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Priority claimed from PCT/US2020/030273external-prioritypatent/WO2020223232A1/en
Publication of EA202192955A1publicationCriticalpatent/EA202192955A1/en
Micro-Organisms Or Cultivation Processes Thereof
(AREA)
Abstract
В данном документе предложены новые капсиды AAV и rAAV, содержащий их. В одном варианте реализации изобретения векторы, использующие новый капсид AAV, демонстрируют повышенную трансдукцию выбранной ткани-мишени по сравнению с AAV предшествующего уровня техники.This document proposes new AAV capsids and rAAV containing them. In one embodiment of the invention, vectors using the new AAV capsid exhibit increased transduction of the selected target tissue compared to prior art AAVs.
EA202192955A2019-10-212020-04-28
NEW AAV CAPSIDS AND COMPOSITIONS CONTAINING THEM
EA202192955A1
(en)
Peptide-modified hybrid recombinant adeno-associated virus serotype between aav9 and aavrh74 with reduced liver tropism and increased muscle transduction
CRYSTALLINE (R) -5-CARBAMOILPIRIDIN-3-IL-2-METHYL-4- (3- (TRIFLUOROMETOXY) BENZYL) PIPERAZIN-1-CARBOXYLATE, ITS COMPOSITIONS AND METHODS OF APPLICATION