AR207133A1 - PROCEDURE FOR THE PREPARATION OF 1-PYRIDYLOXY 1-PYRIMIDINYLOXY AND 1-PYRAZINYLOXY-2-HYDROXY-3-AMINO-PROPANE DERIVATIVES - Google Patents

PROCEDURE FOR THE PREPARATION OF 1-PYRIDYLOXY 1-PYRIMIDINYLOXY AND 1-PYRAZINYLOXY-2-HYDROXY-3-AMINO-PROPANE DERIVATIVES

Info

Publication number
AR207133A1
AR207133A1 AR257055A AR25705574A AR207133A1 AR 207133 A1 AR207133 A1 AR 207133A1 AR 257055 A AR257055 A AR 257055A AR 25705574 A AR25705574 A AR 25705574A AR 207133 A1 AR207133 A1 AR 207133A1
Authority
AR
Argentina
Prior art keywords
pyrazinyloxy
pyrimidinyloxy
pyridyloxy
hydroxy
amino
Prior art date
Application number
AR257055A
Other languages
Spanish (es)
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH244473A external-priority patent/CH584209A5/en
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Application granted granted Critical
Publication of AR207133A1 publication Critical patent/AR207133A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/69Two or more oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
AR257055A 1973-02-20 1974-01-01 PROCEDURE FOR THE PREPARATION OF 1-PYRIDYLOXY 1-PYRIMIDINYLOXY AND 1-PYRAZINYLOXY-2-HYDROXY-3-AMINO-PROPANE DERIVATIVES AR207133A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH244473A CH584209A5 (en) 1973-02-20 1973-02-20 3-amino-2-hydroxypropoxy substd. diazines and pyridines - with beta-adrenergic blocking or stimulating activity
FI193/74A FI60391C (en) 1973-02-20 1974-01-23 ANALOGIFICATION OF FRAMSTATION WITH BETA-RECEPTOR-ACTIVE 1-HETEROCYCLYLOXY-3-AMINO-2-PROPANOLFOERING

Publications (1)

Publication Number Publication Date
AR207133A1 true AR207133A1 (en) 1976-09-15

Family

ID=25690464

Family Applications (6)

Application Number Title Priority Date Filing Date
AR257055A AR207133A1 (en) 1973-02-20 1974-01-01 PROCEDURE FOR THE PREPARATION OF 1-PYRIDYLOXY 1-PYRIMIDINYLOXY AND 1-PYRAZINYLOXY-2-HYDROXY-3-AMINO-PROPANE DERIVATIVES
AR257058A AR206801A1 (en) 1973-02-20 1974-01-01 PROCEDURE FOR THE ELABORATION OF DERIVATIVES OF 1-PIRID LOXI-2-HIDROXI-3-AMINO-PROPAN
AR257054A AR208397A1 (en) 1973-02-20 1974-01-01 PROCEDURE FOR THE PREPARATION OF 1-PYRIDYLOXY-2-HYDROXY-3-AMINO-PROPANO1-PIRAZINYLOXY-2-HYDROXY-3-AMINO-PROPANE AND 1-PYRIMIDINYLOXY-2-HYDROXY-3-AMINO-PROPAN COMPOUNDS
AR252438A AR214612A1 (en) 1973-02-20 1974-02-20 PROCEDURE TO PREPARE NEW DERIVATIVES OF 1-PYRIDYLOXY-, 1-PIRAZINYLOXY-, 1-PYRODAZINYLOXY OR 1-PYRIMIDINYLOXY-2-HYDROXY-3-AMINO-PROPANE
AR257057A AR203878A1 (en) 1973-02-20 1974-12-23 PROCEDURE FOR THE PREPARATION OF 1-PYRAZINYLOXY 2-HYDROXY-3-AMINOPROPANE COMPOUNDS
AR264155A AR208043A1 (en) 1973-02-20 1976-01-01 PROCEDURE FOR THE PREPARATION OF DERIVATIVES OF 1-PYRIDYLOXY 1-PYRIMIDINYLOXY AND 1-PIRAZINYLOXY-2-HYDROXY-3-AMINO PROPANE

Family Applications After (5)

Application Number Title Priority Date Filing Date
AR257058A AR206801A1 (en) 1973-02-20 1974-01-01 PROCEDURE FOR THE ELABORATION OF DERIVATIVES OF 1-PIRID LOXI-2-HIDROXI-3-AMINO-PROPAN
AR257054A AR208397A1 (en) 1973-02-20 1974-01-01 PROCEDURE FOR THE PREPARATION OF 1-PYRIDYLOXY-2-HYDROXY-3-AMINO-PROPANO1-PIRAZINYLOXY-2-HYDROXY-3-AMINO-PROPANE AND 1-PYRIMIDINYLOXY-2-HYDROXY-3-AMINO-PROPAN COMPOUNDS
AR252438A AR214612A1 (en) 1973-02-20 1974-02-20 PROCEDURE TO PREPARE NEW DERIVATIVES OF 1-PYRIDYLOXY-, 1-PIRAZINYLOXY-, 1-PYRODAZINYLOXY OR 1-PYRIMIDINYLOXY-2-HYDROXY-3-AMINO-PROPANE
AR257057A AR203878A1 (en) 1973-02-20 1974-12-23 PROCEDURE FOR THE PREPARATION OF 1-PYRAZINYLOXY 2-HYDROXY-3-AMINOPROPANE COMPOUNDS
AR264155A AR208043A1 (en) 1973-02-20 1976-01-01 PROCEDURE FOR THE PREPARATION OF DERIVATIVES OF 1-PYRIDYLOXY 1-PYRIMIDINYLOXY AND 1-PIRAZINYLOXY-2-HYDROXY-3-AMINO PROPANE

Country Status (15)

