AR104577A2 - METHODS TO TREAT OR REDUCE THE LIKELIHOOD OF ACQUIRING SYMPTOMS OR DISEASES DUE TO MENOPAUSE - Google Patents
METHODS TO TREAT OR REDUCE THE LIKELIHOOD OF ACQUIRING SYMPTOMS OR DISEASES DUE TO MENOPAUSEInfo
- Publication number
- AR104577A2 AR104577A2 ARP160101337A ARP160101337A AR104577A2 AR 104577 A2 AR104577 A2 AR 104577A2 AR P160101337 A ARP160101337 A AR P160101337A AR P160101337 A ARP160101337 A AR P160101337A AR 104577 A2 AR104577 A2 AR 104577A2
- Authority
- AR
- Argentina
- Prior art keywords
- steroid precursor
- administered
- sex steroid
- menopause
- diseases due
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
Abstract
Reivindicación 1: Un método para tratar y/o reducir la probabilidad de adquirir los síntomas o enfermedades debidos a la menopausia, en mujeres postmenopáusicas, caracterizado porque dicho método comprende administrar un precursor de esteroides sexuales seleccionado del grupo formado por dehidroepiandrosterona, sulfato de dehidroepiandrosterona, androst-5-en-3b,17b-diol y 4-androsten-3,17-diona a un paciente que necesita de dicho tratamiento, en donde dicho precursor de esteroides sexuales es administrada como una cantidad terapéutica que incrementa el nivel de metabolitos de andrógeno en la circulación sin incrementar el nivel en circulación de estradiol por encima de los valores observados en mujeres postmenopáusicas normales con el fin de evitar el riesgo de cáncer de mama y útero. Reivindicación 2: El método de la reivindicación 1, caracterizado porque el precursor de esteroides sexuales es administrado sobre la piel. Reivindicación 3: El método de la reivindicación 1, caracterizado porque el precursor de esteroides sexuales es administrado por vía intravaginal. Reivindicación 4: El método de la reivindicación 1, caracterizado porque el precursor de esteroides sexuales es administrado por vía oral. Reivindicación 24: El método de las reivindicaciones 21 y 22, caracterizado porque el modulador selectivo del receptor de estrógeno presenta la estructura química de fórmula (1).Claim 1: A method for treating and / or reducing the probability of acquiring symptoms or diseases due to menopause, in postmenopausal women, characterized in that said method comprises administering a sexual steroid precursor selected from the group consisting of dehydroepiandrosterone, dehydroepiandrosterone sulfate, androst-5-en-3b, 17b-diol and 4-androsten-3.17-dione a patient in need of such treatment, wherein said sex steroid precursor is administered as a therapeutic amount that increases the metabolite level of androgen in the circulation without increasing the level of estradiol in circulation above the values observed in normal postmenopausal women in order to avoid the risk of breast and uterine cancer. Claim 2: The method of claim 1, characterized in that the sex steroid precursor is administered on the skin. Claim 3: The method of claim 1, characterized in that the sex steroid precursor is administered intravaginally. Claim 4: The method of claim 1, characterized in that the sex steroid precursor is administered orally. Claim 24: The method of claims 21 and 22, characterized in that the selective estrogen receptor modulator has the chemical structure of formula (1).
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US96427007P | 2007-08-10 | 2007-08-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR104577A2 true AR104577A2 (en) | 2017-08-02 |
Family
ID=43618448
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP160101337A AR104577A2 (en) | 2007-08-10 | 2016-05-10 | METHODS TO TREAT OR REDUCE THE LIKELIHOOD OF ACQUIRING SYMPTOMS OR DISEASES DUE TO MENOPAUSE |
Country Status (3)
Country | Link |
---|---|
AR (1) | AR104577A2 (en) |
UA (1) | UA100701C2 (en) |
ZA (1) | ZA201000874B (en) |
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2008
- 2008-08-08 UA UAA201002703A patent/UA100701C2/en unknown
-
2010
- 2010-02-05 ZA ZA201000874A patent/ZA201000874B/en unknown
-
2016
- 2016-05-10 AR ARP160101337A patent/AR104577A2/en unknown
Also Published As
Publication number | Publication date |
---|---|
UA100701C2 (en) | 2013-01-25 |
ZA201000874B (en) | 2010-10-27 |
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