AR085483A1 - TREATMENT OF ATTENTION DEFICIT DISEASE WITH HYPERACTIVITY, TREATMENT METHOD, PHARMACEUTICAL COMBINATION - Google Patents
TREATMENT OF ATTENTION DEFICIT DISEASE WITH HYPERACTIVITY, TREATMENT METHOD, PHARMACEUTICAL COMBINATIONInfo
- Publication number
- AR085483A1 AR085483A1 ARP120100944A ARP120100944A AR085483A1 AR 085483 A1 AR085483 A1 AR 085483A1 AR P120100944 A ARP120100944 A AR P120100944A AR P120100944 A ARP120100944 A AR P120100944A AR 085483 A1 AR085483 A1 AR 085483A1
- Authority
- AR
- Argentina
- Prior art keywords
- treatment
- hyperactivity
- azabicyclo
- benzofuran
- pyridinyl
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Reivindicación 1: Un método de tratamiento de TDAH, caracterizado porque comprende administrar una cantidad terapéuticamente eficaz de (2S,3R)-N-(2-((3-piridinil)metil)-1-azabiciclo[2.2.2]oct-3-il)benzofuran-2-carboxamida o una sal farmacéuticamente aceptable de ella.Reivindicación 16: Una combinación de (2S,3R)-N-(2-((3-piridinil)metil)-1-azabiciclo[2.2.2]oct-3-il)benzofuran-2-carboxamida o una sal farmacéuticamente aceptable de ella, u otro agonista de a7, con uno o más agentes estimulantes, uno o más agentes antidepresivos y uno o más agentes antihipertensivos para tratar el TDAH del tipo combinado, desatento o hiperactivo/impulsivo. Reivindicación 17: Una combinación de (2S,3R)-N-(2-((3-piridinil)metil)-1-azabiciclo[2.2.2loct-3-il)benzofuran-2-carboxamida o una sal farmacéuticamente aceptable de ella con otro agente terapéutico para tratar el TDAH.Claim 1: An ADHD treatment method, characterized in that it comprises administering a therapeutically effective amount of (2S, 3R) -N- (2 - ((3-pyridinyl) methyl) -1-azabicyclo [2.2.2] oct-3 -yl) benzofuran-2-carboxamide or a pharmaceutically acceptable salt thereof. Claim 16: A combination of (2S, 3R) -N- (2 - ((3-pyridinyl) methyl) -1-azabicyclo [2.2.2] oct-3-yl) benzofuran-2-carboxamide or a pharmaceutically acceptable salt thereof, or other a7 agonist, with one or more stimulating agents, one or more antidepressant agents and one or more antihypertensive agents for treating ADHD of the combined type , inattentive or hyperactive / impulsive. Claim 17: A combination of (2S, 3R) -N- (2 - ((3-pyridinyl) methyl) -1-azabicyclo [2.2.2loct-3-yl) benzofuran-2-carboxamide or a pharmaceutically acceptable salt thereof with another therapeutic agent to treat ADHD.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161466644P | 2011-03-23 | 2011-03-23 | |
US201161489740P | 2011-05-25 | 2011-05-25 | |
US201161510092P | 2011-07-21 | 2011-07-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR085483A1 true AR085483A1 (en) | 2013-10-02 |
Family
ID=45922840
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP120100944A AR085483A1 (en) | 2011-03-23 | 2012-03-22 | TREATMENT OF ATTENTION DEFICIT DISEASE WITH HYPERACTIVITY, TREATMENT METHOD, PHARMACEUTICAL COMBINATION |
Country Status (3)
Country | Link |
---|---|
AR (1) | AR085483A1 (en) |
TW (1) | TW201244717A (en) |
WO (1) | WO2012129262A1 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103896826B (en) * | 2012-12-26 | 2016-08-03 | 上海朴颐化学科技有限公司 | The method of asymmetric synthesis of (3R, 4R)-3-methylamino-4-methyl piperidine of nitrogen protection, relevant intermediate and method for preparing raw material |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4922901A (en) | 1988-09-08 | 1990-05-08 | R. J. Reynolds Tobacco Company | Drug delivery articles utilizing electrical energy |
IL107184A (en) | 1992-10-09 | 1997-08-14 | Abbott Lab | Heterocyclic ether compounds that enhance cognitive function |
US5852041A (en) | 1993-04-07 | 1998-12-22 | Sibia Neurosciences, Inc. | Substituted pyridines useful as modulators of acethylcholine receptors |
US5604231A (en) | 1995-01-06 | 1997-02-18 | Smith; Carr J. | Pharmaceutical compositions for prevention and treatment of ulcerative colitis |
US5597919A (en) | 1995-01-06 | 1997-01-28 | Dull; Gary M. | Pyrimidinyl or Pyridinyl alkenyl amine compounds |
US5585388A (en) | 1995-04-07 | 1996-12-17 | Sibia Neurosciences, Inc. | Substituted pyridines useful as modulators of acetylcholine receptors |
US5583140A (en) | 1995-05-17 | 1996-12-10 | Bencherif; Merouane | Pharmaceutical compositions for the treatment of central nervous system disorders |
IL118279A (en) | 1995-06-07 | 2006-10-05 | Abbott Lab | 3 - pyridyloxy (or thio) alkyl heterocyclic compounds, pharmaceutical compositions containing them and their uses in the preparation of medicaments for controlling chemical synaptic transmission |
US5616716A (en) | 1996-01-06 | 1997-04-01 | Dull; Gary M. | (3-(5-ethoxypyridin)yl)-alkenyl 1 amine compounds |
US5663356A (en) | 1996-04-23 | 1997-09-02 | Ruecroft; Graham | Method for preparation of aryl substituted alefinic secondary amino compounds |
US6953855B2 (en) | 1998-12-11 | 2005-10-11 | Targacept, Inc. | 3-substituted-2(arylalkyl)-1-azabicycloalkanes and methods of use thereof |
SA08290475B1 (en) | 2007-08-02 | 2013-06-22 | Targacept Inc | (2S,3R)-N-(2-((3-Pyridinyl)Methyl)-1-Azabicyclo[2.2.2]Oct-3-yl)Benzofuran-2-Carboxamide, Novel Salt forms, and Methods of Use Thereof |
-
2012
- 2012-03-21 WO PCT/US2012/029879 patent/WO2012129262A1/en active Application Filing
- 2012-03-22 TW TW101109949A patent/TW201244717A/en unknown
- 2012-03-22 AR ARP120100944A patent/AR085483A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2012129262A1 (en) | 2012-09-27 |
TW201244717A (en) | 2012-11-16 |
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Legal Events
Date | Code | Title | Description |
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FA | Abandonment or withdrawal |