AR082843A1 - Procedimiento para la preparacion de diacido 3,6,9-triaza-3,6,9-tris(carboximetil)-4-(4-etoxibencil)-undecanoico cristalino y el uso para la preparacion de primovist - Google Patents

Procedimiento para la preparacion de diacido 3,6,9-triaza-3,6,9-tris(carboximetil)-4-(4-etoxibencil)-undecanoico cristalino y el uso para la preparacion de primovist

Info

Publication number
AR082843A1
AR082843A1 ARP110102017A AR082843A1 AR 082843 A1 AR082843 A1 AR 082843A1 AR P110102017 A ARP110102017 A AR P110102017A AR 082843 A1 AR082843 A1 AR 082843A1
Authority
AR
Argentina
Prior art keywords
preparation
triaza
tris
etoxibencil
condecanoico
Prior art date
Application number
Other languages
English (en)
Inventor
Wilhelm Trentmann
Johannes Platzek
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Publication of AR082843A1 publication Critical patent/AR082843A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/38—Separation; Purification; Stabilisation; Use of additives
    • C07C227/40—Separation; Purification
    • C07C227/42—Crystallisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • C07C229/16—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of hydrocarbon radicals substituted by amino or carboxyl groups, e.g. ethylenediamine-tetra-acetic acid, iminodiacetic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Reivindicación 1: Procedimiento para la preparación de diácido 3,6,9-triaza-3,6,9-tris(carboximetil)-4-(4-etoxibencil)-undecanoico cristalino de la fórmula (1) caracterizado porque se hidroliza éster di-ter-butílico del diácido 3,6,9-triaza-3,6,9-tris-(terc.butoxi-carbonilmetil)-4-(4-etoxibencil)-undecanoico de la fórmula (2) con una solución acuosa de hidróxido de metal alcalino, se concentra, el residuo se disuelve en agua y la solución obtenida se acidifica y se filtra del precipitado.
ARP110102017 2010-06-11 2011-06-10 Procedimiento para la preparacion de diacido 3,6,9-triaza-3,6,9-tris(carboximetil)-4-(4-etoxibencil)-undecanoico cristalino y el uso para la preparacion de primovist AR082843A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE201010023890 DE102010023890A1 (de) 2010-06-11 2010-06-11 Verfahren zur Herstellung kristalliner 3,6,9-Triaza-3,6,9-tris(carboxymethyl)-4-(ethoxybenzyl)-undecandinsäure und die Verwendung zur Herstellung von Primovist

Publications (1)

Publication Number Publication Date
AR082843A1 true AR082843A1 (es) 2013-01-16

Family

ID=44512793

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP110102017 AR082843A1 (es) 2010-06-11 2011-06-10 Procedimiento para la preparacion de diacido 3,6,9-triaza-3,6,9-tris(carboximetil)-4-(4-etoxibencil)-undecanoico cristalino y el uso para la preparacion de primovist

Country Status (3)

Country Link
AR (1) AR082843A1 (es)
BR (1) BR112012031577A2 (es)
DE (1) DE102010023890A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104761461A (zh) * 2014-09-09 2015-07-08 山东富创医药科技有限公司 一种新的钆塞酸二钠中间体的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3640708C2 (de) 1986-11-28 1995-05-18 Schering Ag Verbesserte metallhaltige Pharmazeutika
DE3922005A1 (de) 1989-06-30 1991-01-10 Schering Ag Derivatisierte dtpa-komplexe, diese verbindungen enthaltende pharmazeutische mittel, ihre verwendung und verfahren zu deren herstellung

Also Published As

Publication number Publication date
BR112012031577A2 (pt) 2016-11-08
DE102010023890A1 (de) 2011-12-15

Similar Documents

Publication Publication Date Title
AR117799A2 (es) Sal(es) de dimetil-amida del ácido 7-ciclopentil-2-(5-piperazin-1-il-piridin-2-il-amino)-7h-pirrolo-[2,3-d]-pirimidin-6-carboxílico y procesos para su elaboración
ES2660773T3 (es) Procedimiento para la preparación de una sal cristalina trialcalino-metálica de L-MGDA
CU20120168A7 (es) Procedimiento para la preparación de diácido 3,6,9-tris(carboximetil)-4-(etoxibencil)-undecanoico cristalino y el uso para la preparación de primovist®
AR084535A1 (es) Procedimiento para la preparacion de una solucion de dioxido de cloro estable acuosa
RU2013120972A (ru) Гидроксид магния с высоким соотношением размеров кристаллов
MX2015014565A (es) Jabon liquido que tiene actividad antibacteriana mejorada.
CL2008001549A1 (es) Complejo de hierro soluble en agua con maltodextrinas derivatizadas y oxidadas en c1; procedimiento para su preparacion; composicion farmaceutica; y su uso para el tratamiento o profilaxis de anemias de deficiencia de hierro.
EP3066926A3 (en) Aqueous herbicidal concentrates of auxinic carboxylic acids with reduced eye irritancy
WO2013116753A8 (en) Fatty acids as anti-inflammatory agents
PE20141365A1 (es) Proceso para la preparacion de una solucion acuosa que comprende al menos un carbonato acido alcalinoterreo y su uso
RU2009101326A (ru) Препарат для наружного применения на кожу, содержащий тритерпеновую кислоту
CL2008002341A1 (es) Proceso para la produccion de escorodita cristalina a partir de una solucion acuosa acida que contiene as pentavalente y fe trivalente en donde la sintesis de la escorodita se lleva a cabo despues que la tasa molar de fe a as contenido en la solucion es ajustada para que sea entre 0,9 y 1,1; y proceso para el reciclo de una solucion.
DK2022332T3 (da) Vandigt desinfektionsmiddel til nedsættelse af kimtallet i luft
MX2015001019A (es) Preparacion para tratamiento de heridas y llagas que comprende hipoclorito y aminoacidos.
AR082843A1 (es) Procedimiento para la preparacion de diacido 3,6,9-triaza-3,6,9-tris(carboximetil)-4-(4-etoxibencil)-undecanoico cristalino y el uso para la preparacion de primovist
EP2499915A4 (en) VIRAL INACTIVATION AGENT
AR042491A1 (es) Formula nutricional acidificada
MX2012003733A (es) Composiciones de dibromomalonamida y su uso como biocidas.
UY33442A (es) Procedimiento para la preparación de diácido 3,6,9-triaza-3,6,9-tris(carboximetil)-4-(4-etoxibencil)-undecanoico cristalino y el uso para la preparación de primovisto
RU2011146227A (ru) Способ получения хитозан-нуклеинового гидролизата
ES2542777T3 (es) Bebida
IN2015DN03114A (es)
CN105296218A (zh) 一种杀菌洁厕剂
DOP2012000309A (es) Procedimiento para la preparacion de diacido 3,6,9-triaza-3,6,9-tris(carboximetil)-4-(4-etoxibencil)-undecanoico cristalino y el uso para la preparacion del complejo de gadolinio del diacido 3,6,9-triaza-3,6,9-tris(carboximetil)-4-(4-etoxibencil)-undecanoico"
CN203634521U (zh) 一种可监测消毒水量的消毒架

Legal Events

Date Code Title Description
FB Suspension of granting procedure