CL2017000872A1 -
Compositions and methods for the inhibition of the gene expression of hao1 (hydroxy acid oxidase 1 (glycolate oxidase)
- Google Patents
Compositions and methods for the inhibition of the gene expression of hao1 (hydroxy acid oxidase 1 (glycolate oxidase)
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Application filed by Alnylam Pharmaceuticals IncfiledCriticalAlnylam Pharmaceuticals Inc
Publication of CL2017000872A1publicationCriticalpatent/CL2017000872A1/en
<p>LA INVENCIÓN SE REFIERE A AGENTES DE ARNi, POR EJEMPLO, AGENTES DE ARNi BICATENARLOS, QUE SE DIRIGEN AL GEN HAO1 Y MÉTODOS DE USO DE TALES AGENTES DE ARNi PARA INHIBIR LA EXPRESIÓN DE HAO1 Y MÉTODOS DE TRATAMIENTO DE SUJETOS QUE TIENEN, POR EJEMPLO, PH1.</p><p> THE INVENTION REFERS TO ARNi AGENTS, FOR EXAMPLE, ARNi AGENTS BICATENAROS, THAT ARE DIRECTED TO THE HAO1 GENE AND METHODS OF USE OF SUCH ARNI AGENTS TO INHIBIT THE EXPRESSION OF HAO1 AND METHODS OF SUBJECT TREATMENT, FOR EXAMPLE, PH1. </p>
CL2017000872A2014-09-042017-04-10
Compositions and methods for the inhibition of the gene expression of hao1 (hydroxy acid oxidase 1 (glycolate oxidase)
CL2017000872A1
(en)
Compounds derived from 2-oxy-2-phenyl-n-5-pyrrolidin-3-ylamino-1,3,4-thiadiazol-2-ylacetamide, pharmaceutical composition gls1 inhibitors and their use to treat cancer.