AR088721A4 - ANTIMICROBIAL MIXTURE AND APPOSITION WITH ANTIMICROBIAL EFFECT TO PROMOTE WOUND HEALING - Google Patents

ANTIMICROBIAL MIXTURE AND APPOSITION WITH ANTIMICROBIAL EFFECT TO PROMOTE WOUND HEALING

Info

Publication number
AR088721A4
AR088721A4 ARM120100766U ARM120100766U AR088721A4 AR 088721 A4 AR088721 A4 AR 088721A4 AR M120100766 U ARM120100766 U AR M120100766U AR M120100766 U ARM120100766 U AR M120100766U AR 088721 A4 AR088721 A4 AR 088721A4
Authority
AR
Argentina
Prior art keywords
mixture
antimicrobial
fibers
wound healing
contact
Prior art date
Application number
ARM120100766U
Other languages
Spanish (es)
Inventor
Zavadil Michal
Valentova Zuzana
Hekrlova Veronika
Velebny Vladimir
Sobotka Lubos
Duskova Sarka
Original Assignee
Contipro Pharma A S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Contipro Pharma A S filed Critical Contipro Pharma A S
Publication of AR088721A4 publication Critical patent/AR088721A4/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/46—Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4425—Pyridinium derivatives, e.g. pralidoxime, pyridostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/225—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/28—Polysaccharides or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/204—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with nitrogen-containing functional groups, e.g. aminoxides, nitriles, guanidines
    • A61L2300/206—Biguanides, e.g. chlorohexidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/204—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with nitrogen-containing functional groups, e.g. aminoxides, nitriles, guanidines
    • A61L2300/208—Quaternary ammonium compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents

