AR075208A1 - DERIVATIVES OF 4-AMINO-7,8-DIHIDROPIRIDO [4,3-D] PIRIMIDIN-5 (6H) -ONA, PHARMACEUTICAL COMPOSITIONS THAT UNDERSTAND AND USE THE SAME IN THE TREATMENT OF OBESITY AND / OR DIABETES. - Google Patents
DERIVATIVES OF 4-AMINO-7,8-DIHIDROPIRIDO [4,3-D] PIRIMIDIN-5 (6H) -ONA, PHARMACEUTICAL COMPOSITIONS THAT UNDERSTAND AND USE THE SAME IN THE TREATMENT OF OBESITY AND / OR DIABETES.Info
- Publication number
- AR075208A1 AR075208A1 ARP100100265A ARP100100265A AR075208A1 AR 075208 A1 AR075208 A1 AR 075208A1 AR P100100265 A ARP100100265 A AR P100100265A AR P100100265 A ARP100100265 A AR P100100265A AR 075208 A1 AR075208 A1 AR 075208A1
- Authority
- AR
- Argentina
- Prior art keywords
- dihidropirido
- pirimidin
- ona
- obesity
- diabetes
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Reivindicacion 1: Un compuesto que tiene la formula (1) en la que R1 es H, alcoxi C1-2, alquilo C1-2 halosustituido, alcoxi C1-2 halosustituido o alquilo C1-2; cada R2 es independientemente halogeno, OH, alquilo C1-4, ciano, cicloalquilo C3-6 o alcoxi C1-4; R3 es H, alquilo C1-2, alcoxi C1-2, o -O-alquilo C1-2-alcoxi C1-2; y m es 0, 1, 2, o 3; o una sal farmacéuticamente aceptable del mismo.Claim 1: A compound having the formula (1) wherein R1 is H, C1-2 alkoxy, halosubstituted C1-2 alkyl, halosubstituted C1-2 alkoxy or C1-2 alkyl; each R2 is independently halogen, OH, C1-4 alkyl, cyano, C3-6 cycloalkyl or C1-4 alkoxy; R3 is H, C1-2 alkyl, C1-2 alkoxy, or -O-C1-2 alkyl-C1-2 alkoxy; and m is 0, 1, 2, or 3; or a pharmaceutically acceptable salt thereof.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14952209P | 2009-02-03 | 2009-02-03 | |
| US28525809P | 2009-12-10 | 2009-12-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR075208A1 true AR075208A1 (en) | 2011-03-16 |
Family
ID=42060744
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP100100265A AR075208A1 (en) | 2009-02-03 | 2010-02-01 | DERIVATIVES OF 4-AMINO-7,8-DIHIDROPIRIDO [4,3-D] PIRIMIDIN-5 (6H) -ONA, PHARMACEUTICAL COMPOSITIONS THAT UNDERSTAND AND USE THE SAME IN THE TREATMENT OF OBESITY AND / OR DIABETES. |
Country Status (4)
| Country | Link |
|---|---|
| AR (1) | AR075208A1 (en) |
| TW (1) | TW201040174A (en) |
| UY (1) | UY32412A (en) |
| WO (1) | WO2010089685A1 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6099753B2 (en) * | 2012-10-03 | 2017-03-22 | アドビナス セラピューティクス リミテッド | Spirocyclic compound, composition thereof and pharmaceutical application thereof |
| CN111018833B (en) * | 2019-12-13 | 2021-01-01 | 宁波申泰生物科技有限公司 | Apixaban intermediate and preparation method thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6100077A (en) | 1998-10-01 | 2000-08-08 | The Trustees Of Columbia University In The City Of New York | Isolation of a gene encoding diacylglycerol acyltransferase |
| EP1383501B1 (en) | 2001-02-28 | 2007-04-04 | Merck & Co., Inc. | Acylated piperidine derivatives as melanocortin-4 receptor agonists |
| EP1562956A4 (en) | 2002-11-22 | 2007-10-10 | Japan Tobacco Inc | Fused bicyclic nitrogen-containing heterocycles |
| WO2005017187A2 (en) | 2003-08-04 | 2005-02-24 | Bayer Pharmaceuticals Corporation | Methods for screening and identifying compounds |
| AU2005209115A1 (en) * | 2004-01-30 | 2005-08-11 | Japan Tobacco Inc. | Anorectic compounds |
| AP2006003768A0 (en) | 2004-05-25 | 2006-10-31 | Pfizer Prod Inc | TetraazabenzoÄeÜazulene derivatives and analogs tehereof |
| PA8660701A1 (en) | 2005-02-04 | 2006-09-22 | Pfizer Prod Inc | SMALL AGONISTS AND THEIR USES |
| US20090036425A1 (en) * | 2007-08-02 | 2009-02-05 | Pfizer Inc | Substituted bicyclolactam compounds |
-
2010
- 2010-01-28 WO PCT/IB2010/050395 patent/WO2010089685A1/en active Application Filing
- 2010-01-28 TW TW099102431A patent/TW201040174A/en unknown
- 2010-02-01 AR ARP100100265A patent/AR075208A1/en not_active Application Discontinuation
- 2010-02-02 UY UY0001032412A patent/UY32412A/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2010089685A1 (en) | 2010-08-12 |
| UY32412A (en) | 2010-09-30 |
| TW201040174A (en) | 2010-11-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |