AR194952A1 - PROCEDURE FOR THE MANUFACTURE OF A DERIVATIVE OF PROSTANOIC ACID - Google Patents

PROCEDURE FOR THE MANUFACTURE OF A DERIVATIVE OF PROSTANOIC ACID

Info

Publication number
AR194952A1
AR194952A1 AR241955A AR24195572A AR194952A1 AR 194952 A1 AR194952 A1 AR 194952A1 AR 241955 A AR241955 A AR 241955A AR 24195572 A AR24195572 A AR 24195572A AR 194952 A1 AR194952 A1 AR 194952A1
Authority
AR
Argentina
Prior art keywords
derivative
procedure
manufacture
prostanoic acid
prostanoic
Prior art date
Application number
AR241955A
Other languages
Spanish (es)
Original Assignee
Ici Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB3967272A external-priority patent/GB1348036A/en
Application filed by Ici Ltd filed Critical Ici Ltd
Application granted granted Critical
Publication of AR194952A1 publication Critical patent/AR194952A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/40Radicals substituted by oxygen atoms
    • C07D307/42Singly bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0016Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0033Analogues having the carboxyl group in the side-chains replaced by other functional groups containing sulfur
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0041Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10Oxygen atoms
    • C07D309/12Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006Esters of acyclic acids which can have further substituents on alkyl
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/535Organo-phosphoranes
    • C07F9/5352Phosphoranes containing the structure P=C-

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AR241955A 1971-05-11 1972-05-11 PROCEDURE FOR THE MANUFACTURE OF A DERIVATIVE OF PROSTANOIC ACID AR194952A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1413971 1971-05-11
GB3967272A GB1348036A (en) 1970-05-15 1972-01-05 Transistorized vertical deflection circuit

Publications (1)

Publication Number Publication Date
AR194952A1 true AR194952A1 (en) 1973-08-30

Family

ID=26235892

Family Applications (4)

Application Number Title Priority Date Filing Date
AR241955A AR194952A1 (en) 1971-05-11 1972-05-11 PROCEDURE FOR THE MANUFACTURE OF A DERIVATIVE OF PROSTANOIC ACID
AR245420A AR200484A1 (en) 1971-05-11 1972-11-30 PROCEDURE FOR THE MANUFACTURE OF A DERIVATIVE OF PROSTANOIC ACID
AR245418A AR197100A1 (en) 1971-05-11 1972-11-30 PROCEDURE FOR THE MANUFACTURE OF A DERIVATIVE OF PROSTANOIC ACID
AR245419A AR197101A1 (en) 1971-05-11 1972-11-30 PROCEDURE FOR THE MANUFACTURE OF A DERIVATIVE OF PROSTANOIC ACID

Family Applications After (3)

Application Number Title Priority Date Filing Date
AR245420A AR200484A1 (en) 1971-05-11 1972-11-30 PROCEDURE FOR THE MANUFACTURE OF A DERIVATIVE OF PROSTANOIC ACID
AR245418A AR197100A1 (en) 1971-05-11 1972-11-30 PROCEDURE FOR THE MANUFACTURE OF A DERIVATIVE OF PROSTANOIC ACID
AR245419A AR197101A1 (en) 1971-05-11 1972-11-30 PROCEDURE FOR THE MANUFACTURE OF A DERIVATIVE OF PROSTANOIC ACID

Country Status (26)