Abstract

Una mezcla para promover la cicatrización de heridas que comprende una sal fisiológicamente aceptable de ácido hialurónico y que además comprende una sustancia antimicrobiana seleccionada del grupo que comprende diclorhidrato de octenidina, cetrimida, cloruro de benzalconio, bromuro de benzalconio, clorhexidina, clorhexidina bigluconato, polihexametileno biguanida, bromuro de carbetopendecinio, bromuro de cetiltrimetilamonio y una mezcla de los mismos en cualquier proporción. También se divulga un apósito para promover la cicatrización de heridas con efecto antimicrobiano, que comprende una capa de contacto (K), que contiene en el lado que estará en contacto con la herida un recubrimiento (P) formado por la mezcla mencionada. Reivindicación 2: La mezcla de acuerdo con la reivindicación 1, caracterizada porque además comprende uno o más polisacáridos seleccionados del grupo que comprende polisacáridos nativos o modificados de hialurona, xantano, esquizofilano, quitosán, glucano, alginato, celulosa, b-1-3-glucano y una mezcla de los mismos. Reivindicación 3: La mezcla de acuerdo con la reivindicación 1 ó 2, caracterizada porque dicha sustancia antimicrobiana es diclorhidrato de octenidina. Reivindicación 4: La mezcla de acuerdo con cualquiera de las reivindicaciones 1 a 3, caracterizada porque comprende una sal fisiológicamente aceptable de ácido hialurónico y diclorhidrato de octenidina a una relación de masas de 500:1. Reivindicación 6: La mezcla de acuerdo con cualquiera de las reivindicaciones precedentes, caracterizada porque además comprende un adyuvante que incrementa el efecto antimicrobiano, por ejemplo un agente quelante tal como EDTA, betaína y 2-fenoxietanol. Reivindicación 12: El apósito de acuerdo con la reivindicación 11, caracterizado porque se encuentra en la forma de una formación de múltiples capas y además comprende una o más capas de absorción (A) y una capa de superficie (R), en donde todas las capas están dispuestas en el siguiente orden en la dirección desde la herida: una capa de contacto (K), que contiene por el lado que estará en contacto con la herida o sobre ambos lados, un recubrimiento (P) constituido por la mezcla de cualquiera de las reivindicaciones 1 a 10; una o más capas de absorción (A) y una capa de superficie (R). Reivindicación 13: El apósito de acuerdo con cualquiera de las reivindicaciones 11 ó 12, caracterizado porque la capa de contacto preferentemente es de una tela de punto o tejida de monofilamentos de poliamida (PAD), opcionalmente de fibras cortadas; de tela no tejida o una membrana porosa, de poliuretano, poliéster, viscosa, de mezclas de dichas fibras o de otros materiales, p. ej. de fibras sintéticas tal como polipropileno. Reivindicación 19: El apósito de acuerdo con cualquiera de las reivindicaciones 12 a 18, caracterizado porque la capa de superficie (R) preferentemente se prepara con una tela no tejida de poliéster que opcionalmente puede ser antimicrobiana por tratamiento por impregnación con una sustancia antimicrobiana adecuada o por medio del contenido de fibras antimicrobianas, obtenidas por ejemplo de bambú, o por medio del contenido de micropartículas de plata.A mixture to promote wound healing comprising a physiologically acceptable salt of hyaluronic acid and which further comprises an antimicrobial substance selected from the group comprising octenidine dihydrochloride, cetrimide, benzalkonium chloride, benzalkonium bromide, chlorhexidine, chlorhexidine bigluconate, polyhexamethylene biguanide , carbetopendecinium bromide, cetyltrimethylammonium bromide and a mixture thereof in any proportion. A dressing is also disclosed to promote wound healing with antimicrobial effect, which comprises a contact layer (K), which contains on the side that a coating (P) formed by the aforementioned mixture will be in contact with the wound. Claim 2: The mixture according to claim 1, characterized in that it further comprises one or more polysaccharides selected from the group comprising native or modified polysaccharides of hyalurone, xanthan, schizophilane, chitosan, glucan, alginate, cellulose, b-1-3- glucan and a mixture thereof. Claim 3: The mixture according to claim 1 or 2, characterized in that said antimicrobial substance is octenidine dihydrochloride. Claim 4: The mixture according to any one of claims 1 to 3, characterized in that it comprises a physiologically acceptable salt of hyaluronic acid and octenidine dihydrochloride at a mass ratio of 500: 1. Claim 6: The mixture according to any of the preceding claims, characterized in that it further comprises an adjuvant that increases the antimicrobial effect, for example a chelating agent such as EDTA, betaine and 2-phenoxyethanol. Claim 12: The dressing according to claim 11, characterized in that it is in the form of a multi-layer formation and further comprises one or more absorption layers (A) and a surface layer (R), wherein all layers are arranged in the following order in the direction from the wound: a contact layer (K), which contains on the side that will be in contact with the wound or on both sides, a coating (P) consisting of the mixture of any of claims 1 to 10; one or more absorption layers (A) and a surface layer (R). Claim 13: The dressing according to any of claims 11 or 12, characterized in that the contact layer is preferably of a knitted or woven fabric of polyamide monofilaments (PAD), optionally of cut fibers; of nonwoven fabric or a porous membrane, of polyurethane, polyester, viscose, of mixtures of said fibers or of other materials, e.g. ex. of synthetic fibers such as polypropylene. Claim 19: The dressing according to any of claims 12 to 18, characterized in that the surface layer (R) is preferably prepared with a non-woven polyester fabric that can optionally be antimicrobial by impregnation treatment with a suitable antimicrobial substance or through the content of antimicrobial fibers, obtained for example from bamboo, or through the content of silver microparticles.

ARM120100766U 2011-03-11 2012-03-09 ANTIMICROBIAL MIXTURE AND APPOSITION WITH ANTIMICROBIAL EFFECT TO PROMOTE WOUND HEALING AR088721A4 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CZ201124045U CZ22394U1 (en) 2011-03-11 2011-03-11 Antimicrobial mixture and cover to support healing of wounds with antimicrobial effect

Publications (1)

Publication Number Publication Date
AR088721A4 true AR088721A4 (en) 2014-07-02

Family

ID=44189522

Family Applications (1)

Application Number Title Priority Date Filing Date
ARM120100766U AR088721A4 (en) 2011-03-11 2012-03-09 ANTIMICROBIAL MIXTURE AND APPOSITION WITH ANTIMICROBIAL EFFECT TO PROMOTE WOUND HEALING

Country Status (12)

