AR117633A1 - Activadores de la vía inducible del gen “rig-i” del ácido retinoico y métodos de uso de los mismos - Google Patents

Activadores de la vía inducible del gen “rig-i” del ácido retinoico y métodos de uso de los mismos

Info

Publication number
AR117633A1
AR117633A1 ARP190102282A ARP190102282A AR117633A1 AR 117633 A1 AR117633 A1 AR 117633A1 AR P190102282 A ARP190102282 A AR P190102282A AR P190102282 A ARP190102282 A AR P190102282A AR 117633 A1 AR117633 A1 AR 117633A1
Authority
AR
Argentina
Prior art keywords
rig
activators
gene
methods
same
Prior art date
Application number
ARP190102282A
Other languages
English (en)
Original Assignee
Kineta Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kineta Inc filed Critical Kineta Inc
Publication of AR117633A1 publication Critical patent/AR117633A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D419/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms
    • C07D419/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/66—Nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente está dirigida a compuestos de la fórmula (1), que son activadores de la ruta RIG-I.
ARP190102282A 2018-08-09 2019-08-09 Activadores de la vía inducible del gen “rig-i” del ácido retinoico y métodos de uso de los mismos AR117633A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201862716830P 2018-08-09 2018-08-09

Publications (1)

Publication Number Publication Date
AR117633A1 true AR117633A1 (es) 2021-08-18

Family

ID=67766345

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP190102282A AR117633A1 (es) 2018-08-09 2019-08-09 Activadores de la vía inducible del gen “rig-i” del ácido retinoico y métodos de uso de los mismos

Country Status (6)

Country Link
US (1) US20200071316A1 (es)
AR (1) AR117633A1 (es)
CA (1) CA3051422A1 (es)
TW (1) TW202021956A (es)
UY (1) UY38332A (es)
WO (1) WO2020033782A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2021315786A1 (en) * 2020-07-31 2023-02-23 Children's Healthcare Of Atlanta, Inc. Cystic fibrosis transmembrane conductance regulator (CFTR) modulators, pharmaceutical compositions, and uses thereof
KR20220153888A (ko) * 2021-05-12 2022-11-21 에이치케이이노엔 주식회사 신규한 벤조티아졸 유도체, 이의 제조방법 및 이의 간질환 예방 또는 치료 용도
EP4334298A1 (en) 2021-06-14 2024-03-13 Scorpion Therapeutics, Inc. Urea derivatives which can be used to treat cancer
WO2023201014A1 (en) * 2022-04-15 2023-10-19 Vanderbilt University Benzothiazole-phenylsulfonyl-piperidine analogs as activators of n-acylphosphatidylethanolamine hydrolyzing phospholipase d

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106456615B (zh) * 2014-05-09 2020-10-27 奇尼塔公司 抗病毒化合物、医药组合物及其使用方法

Also Published As

Publication number Publication date
US20200071316A1 (en) 2020-03-05
WO2020033782A1 (en) 2020-02-13
UY38332A (es) 2020-03-31
TW202021956A (zh) 2020-06-16
CA3051422A1 (en) 2020-02-09

Similar Documents

Publication Publication Date Title
AR117633A1 (es) Activadores de la vía inducible del gen “rig-i” del ácido retinoico y métodos de uso de los mismos
CO2021016018A2 (es) Inhibidores de tead y usos de los mismos referencia cruzada a solicitudes relacionadas
CO2021016015A2 (es) Inhibidores de tead y usos de los mismos referencia cruzada a solicitudes relacionadas
CL2022001670A1 (es) Inhibidores de proteínas kras mutantes
CL2020002342A1 (es) Uso de anticuerpos anti-il-36r para el tratamiento de la psoriasis pustulosa generalizada
TWD204257S (zh) 絞車(一)
CL2020002540A1 (es) Anticuerpos anti-hla-g y utilización de los mismos
UY36886A (es) Compuesto para usar en composiciones que cambian de color
CL2018000111A1 (es) Microorganismos para la producción de putrescina u ornitina y procedimiento para la producción de putrescina u ornitina usando los mismos
EA202092692A1 (ru) Аналоги рапамицина и их применения
UY38759A (es) Tienilhidroxiisoxazolinas y derivados de las mismas
CL2020002217A1 (es) Uso de alcoxipirazoles como inhibidores de la nitrificación
TWD195578S (zh) 引擎作動發電機
CL2022000807A1 (es) Compuesto bicíclico y uso del mismo
MX2017013126A (es) Placa de iluminación.
CO2023015915A2 (es) Anticuerpos anti-ccr8
CL2020003214A1 (es) Nuevos derivados de isoxazolil éter como pam de gaba a alfa5
CO2023008475A2 (es) Inhibidores de enzimas
CL2020001818A1 (es) Compuestos de sililetinilo hetarilo como inhibidores de la nitrificación.
UY38331A (es) Activadores de la vía inducible del gen "rig-i" del ácido retinoico y métodos de uso de los mismos
CL2023001492A1 (es) Anticuerpos anti-ly6g6d y métodos de uso.
CL2021002501A1 (es) Compuestos novedosos y métodos de uso de los mismos.
CO2022007621A2 (es) Nuevos inhibidores de braf como rompedores de la paradoja
CL2022001594A1 (es) Tiofenocarboxamidas sustituidas y sus derivados
CL2022001456A1 (es) Tiofenocarboxamidas sustituidas y sus derivados

Legal Events

Date Code Title Description
FB Suspension of granting procedure