AR101240A1 - Formas cristalinas de (2r,5s,13ar)-8-hidroxi-7,9-dioxo-n-(2,4,6-trifluorobencil)-2,3,4,5,7,9,13,13a-octahidro-2,5-metanopirido[1,2,4,5]pirazino[2,1-b][1,3]oxazapina-10-carboxamida
- Google Patents
Formas cristalinas de (2r,5s,13ar)-8-hidroxi-7,9-dioxo-n-(2,4,6-trifluorobencil)-2,3,4,5,7,9,13,13a-octahidro-2,5-metanopirido[1,2,4,5]pirazino[2,1-b][1,3]oxazapina-10-carboxamida
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Formas cristalinas y co-cristales de (2R,5S,13aR)-8-hidroxi-7,9-dioxo-N-(2,4,6-trifluorobencil)-2,3,4,5,7,9,13,13a-octahidro-2,5-metanopirido[1,2,4,5]pirazino[2,1-b][1,3]oxazapina-10-carboxamida, las formulaciones farmacéuticas, y los usos terapéuticos de las mismas. También se relaciona con formas cristalinas de (2R,5S,13aR)-7,9-dioxo-10-((2,4,6-trifluorobencil)carbamoil)-2,3,4,5,7,9,13,13a-octahidro-2,5-metanopirido[1,2,4,5]pirazino[2,1-b][1,3]oxazepin-8-olato de sodio Forma I.
ARP150101952A2014-06-202015-06-18Formas cristalinas de (2r,5s,13ar)-8-hidroxi-7,9-dioxo-n-(2,4,6-trifluorobencil)-2,3,4,5,7,9,13,13a-octahidro-2,5-metanopirido[1,2,4,5]pirazino[2,1-b][1,3]oxazapina-10-carboxamida
AR101240A1
(es)
Formas cristalinas de (2r,5s,13ar)-8-hidroxi-7,9-dioxo-n-(2,4,6-trifluorobencil)-2,3,4,5,7,9,13,13a-octahidro-2,5-metanopirido[1,2,4,5]pirazino[2,1-b][1,3]oxazapina-10-carboxamida
Compuestos bicíclicos fusionados, sus composiciones y su uso para el tratamiento de enfermedades relacionadas con la modulación del receptor x farnesoide (fxr).
Formas cristalinas de (2r,5s,13ar)-8-hidroxi-7,9-dioxo-n-(2,4,6-trifluorobencil)-2,3,4,5,7,9,13,13a-octahidro-2,5-metanopirido[1,2,4,5]pirazino[2,1-b][1,3]oxazapina-10-carboxamida