AR087032A1 - COMPOSITIONS OF GELATINE CAPSULES AND METHODS TO MANUFACTURE THEM - Google Patents

COMPOSITIONS OF GELATINE CAPSULES AND METHODS TO MANUFACTURE THEM

Info

Publication number
AR087032A1
AR087032A1 ARP120102394A AR087032A1 AR 087032 A1 AR087032 A1 AR 087032A1 AR P120102394 A ARP120102394 A AR P120102394A AR 087032 A1 AR087032 A1 AR 087032A1
Authority
AR
Argentina
Prior art keywords
gelatin
composition
release agent
regions
approximately
Prior art date
Application number
Other languages
Spanish (es)
Original Assignee
Gelita Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gelita Ag filed Critical Gelita Ag
Publication of AR087032A1 publication Critical patent/AR087032A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells

Abstract

Se proporciona una composición de cápsula de gelatina que incluye una o varias primeras regiones distintas que comprenden una gelatina y una o varias segundas regiones distintas que comprenden un agente de liberación rápida no hidrosoluble.Reivindicación 1: Una composición de cápsula de gelatina que comprende un recubrimiento de superficie externa y un núcleo, donde el recubrimiento de superficie externa comprende: a) una o varias primeras regiones distintas que comprenden un componente de gelatina, y, b) una o varias segundas regiones distintas que comprenden un agente de liberación rápida. Reivindicación 8: La composición de la reivindicación 1, en donde el agente de liberación rápida comprende una sal de carbonato no hidrosoluble, una sal de carbonato hidrosoluble y combinaciones de ellas. Reivindicación 15: La composición de la reivindicación 1, en donde el recubrimiento de superficie externa además comprende un plastificante. Reivindicación 30: La composición de la reivindicación 1, en donde el núcleo comprende una formulación sólida y una formulación líquida. Reivindicación 53: La composición de la reivindicación 52, en donde el subrecubrimiento comprende un componente de gelatina, un hidrolizado de gelatina, un material polimérico y combinaciones de ellos. Reivindicación 97: Una composición de gelatina que comprende un recubrimiento de superficie externa y un núcleo, donde el recubrimiento de superficie externa comprende: a) un agente de liberación rápida; b) un componente de gelatina; y c) un hidrolizado de gelatina, en donde la composición comprende una relación de masa del agente de liberación rápida respecto del componente de gelatina que varía entre aproximadamente 1:1 y aproximadamente 1:20, en donde el hidrolizado de gelatina tiene un peso molecular que varía entre aproximadamente 100 Daltones y aproximadamente 2000 Daltones, y en donde la composición comprende una relación de masa del componente de gelatina respecto del hidrolizado de gelatina que varía entre aproximadamente 3:1 y aproximadamente 99:1.A gelatin capsule composition is provided that includes one or several different first regions comprising a gelatin and one or several different second regions comprising a non-water soluble quick release agent. Claim 1: A gelatin capsule composition comprising a coating outer surface and a core, wherein the outer surface coating comprises: a) one or several different first regions comprising a gelatin component, and, b) one or several different second regions comprising a rapid release agent. Claim 8: The composition of claim 1, wherein the quick release agent comprises a non-water soluble carbonate salt, a water soluble carbonate salt and combinations thereof. Claim 15: The composition of claim 1, wherein the outer surface coating further comprises a plasticizer. Claim 30: The composition of claim 1, wherein the core comprises a solid formulation and a liquid formulation. Claim 53: The composition of claim 52, wherein the subcoat comprises a gelatin component, a gelatin hydrolyzate, a polymeric material and combinations thereof. Claim 97: A gelatin composition comprising an outer surface coating and a core, wherein the outer surface coating comprises: a) a rapid release agent; b) a jelly component; and c) a gelatin hydrolyzate, wherein the composition comprises a mass ratio of the rapid-release agent with respect to the gelatin component ranging from about 1: 1 to about 1:20, wherein the gelatin hydrolyzate has a molecular weight that it varies between approximately 100 Daltons and approximately 2000 Daltons, and wherein the composition comprises a mass ratio of the gelatin component to the gelatin hydrolyzate which varies between approximately 3: 1 and approximately 99: 1.

ARP120102394 2011-07-01 2012-07-02 COMPOSITIONS OF GELATINE CAPSULES AND METHODS TO MANUFACTURE THEM AR087032A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161503749P 2011-07-01 2011-07-01

Publications (1)

Publication Number Publication Date
AR087032A1 true AR087032A1 (en) 2014-02-05

Family

ID=47437381

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP120102394 AR087032A1 (en) 2011-07-01 2012-07-02 COMPOSITIONS OF GELATINE CAPSULES AND METHODS TO MANUFACTURE THEM

Country Status (3)

Country Link
AR (1) AR087032A1 (en)
TW (1) TW201311296A (en)
WO (1) WO2013006470A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9113640B2 (en) * 2013-09-12 2015-08-25 Ohio State Innovation Foundation Coated shell eggs and method of making same
JP6887456B2 (en) 2018-07-04 2021-06-16 キャプシュゲル・ベルジウム・エヌ・ヴィ A film-forming composition containing a surfactant or a surfactant and a salt as a whitening agent.
EP3983477B1 (en) 2019-06-12 2022-11-02 Capsugel Belgium NV Film, capsule and film-forming composition comprising water-soluble salt as opacifying agent

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1256393B (en) * 1992-11-17 1995-12-04 Inverni Della Beffa Spa MULTI-LAYER MATERIAL FORMS FOR THE CONTROLLED RELEASE OF ACTIVE INGREDIENTS
US6458383B2 (en) * 1999-08-17 2002-10-01 Lipocine, Inc. Pharmaceutical dosage form for oral administration of hydrophilic drugs, particularly low molecular weight heparin
DE10032456A1 (en) * 2000-07-04 2002-01-31 Lohmann Therapie Syst Lts Rapidly disintegrating dosage form for the release of active substances in the mouth or in the body cavities
US20050058703A1 (en) * 2003-08-01 2005-03-17 Chang Robert C. Gelatin capsules
US7879354B2 (en) * 2004-01-13 2011-02-01 Mcneil-Ppc, Inc. Rapidly disintegrating gelatinous coated tablets
US20080102116A1 (en) * 2004-09-13 2008-05-01 Perrigo Company Quick Dissolve Medicament and Method of Manufacturing
US8691272B2 (en) * 2005-12-30 2014-04-08 Intelgenx Corp. Multilayer tablet
US20100112054A1 (en) * 2008-10-23 2010-05-06 Appian Labs, Llc Tablets and discs with compartments with two or more drugs for release at certain intervals and with specific rates

Also Published As

Publication number Publication date
WO2013006470A1 (en) 2013-01-10
TW201311296A (en) 2013-03-16

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