AR089309A1 - Metodos de diagnostico en mamiferos que presentan susceptibilidad incrementada a la erosion del esmalte - Google Patents
Metodos de diagnostico en mamiferos que presentan susceptibilidad incrementada a la erosion del esmalteInfo
- Publication number
- AR089309A1 AR089309A1 ARP120104802A ARP120104802A AR089309A1 AR 089309 A1 AR089309 A1 AR 089309A1 AR P120104802 A ARP120104802 A AR P120104802A AR P120104802 A ARP120104802 A AR P120104802A AR 089309 A1 AR089309 A1 AR 089309A1
- Authority
- AR
- Argentina
- Prior art keywords
- level
- enamel
- film
- erosion
- staterin
- Prior art date
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4721—Cationic antimicrobial peptides, e.g. defensins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4725—Mucins, e.g. human intestinal mucin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/988—Lyases (4.), e.g. aldolases, heparinase, enolases, fumarase
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/18—Dental and oral disorders
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Métodos para identificar un mamífero que presenta una susceptibilidad incrementada a la erosión del esmalte. Conjuntos de elementos, usos y otros métodos basados en ellos. Reivindicación 1: Un conjunto de elementos (kit) para identificar pacientes susceptibles a la erosión de la dentina o del esmalte, caracterizado porque comprende (a) un dispositivo para obtener una muestra de la película adquirida del esmalte de la cavidad oral de un mamífero; (b1) una inmunotransferencia para analizar un parámetro de la saliva que se selecciona del grupo que consiste en el nivel de la mucina 5b, el nivel de la anhidrasa carbónica 6, el nivel de la estaterina, el nivel de la estaterina en la película 1 hora después de la adquisición y cualquier combinación de éstos; y/o (b2) un ensayo colorimétrico, un ensayo de espectrometría de masa con plasma de acoplamiento inductivo (ICP/MS) o un ensayo de absorción atómica para analizar el nivel del calcio en la película en la saliva 1 hora después de la adquisición; (c) una solución madre de BCA que comprende (i) ácido bicinconínico, (ii) carbonato de sodio, (iii) bicarbonato de sodio, (iv) tartrato de sodio y (v) pentahidrato de sulfato cúprico de sodio; y (d) instrucciones para identificar los pacientes susceptibles a la erosión de la dentina o del esmalte, donde la susceptibilidad se determina sobre la base de uno o más de los siguientes niveles: (i) un nivel de la mucina 5b inferior a 250 mg/ml, (ii) un nivel de la anhidrasa carbónica 6 inferior a 35 mg/ml, (iii) un nivel de la estaterina superior a 15 mg/ml, (iv) un nivel de la estaterina en la película 1 hora después de la adquisición inferior a 30 ng o (v) un nivel del calcio en la película 1 hora después de la adquisición inferior a 0,001 mol/mm².
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2011/066078 WO2013095367A1 (en) | 2011-12-20 | 2011-12-20 | Diagnostic methods |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR089309A1 true AR089309A1 (es) | 2014-08-13 |
Family
ID=45507887
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP120104802A AR089309A1 (es) | 2011-12-20 | 2012-12-18 | Metodos de diagnostico en mamiferos que presentan susceptibilidad incrementada a la erosion del esmalte |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US9140708B2 (es) |
| EP (1) | EP2795334B1 (es) |
| JP (1) | JP2015507183A (es) |
| CN (1) | CN103998936B (es) |
| AR (1) | AR089309A1 (es) |
| AU (1) | AU2011383728B2 (es) |
| BR (1) | BR112014015040A2 (es) |
| CA (1) | CA2858318A1 (es) |
| MX (1) | MX349984B (es) |
| PH (1) | PH12014501326A1 (es) |
| RU (1) | RU2014129587A (es) |
| SG (1) | SG11201402850YA (es) |
| TW (1) | TWI471564B (es) |
| WO (1) | WO2013095367A1 (es) |
| ZA (1) | ZA201404276B (es) |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7387774B2 (en) * | 1999-11-12 | 2008-06-17 | The Procter & Gamble Co. | Method of enhancing fluoridation and mineralization of teeth |
| US6685920B2 (en) * | 1999-11-12 | 2004-02-03 | The Procter & Gamble Company | Method of protecting teeth against erosion |
| WO2004089187A2 (en) * | 2003-04-01 | 2004-10-21 | University Of Southern California | Caries risk test for predicting and assessing the risk of disease |
| JP2005331341A (ja) * | 2004-05-19 | 2005-12-02 | Horiba Ltd | 口腔内健康維持能力の評価方法および評価装置 |
| JP2007322124A (ja) * | 2004-08-18 | 2007-12-13 | Univ Nihon | う蝕性リスクの判定方法及び判定薬 |
| JP4426500B2 (ja) * | 2005-04-28 | 2010-03-03 | 猛志 奥 | 歯のう蝕罹患リスクの評価方法及び装置並びにプログラム |
| EP2114989B1 (en) | 2007-01-16 | 2016-04-06 | Rutgers, the State University of New Jersey | Natural polypeptides for oral health care |
-
2011
- 2011-12-20 WO PCT/US2011/066078 patent/WO2013095367A1/en active Application Filing
- 2011-12-20 RU RU2014129587A patent/RU2014129587A/ru not_active Application Discontinuation
- 2011-12-20 MX MX2014007556A patent/MX349984B/es active IP Right Grant
- 2011-12-20 EP EP11810948.7A patent/EP2795334B1/en active Active
- 2011-12-20 CN CN201180075691.6A patent/CN103998936B/zh not_active Expired - Fee Related
- 2011-12-20 AU AU2011383728A patent/AU2011383728B2/en not_active Ceased
- 2011-12-20 US US14/366,653 patent/US9140708B2/en active Active
- 2011-12-20 BR BR112014015040A patent/BR112014015040A2/pt not_active IP Right Cessation
- 2011-12-20 JP JP2014548746A patent/JP2015507183A/ja active Pending
- 2011-12-20 CA CA2858318A patent/CA2858318A1/en not_active Abandoned
- 2011-12-20 SG SG11201402850YA patent/SG11201402850YA/en unknown
-
2012
- 2012-12-18 AR ARP120104802A patent/AR089309A1/es unknown
- 2012-12-19 TW TW101148197A patent/TWI471564B/zh not_active IP Right Cessation
-
2014
- 2014-06-10 ZA ZA2014/04276A patent/ZA201404276B/en unknown
- 2014-06-11 PH PH12014501326A patent/PH12014501326A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PH12014501326A1 (en) | 2014-10-20 |
| AU2011383728A1 (en) | 2014-06-19 |
| ZA201404276B (en) | 2016-03-30 |
| CN103998936A (zh) | 2014-08-20 |
| EP2795334A1 (en) | 2014-10-29 |
| US20140348762A1 (en) | 2014-11-27 |
| CN103998936B (zh) | 2016-03-23 |
| RU2014129587A (ru) | 2016-02-20 |
| US9140708B2 (en) | 2015-09-22 |
| MX349984B (es) | 2017-08-23 |
| SG11201402850YA (en) | 2014-10-30 |
| TWI471564B (zh) | 2015-02-01 |
| MX2014007556A (es) | 2014-08-01 |
| TW201331584A (zh) | 2013-08-01 |
| AU2011383728B2 (en) | 2014-09-04 |
| CA2858318A1 (en) | 2013-06-27 |
| WO2013095367A1 (en) | 2013-06-27 |
| EP2795334B1 (en) | 2016-09-28 |
| BR112014015040A2 (pt) | 2017-06-13 |
| JP2015507183A (ja) | 2015-03-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |