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR UNA COMPOSICION FARMACEUTICA QUE INCLUYE COMO AGENTE BIOLOGICAMENTE ACTIVO, COPOLIMEROS DE OCHO BLOQUES SELECCIONADOS ENTRE LOS COPOLIMEROS DE OCHO BLOQUES QUE RESPONDEN A LA FORMULA (I), Y COPOLIMEROS DE OCHO BLOQUES DE FORMULA (II), EN DONDE: EL PESO MOLECULAR MEDIO AGREGADO DE LA PORCION DEL COPOLIMERO DE OCHO BLOQUES REPRESENTADO POR POLIOXIPROPILENO ESTACOMPRENDIDA ENTRE 5000 Y 7000 DALTONS; A ES UN NUMERO TAL QUE LA PARTE REPRESENTADA POR POLIOXIETILENO CONSTITUYE ENTRE 10% Y 40% EN PESO DEL COMPUESTO, SIENDO B UN NUMERO TAL QUE LA PARTE POLIOXIPROPILENO DEL PESO MOLECULAR TOTAL DEL COPOLIMERO DE OCHO BLOQUES, CONSTITUYE ENTRE 60% Y 90% EN PESO DEL COMPUESTO, SIENDO DICHA COMPOSICION CAPAZ DE TENER ACTIVIDAD IONOFORA, ESTIMULANDO EL SISTEMA INMUNOLOGICO; INMUNOSUPRIMIENDO A ANIMALES Y AL HOMBRE CONTRA ANTIGENOS Y ESTIMULANDO EL CRECIMIENTO Y LA ACTIVIDAD MOTORA DEL HOMBRE O DE LOS ANIMALES, COMPRENDIENDO ADICIONAR DICHOS COPOLIMEROS DISPERSADOS EN FASE OLEOSA A UNA SOLUCION ACUOSA SALINA QUE COMPRENDE ESTABILIZANTES INCLUYENDO LA FASE OLEOSA, EMULSIFICANTES DE EMULSIONES AGUA EN ACEITE Y HOMOGENEIZAR LA MEZCLA DE AMBAS FASES HASTA OBTENER UNA EMULSION FINA Y ESTABLE.
AR86304301A 1985-06-18 1986-06-18 Procedimiento para preparar composiciones farmaceuticas que incluyen copolimeros biologicamente activos como agente activo. AR247097A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US74591785A 1985-06-18 1985-06-18
US78777085A 1985-10-15 1985-10-15
US87211186A 1986-06-13 1986-06-13

Publications (1)

Publication Number Publication Date
AR247097A1 true AR247097A1 (es) 1994-11-30

Family

ID=27419332

Family Applications (1)

Application Number Title Priority Date Filing Date
AR86304301A AR247097A1 (es) 1985-06-18 1986-06-18 Procedimiento para preparar composiciones farmaceuticas que incluyen copolimeros biologicamente activos como agente activo.

Country Status (13)