Country Link
JP (1) JP3196712U (en)
AR (1) AR088721A4 (en)
AT (1) AT13850U1 (en)
BR (1) BR112013023201A2 (en)
CZ (1) CZ22394U1 (en)
DE (1) DE212012000057U1 (en)
DK (1) DK201300152Y3 (en)
FR (1) FR2972355B3 (en)
HU (1) HU4499U (en)
IT (1) ITMI20120370A1 (en)
RU (1) RU149063U1 (en)
WO (1) WO2012122956A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITBO20120185A1 (en) * 2012-04-06 2013-10-07 Emodial S R L ANTIMICROBIAL MEDICATION, ANTIMICROBIAL COMPOSITION AND ITS USE
CZ28634U1 (en) * 2015-05-05 2015-09-14 Contipro Pharma A.S. Hyaluronan and octenidine dihydrochloride-based dental composition
DE102016007892A1 (en) * 2016-06-21 2017-12-21 Nejmo Harb The reactive and protective plaster
CN109328058A (en) 2016-07-27 2019-02-12 株式会社利他药业 Oral mucosa patch material and its manufacturing method
DE102016009877A1 (en) * 2016-08-08 2018-02-08 Nejmo Harb Reaction protective patch
CN106178069A (en) * 2016-08-30 2016-12-07 苏州美迪斯医疗运动用品股份有限公司 A kind of first aid bleeding-stopping dressing and preparation method thereof
JP6839477B2 (en) * 2017-01-30 2021-03-10 多木化学株式会社 Collagen structure
CZ307615B6 (en) * 2017-06-05 2019-01-16 Contipro A.S. An antimicrobial composition comprising a polysaccharide, a stabilizer and a triiodide, a method for its preparation and use
CZ2018428A3 (en) 2018-08-23 2019-12-04 Contipro As A composition containing an iodide and a derivative of hyaluronic acid with an oxidizing effect, process of preparing it and use
CN110652609A (en) * 2019-07-31 2020-01-07 武汉理工大学 Alginate dressing loaded with silver-zinc micro-battery and preparation method thereof
CN111939306A (en) * 2020-08-21 2020-11-17 江苏诺瓦立医疗用品有限公司 Antibacterial dressing and application thereof
US20210378870A1 (en) * 2020-08-24 2021-12-09 University Of Utah Research Foundation Multi-functional analgesic-releasing wound dressing

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1229075B (en) 1985-04-05 1991-07-17 Fidia Farmaceutici Topical compsn. contg. hyaluronic acid deriv. as vehicle
US5128136A (en) 1990-07-16 1992-07-07 The Oregon Health Sciences University Wound healing kit comprised of gelable collagen
US7691829B2 (en) * 1998-03-24 2010-04-06 Petito George D Composition and method for healing tissues
DE102005017845A1 (en) * 2005-04-18 2006-10-19 Lohmann & Rauscher Gmbh & Co. Kg Autosterile, antiseptic collagen preparations, their use and methods of preparation
ITMI20051569A1 (en) * 2005-08-11 2007-02-12 Biokosmes S R L CICATRIZING COMPOSITION
US20070264226A1 (en) * 2006-05-10 2007-11-15 Karagoezian Hampar L Synergistically enhanced disinfecting solutions
CZ303471B6 (en) * 2007-10-03 2012-10-03 Contipro Biotech S.R.O. Composition containing chitosan-glucan intended for healing wounds and preventing adhesion of bandage to wound
EP2323480A4 (en) * 2008-08-28 2013-02-27 Covidien Lp Antimicrobial foam compositions, articles and methods
CN102170916A (en) * 2008-08-28 2011-08-31 泰科保健集团有限合伙公司 Environmentally activated compositions, articles and methods
DE102009049504A1 (en) * 2009-10-15 2011-04-21 Schülke & Mayr GmbH Wound and mucous membrane antiseptic based on bispyridiniumalkanes

Also Published As

Publication number Publication date
ITMI20120370A1 (en) 2012-09-12
FR2972355A3 (en) 2012-09-14
AT13850U1 (en) 2014-10-15
JP3196712U (en) 2015-04-02
RU149063U1 (en) 2014-12-20
DK201300152U1 (en) 2013-10-25
DE212012000057U1 (en) 2013-09-26
HU4499U (en) 2015-01-28
FR2972355B3 (en) 2013-03-22
BR112013023201A2 (en) 2016-09-20
DK201300152Y3 (en) 2014-02-14
WO2012122956A1 (en) 2012-09-20
CZ22394U1 (en) 2011-06-20

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