Country Link
JP (1) JPS5611699B1 (en)
AR (4) AR194952A1 (en)
AT (4) AT328103B (en)
AU (1) AU462755B2 (en)
BE (1) BE783292A (en)
CA (1) CA1077033A (en)
CH (3) CH590223A5 (en)
CS (1) CS192456B2 (en)
DD (1) DD99155A5 (en)
DE (1) DE2223365C3 (en)
DK (1) DK134598B (en)
EG (1) EG10752A (en)
ES (1) ES402627A1 (en)
FI (1) FI63221C (en)
FR (1) FR2137712A1 (en)
HK (1) HK50176A (en)
HU (1) HU166717B (en)
IE (1) IE37602B1 (en)
IL (1) IL39376A (en)
KE (1) KE2634A (en)
NL (1) NL164272C (en)
NO (1) NO139521C (en)
SE (4) SE399705B (en)
SU (1) SU662007A3 (en)
YU (1) YU35876B (en)
ZM (1) ZM8172A1 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4304907A (en) * 1972-05-10 1981-12-08 The Upjohn Company Bicyclo lactone intermediates for prostaglandin analogs
DD118856A5 (en) * 1972-11-08 1976-03-20
US3968144A (en) * 1973-05-21 1976-07-06 The Upjohn Company 5-Oxa-11-deoxy phenyl- and phenoxy-substituted prostalandin E1 analogs
US3966795A (en) * 1973-05-21 1976-06-29 The Upjohn Company 5-Oxa-11-deoxyphenyl- and phenoxy-substituted prostaglandin F1.sub.α analogs
US4387241A (en) * 1974-11-01 1983-06-07 American Cyanamid Company Novel 16-aryloxy-17,18,19,20-tetranorprostanoic acids and derivatives
US4149006A (en) * 1977-01-24 1979-04-10 G. D. Searle & Co. Prostaglandin derivatives having alkynyl, hydroxy and aryloxy junctions in the 2β side chain
US4191774A (en) * 1978-01-18 1980-03-04 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara R.T. Novel 17-aza-PGF2α derivatives and pharmaceutical compositions containing the same
US4228296A (en) * 1979-01-24 1980-10-14 American Cyanamid Company Novel 16-aryloxy-17,18,19,20-tetranorprostanoic acids and derivatives
US4929740A (en) * 1984-10-09 1990-05-29 Syntex (U.S.A.) Inc. Process for making 16-phenoxy- and 16-(substituted phenoxy)-prostatrienoic acid derivatives
CS264861B1 (en) * 1986-12-12 1989-09-12 Kral Josef Agent for cow natality increase
CS265947B1 (en) * 1987-06-16 1989-11-14 Kral Josef Means for farming animals' ovarian functions control
US5565492A (en) * 1988-07-18 1996-10-15 Alcon Laboratories, Inc. Prostaglandin combinations in glaucoma therapy
CS276003B6 (en) * 1988-09-28 1992-03-18 Spolana method of production of (+)-isomer of cloprostenol
US5352708A (en) * 1992-09-21 1994-10-04 Allergan, Inc. Non-acidic cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents
US5688819A (en) * 1992-09-21 1997-11-18 Allergan Cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents
US5510383A (en) * 1993-08-03 1996-04-23 Alcon Laboratories, Inc. Use of cloprostenol, fluprostenol and their salts and esters to treat glaucoma and ocular hypertension
US6531504B2 (en) * 2001-05-17 2003-03-11 Allergan, Inc. Prostanoic acid derivatives as agents for lowering intraocular pressure
NZ585517A (en) * 2007-11-09 2012-08-31 Allergan Inc 5-[3-(2-Alkyl-cyclopentyl)-propyl]thiophene-2-carboxylic acid derivatives as prostaglandin analogues, and pharmaceutical uses thereof

Also Published As

Publication number Publication date
NL7206361A (en) 1972-11-14
AU4202472A (en) 1973-11-15
FR2137712A1 (en) 1972-12-29
SE7504337L (en) 1975-04-15
IL39376A0 (en) 1972-07-26
CS192456B2 (en) 1979-08-31
YU125072A (en) 1981-02-28
CH590223A5 (en) 1977-07-29
ATA539173A (en) 1975-05-15
IL39376A (en) 1975-07-28
DK134598B (en) 1976-12-06
NO139521B (en) 1978-12-18
ATA419172A (en) 1976-03-15
AT328103B (en) 1976-03-10
JPS5611699B1 (en) 1981-03-16
KE2634A (en) 1976-06-11
SE399705B (en) 1978-02-27
IE37602B1 (en) 1977-08-31
ATA538973A (en) 1975-05-15
HK50176A (en) 1976-08-13
AR200484A1 (en) 1974-11-15
FR2137712B1 (en) 1976-04-16
FI63221C (en) 1983-05-10
EG10752A (en) 1976-05-31
DE2223365A1 (en) 1972-12-07
AT328104B (en) 1976-03-10
NO139521C (en) 1979-03-28
AR197101A1 (en) 1974-03-15
AU462755B2 (en) 1975-07-03
ZM8172A1 (en) 1973-01-22
CA1077033A (en) 1980-05-06
CH596166A5 (en) 1978-02-28
NL164272C (en) 1980-12-15
CH596165A5 (en) 1978-02-28
DE2223365C3 (en) 1981-06-04
SE7504335L (en) 1975-04-15
NL164272B (en) 1980-07-15
DE2223365B2 (en) 1980-07-31
HU166717B (en) 1975-05-28
DK134598C (en) 1977-05-16
ATA539073A (en) 1975-05-15
AT328105B (en) 1976-03-10
BE783292A (en) 1972-11-10
AT333447B (en) 1976-11-25
SE7504336L (en) 1975-04-15
SU662007A3 (en) 1979-05-05
DD99155A5 (en) 1973-07-20
ES402627A1 (en) 1975-11-01
FI63221B (en) 1983-01-31
YU35876B (en) 1981-08-31
AR197100A1 (en) 1974-03-15
IE37602L (en) 1972-11-11

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