AR122228A1 - Composiciones de spray nasal antiviral y viricida y métodos de tratamiento relacionados - Google Patents

Composiciones de spray nasal antiviral y viricida y métodos de tratamiento relacionados

Info

Publication number
AR122228A1
AR122228A1 ARP210101073A ARP210101073A AR122228A1 AR 122228 A1 AR122228 A1 AR 122228A1 AR P210101073 A ARP210101073 A AR P210101073A AR P210101073 A ARP210101073 A AR P210101073A AR 122228 A1 AR122228 A1 AR 122228A1
Authority
AR
Argentina
Prior art keywords
approximately
mass
concentration
composition
nasal spray
Prior art date
Application number
ARP210101073A
Other languages
English (en)
Inventor
Gustavo Ferrer
Original Assignee
Ferrer Medical Innovations Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrer Medical Innovations Llc filed Critical Ferrer Medical Innovations Llc
Publication of AR122228A1 publication Critical patent/AR122228A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Botany (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Otolaryngology (AREA)
  • Biochemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Composiciones de spray nasal antiviral y viricida para el tratamiento o prevención de infecciones virales, tales como influenza A y B, coronavirus, incluyendo sin carácter taxativo, COVID-19, y rinovirus, junto con métodos de tratamiento relacionados. Ciertas composiciones de acuerdo con realizaciones preferentes de la invención pueden comprender clorfeniramina, xilitol y otros ingredientes inactivos tales como aloe vera y/o extracto de semillas de uva. Asimismo, las composiciones pueden comprender un corticosteroide seleccionado del grupo conformado por mometasona, propionato de fluticasona, furoato de fluticasona, acetónido de triamcinolona y/o glucocorticoide budesónida, en una concentración de entre 0,01% y 3% aproximadamente por masa. Los métodos de tratamiento relacionados comprenden la administración de una composición del spray nasal dentro de los conductos nasales del paciente mediante 1 a 2 pulverizaciones de la composición cada seis, ocho o doce horas. Reivindicación 1: Una composición de spray nasal antiviral y viricida, caracterizada porque comprende: A) maleato de clorfeniramina en una concentración de entre 0,01% y 10% aproximadamente por masa; B) xilitol en una concentración de entre 10% y 15% aproximadamente por masa; y C) extracto de semillas de uva en una concentración de entre 0,01% y 3% aproximadamente por masa; estando dicho maleato de clorfeniramina en una concentración de entre 0,25% y 4% aproximadamente por masa; comprendiendo dicha composición un corticosteroide seleccionado del grupo conformado por mometasona, propionato de fluticasona, furoato de fluticasona, acetónido de triamcinolona y/o glucocorticoide budesónida, en una concentración de entre 0,01% y 3% aproximadamente por masa; siendo dicho corticosteroide preferentemente propionato de fluticasona en una concentración de entre 0,03% y 1,0% aproximadamente por masa; siendo dicha composición utilizada en el tratamiento de infecciones virales seleccionadas a partir del grupo conformado por resfríos, influenza A y B, coronavirus, especialmente COVID-19 y rinovirus.
ARP210101073A 2020-04-24 2021-04-21 Composiciones de spray nasal antiviral y viricida y métodos de tratamiento relacionados AR122228A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063015415P 2020-04-24 2020-04-24
US16/924,683 US10874650B1 (en) 2020-04-24 2020-07-09 Antiviral and virucidal nasal spray compositions and related treatment methods

Publications (1)

Publication Number Publication Date
AR122228A1 true AR122228A1 (es) 2022-08-31

Family

ID=74039572

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP210101073A AR122228A1 (es) 2020-04-24 2021-04-21 Composiciones de spray nasal antiviral y viricida y métodos de tratamiento relacionados

Country Status (9)

Country Link
US (1) US10874650B1 (es)
EP (1) EP3993788A4 (es)
CN (1) CN115605203A (es)
AR (1) AR122228A1 (es)
AU (1) AU2020443548B2 (es)
BR (1) BR112022021556A2 (es)
CA (1) CA3176035C (es)
MX (1) MX2022013169A (es)
WO (1) WO2021216118A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11426392B1 (en) * 2021-04-14 2022-08-30 Ferrer Medical Innovations, Llc. Antiviral and virucidal lung nebulizer compositions and related treatment methods

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3153797A (en) * 1996-06-04 1998-01-05 Procter & Gamble Company, The A nasal spray containing an intranasal steroid and an antihistamine
US6054143A (en) * 1998-03-24 2000-04-25 Jones; Alonzo H. Xylitol delivery
US20040235807A1 (en) * 2003-05-21 2004-11-25 Weinrich Karl P. Formulations including a topical decongestant and a topical corticosteroid suitable for nasal administration and method for treating obstructive sleep apnea
AU2006226887A1 (en) * 2005-03-23 2006-09-28 Elan Pharma International Limited Nanoparticulate corticosteroid and antihistamine formulations
US20080058421A1 (en) * 2006-09-05 2008-03-06 John Alex Lopes Compositions for cleaning and disinfecting nasal tract and sinus cavity
CN103239446B (zh) * 2013-05-13 2014-11-12 中国科学院武汉病毒研究所 一种马来酸氯苯那敏在制备治疗或预防流感病毒药物中的应用
EP3965886A4 (en) * 2019-02-15 2023-06-07 Ferrer Medical Innovations, LLC NASAL SPRAY COMPOSITIONS AND RELATED METHODS OF TREATMENT

Also Published As

Publication number Publication date
EP3993788A4 (en) 2023-08-02
AU2020443548B2 (en) 2023-03-16
US10874650B1 (en) 2020-12-29
WO2021216118A1 (en) 2021-10-28
BR112022021556A2 (pt) 2022-12-06
CN115605203A (zh) 2023-01-13
CA3176035C (en) 2023-09-12
EP3993788A1 (en) 2022-05-11
CA3176035A1 (en) 2021-10-28
AU2020443548A1 (en) 2022-11-10
MX2022013169A (es) 2022-11-30

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