Country Link
AR (6) AR207133A1 (en)
AT (1) AT335455B (en)
BE (1) BE811274A (en)
CA (1) CA1027131A (en)
CS (1) CS203970B2 (en)
DD (1) DD110041A5 (en)
DE (1) DE2406930A1 (en)
DK (1) DK143501C (en)
ES (2) ES446081A1 (en)
FR (1) FR2218101B1 (en)
GB (1) GB1465946A (en)
IE (1) IE38839B1 (en)
IL (1) IL44202A (en)
LU (1) LU69415A1 (en)
SE (1) SE420834B (en)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4195090A (en) * 1973-02-20 1980-03-25 Ciba-Geigy Corporation 2-(3-Amino-2-hydroxy-propoxy)pyridine derivatives and pharmaceutical compositions therewith
US4000282A (en) * 1974-12-16 1976-12-28 Merck & Co., Inc. 2-(3-tert. butyl or isopropylamino-2-hydroxypropoxy)-3-cyanopyridines
JPS5283759A (en) * 1976-01-01 1977-07-12 Merck & Co Inc Substituted pyridines
US4060601A (en) * 1976-06-15 1977-11-29 Merck & Co., Inc. Certain lower-alkyl amino-2'-hydroxy-propoxy pyridines
US4091104A (en) * 1976-06-15 1978-05-23 Merck & Co., Inc. Substituted (3-loweralkylamino-2-R1 O-propoxy)pyridines, their preparation and use
US4092419A (en) * 1976-06-15 1978-05-30 Merck & Co., Inc. Substituted (3-loweralkylamino-2-R1 O-propoxy)pyridines, their preparation and use
DE2711655A1 (en) * 1977-03-17 1978-09-21 Basf Ag PYRIDINYL-AMINOALKYLAETHER
US4166851A (en) * 1977-05-16 1979-09-04 Merck & Co., Inc. Certain imidazo(1,2a)pyridine derivatives
US4753673A (en) * 1977-07-22 1988-06-28 The Dow Chemical Company Trifluoromethyl pyridinyloxyphenoxy and pyridinylthiophenoxy propanoic acids and propanols and derivatives thereof and methods of herbicidal use
US4144343A (en) * 1978-01-04 1979-03-13 Merck & Co., Inc. Heterocycle substituted (3-loweralkylamino-2-R1 O-propoxy)pyridines
US4279913A (en) * 1978-01-04 1981-07-21 Merck & Co., Inc. Polysubstituted-2-(3-loweralkylamino-2-R1 O-propoxy)pyridines
JPS54106476A (en) * 1978-01-04 1979-08-21 Merck & Co Inc Multiisubstituted 22*33lower alkylaminoo22 r100propoxy*pyridine
US4208416A (en) * 1978-06-27 1980-06-17 Merck & Co., Inc. N-Aralkyl containing cyanopyridines
US4210653A (en) * 1978-06-27 1980-07-01 Merck & Co., Inc. Pyridyloxypropanolamines
DK267779A (en) * 1978-06-27 1979-12-28 Merck & Co Inc PROCEDURE FOR THE PREPARATION OF N-ARALKYLAMINO-PROPOXYCYANOPYRIDINES
US4393212A (en) * 1979-01-29 1983-07-12 Merck & Co., Inc. Certain nicotinic acid esters and corresponding nicotinonitriles
US4294969A (en) * 1979-01-29 1981-10-13 Merck & Co., Inc. Process for producing 2-bromo-3,5-disubstituted pyridines
DD150456A5 (en) * 1979-03-01 1981-09-02 Ciba Geigy Ag PROCESS FOR THE PREPARATION OF DERIVATIVES OF 3-AMINO-1,2-PROPANDIOL
US4281005A (en) 1979-03-05 1981-07-28 Merck & Co., Inc. Novel 2-pyridylimidazole compounds
IT1165040B (en) * 1979-04-23 1987-04-22 Isf Spa ALCOSSIALKILIDENIDRAZINOPIRIDAZIONE AND PROCEDURE FOR THEIR PREPARATION
DE2943774A1 (en) * 1979-10-26 1981-05-14 1000 Berlin Schering Ag Berlin Und Bergkamen SUBSTITUTED PYRIDINE, METHOD FOR THEIR PRODUCTION AND THEIR USE
IL62602A (en) * 1980-05-19 1984-06-29 Labaz Sanofi Nv Pyridoxine derivatives,their preparation and pharmaceutical compositions containing them
FR2502618A1 (en) * 1981-03-25 1982-10-01 Synthelabo PYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
US4517188A (en) * 1983-05-09 1985-05-14 Mead Johnson & Company 1-Pyrimidinyloxy-3-hetaryl-alkylamino-2-propanols
US4598149A (en) * 1984-03-02 1986-07-01 Merck & Co., Inc. 3-amino-2-hydroxypropyl of pyrimidin-4-one useful as antihypertensive, cardioprotective, antiarrythmic, and antianginal agents
US6465467B1 (en) 1999-05-21 2002-10-15 Biovitrum Ab Certain aryl-aliphatic and heteroaryl-aliphatic piperazinyl pyrazines and their use in the treatment of serotonin-related diseases
US7361671B2 (en) * 2001-11-15 2008-04-22 The Institute For Pharmaceutical Discovery, Inc. Substituted heteroarylalkanoic acids
ATE454383T1 (en) 2002-06-19 2010-01-15 Biovitrum Ab Publ NEW COMPOUNDS, THEIR USE AND PRODUCTION
US20070060748A1 (en) * 2002-11-27 2007-03-15 Hamilton Gregory S Compounds with mixed pde-inhibitory and beta-adrenergic antagonist or partial agonist activity for treatment of heart failure
US20080033020A1 (en) * 2004-07-23 2008-02-07 Darren Mansfield 3-Pyridinylethylbenzamide Derivatives as Fungicides
US20110183980A1 (en) * 2009-09-21 2011-07-28 Conn P Jeffrey O-benzyl nicotinamide analogs as mglur5 positive allosteric modulators

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1001631A (en) * 1972-05-05 1976-12-14 Merck Sharp And Dohme (I.A.) Corp. 2-(3-substituted amino-2-hydroxy-propoxy)-3-substituted pyrazines and method for preparation

Also Published As

Publication number Publication date
DK143501B (en) 1981-08-31
AR206801A1 (en) 1976-08-23
FR2218101B1 (en) 1977-07-15
IL44202A0 (en) 1974-06-30
AR208397A1 (en) 1976-12-27
IE38839B1 (en) 1978-06-07
LU69415A1 (en) 1975-12-09
CS203970B2 (en) 1981-03-31
IE38839L (en) 1974-08-20
ATA133074A (en) 1976-07-15
AR203878A1 (en) 1975-10-31
BE811274A (en) 1974-08-19
DD110041A5 (en) 1974-12-05
FR2218101A1 (en) 1974-09-13
DK143501C (en) 1982-02-22
AR214612A1 (en) 1979-07-13
ES446083A1 (en) 1977-09-16
DE2406930A1 (en) 1974-08-22
SE420834B (en) 1981-11-02
GB1465946A (en) 1977-03-02
AR208043A1 (en) 1976-11-22
CA1027131A (en) 1978-02-28
AT335455B (en) 1977-03-10
ES446081A1 (en) 1977-06-16
IL44202A (en) 1978-10-31

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