AR096390A1 - COMPOSITIONS OF ARNi DE SERPINA1 AND ITS METHODS OF USE - Google Patents

COMPOSITIONS OF ARNi DE SERPINA1 AND ITS METHODS OF USE

Info

Publication number
AR096390A1
AR096390A1 ARP140102031A ARP140102031A AR096390A1 AR 096390 A1 AR096390 A1 AR 096390A1 AR P140102031 A ARP140102031 A AR P140102031A AR P140102031 A ARP140102031 A AR P140102031A AR 096390 A1 AR096390 A1 AR 096390A1
Authority
AR
Argentina
Prior art keywords
serpina1
methods
rnai agents
arni
compositions
Prior art date
Application number
ARP140102031A
Other languages
Spanish (es)
Inventor
Bettencourt Brian
Sehgal Alfica
Charisse Klaus
Original Assignee
Alnylam Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alnylam Pharmaceuticals Inc filed Critical Alnylam Pharmaceuticals Inc
Publication of AR096390A1 publication Critical patent/AR096390A1/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Se relaciona con agentes de ARNi, por ejemplo, agentes de ARNi de doble hebra, que se dirigen contra el gen de Serpina1, y métodos para usar dichos agentes de ARNi para inhibir la expresión de Serpina1 y métodos para tratar a sujetos que tienen una enfermedad asociada a Serpina1, tal como un trastorno de hígado. Composición farmacéutica; vector; célula; método para reducir la acumulación de Serpina1.It relates to RNAi agents, for example, double-stranded RNAi agents, which are directed against the Serpina1 gene, and methods for using said RNAi agents to inhibit Serpina1 expression and methods for treating subjects who have a disease. associated with Serpina1, such as a liver disorder. Pharmaceutical composition; vector; cell; method to reduce the accumulation of Serpine1.

ARP140102031A 2013-05-22 2014-05-22 COMPOSITIONS OF ARNi DE SERPINA1 AND ITS METHODS OF USE AR096390A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361826125P 2013-05-22 2013-05-22

Publications (1)

Publication Number Publication Date
AR096390A1 true AR096390A1 (en) 2015-12-30

Family

ID=56120468

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP140102031A AR096390A1 (en) 2013-05-22 2014-05-22 COMPOSITIONS OF ARNi DE SERPINA1 AND ITS METHODS OF USE

Country Status (1)

Country Link
AR (1) AR096390A1 (en)

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