Country Link
EP (2) EP0378246B1 (es)
KR (1) KR870700356A (es)
AR (1) AR247097A1 (es)
AT (1) ATE73338T1 (es)
AU (1) AU596986B2 (es)
BR (1) BR8606731A (es)
CA (1) CA1279822C (es)
DE (2) DE3681144D1 (es)
DK (1) DK42187A (es)
HU (1) HUT46539A (es)
IE (1) IE59233B1 (es)
IN (1) IN165421B (es)
WO (1) WO1986007539A1 (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5494660A (en) * 1985-06-18 1996-02-27 Emory University Method for inhibiting microbial binding to surfaces
US5725861A (en) * 1987-04-15 1998-03-10 Effem Gmbh Products and processes for gastric cascade and gastrointestinal disorder treatment with same
WO1990005536A1 (de) * 1988-11-18 1990-05-31 Reinhard Teichmann Erzeugnisse und verfahren zur steigerung von wachstumsgeschwindigkeit und/oder nutzung von futter- oder nahrungsmitteln und/oder resistenz bei tieren und menschen
US6027735A (en) * 1992-07-28 2000-02-22 Effem Gmbh Products and processes for gastric cascade and gastrointestinal disorder treatment with same
US6153193A (en) * 1993-04-28 2000-11-28 Supratek Pharma Inc. Compositions for targeting biological agents
US6277410B1 (en) * 1992-10-08 2001-08-21 Supratek Pharma Inc. Copolymer compositions for oral delivery
US6093391A (en) * 1992-10-08 2000-07-25 Supratek Pharma, Inc. Peptide copolymer compositions
US5800808A (en) 1994-05-24 1998-09-01 Veda Research And Development Co., Ltd. Copolymer-1 improvements in compositions of copolymers
US6221959B1 (en) 1994-11-18 2001-04-24 Supratek Pharma, Inc. Polynucleotide compositions
US6353055B1 (en) 1994-11-18 2002-03-05 Supratek Pharma Inc. Polynucleotide compositions
US5824322A (en) * 1995-08-21 1998-10-20 Cytrx Corporation Compositions and methods for growth promotion
US6054492A (en) * 1996-09-09 2000-04-25 Supratek Pharma Inc. Fluorinated copolymeric pharmaceutical adjuncts
ES2527760T3 (es) 1998-07-23 2015-01-29 Yeda Research And Development Co., Ltd. Tratamiento de enfermedad de Crohn con copolímero 1 y polipéptidos
EP1098902A4 (en) 1998-07-23 2002-07-24 Yeda Res & Dev TREATMENT OF AUTOIMMUNE DISEASES BY COPOLYMER 1 AND SIMILAR COPOLYMERS AND PEPTIDES
US6800287B2 (en) 1998-09-25 2004-10-05 Yeda Research And Development Co., Ltd. Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use
NZ533327A (en) 2001-12-04 2006-11-30 Teva Pharma Processes for the measurement of the potency of glatiramer acetate
HUE028833T2 (en) 2004-09-09 2017-01-30 Yeda Res & Dev Polypeptide mixtures, compositions containing them, process for their preparation, and applications
KR101317131B1 (ko) 2004-09-09 2013-10-10 테바 파마슈티컬 인더스트리즈 리미티드 정제된 브롬화 수소산을 이용한 폴리펩타이드류의 혼합물의제조방법
JP5297653B2 (ja) 2004-10-29 2013-09-25 サンド・アクチエンゲゼルシヤフト グラチラマーの製造法
JP5693463B2 (ja) * 2008-12-04 2015-04-01 ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ 片面または両面に亜鉛メッキされた鋼板から成形品を製造する方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2979528A (en) * 1953-10-19 1961-04-11 Wyandotte Chemicals Corp Nitrogen-containing polyoxyalkylene detergent compositions
US4323467A (en) * 1980-11-24 1982-04-06 Syntex (U.S.A.) Inc. Contact lens cleaning, storing and wetting solutions
DE3572985D1 (en) * 1984-05-11 1989-10-19 Bristol Myers Co Novel bile sequestrant resin and uses
US4567302A (en) * 1984-07-20 1986-01-28 Angus Chemical Polymeric quaternary ammonium salts possessing antimicrobial activity and methods for preparation and use thereof

Also Published As

Publication number Publication date
EP0378246A1 (en) 1990-07-18
EP0378246B1 (en) 1992-03-11
IN165421B (es) 1989-10-14
IE861623L (en) 1986-12-18
DK42187D0 (da) 1987-01-27
ATE73338T1 (de) 1992-03-15
BR8606731A (pt) 1987-08-11
EP0228448B1 (en) 1991-08-28
DK42187A (da) 1987-01-27
IE59233B1 (en) 1994-01-26
HUT46539A (en) 1988-11-28
AU596986B2 (en) 1990-05-24
EP0228448A1 (en) 1987-07-15
DE3681144D1 (de) 1991-10-02
CA1279822C (en) 1991-02-05
WO1986007539A1 (en) 1986-12-31
EP0228448A4 (en) 1987-11-10
AU6123686A (en) 1987-01-13
DE3684333D1 (de) 1992-04-16
KR870700356A (ko) 1987-12-28

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