AR120259A1 - AAV3B VARIANTS WITH ENHANCED PRODUCTION YIELD AND LIVER TROPISM - Google Patents

AAV3B VARIANTS WITH ENHANCED PRODUCTION YIELD AND LIVER TROPISM

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Publication number
AR120259A1
AR120259A1 ARP200102894A ARP200102894A AR120259A1 AR 120259 A1 AR120259 A1 AR 120259A1 AR P200102894 A ARP200102894 A AR P200102894A AR P200102894 A ARP200102894 A AR P200102894A AR 120259 A1 AR120259 A1 AR 120259A1
Authority
AR
Argentina
Prior art keywords
production yield
enhanced production
liver tropism
aav3b
variants
Prior art date
Application number
ARP200102894A
Other languages
Spanish (es)
Inventor
James M Wilson
Qiang Wang
Original Assignee
Univ Pennsylvania
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pennsylvania filed Critical Univ Pennsylvania
Publication of AR120259A1 publication Critical patent/AR120259A1/en

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  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

En el presente documento se presentan cápsides de AAV y rAAV que las comprenden. En una realización, vectores que emplean una cápside de AAV descrita exhiben transducción aumentada en un tejido seleccionado en comparación con un AAV de la técnica anterior.Presented herein are AAV and rAAV capsids comprising them. In one embodiment, vectors employing a disclosed AAV capsid exhibit increased transduction in a selected tissue compared to a prior art AAV.

ARP200102894A 2019-10-21 2020-10-20 AAV3B VARIANTS WITH ENHANCED PRODUCTION YIELD AND LIVER TROPISM AR120259A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201962924112P 2019-10-21 2019-10-21

Publications (1)

Publication Number Publication Date
AR120259A1 true AR120259A1 (en) 2022-02-09

Family

ID=80782191

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP200102894A AR120259A1 (en) 2019-10-21 2020-10-20 AAV3B VARIANTS WITH ENHANCED PRODUCTION YIELD AND LIVER TROPISM

Country Status (1)

Country Link
AR (1) AR120259A1 (en)

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