AR075029A1 - METHOD TO PRODUCE A PROTEIN OR A PHYSIOLOGICALLY ACTIVE PEPTIDE USING AN IMMUNOGLOBULIN FRAGMENT - Google Patents

METHOD TO PRODUCE A PROTEIN OR A PHYSIOLOGICALLY ACTIVE PEPTIDE USING AN IMMUNOGLOBULIN FRAGMENT

Info

Publication number
AR075029A1
AR075029A1 ARP100100113A AR075029A1 AR 075029 A1 AR075029 A1 AR 075029A1 AR P100100113 A ARP100100113 A AR P100100113A AR 075029 A1 AR075029 A1 AR 075029A1
Authority
AR
Argentina
Prior art keywords
protein
physiologically active
produce
immunoglobulin fragment
active peptide
Prior art date
Application number
Other languages
Spanish (es)
Inventor
Byung Sun Lee
Se Chang Kwon
Gwan Sun Lee
Sung Youb Jung
Jin-Sun Kim
Jong-Soo Lee
Original Assignee
Hanmi Pharm Ind Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hanmi Pharm Ind Co Ltd filed Critical Hanmi Pharm Ind Co Ltd
Publication of AR075029A1 publication Critical patent/AR075029A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Método para producir en masa una proteína o un péptido fisiologicamente activo usando una proteína de fusion compuesta de la proteína o del péptido fisiologicamente activo y un fragmento de inmunoglobulina. También se provee dicha proteína de fusion, un ADN que codifica la proteína de fusion, un vector de expresion que comprende el ADN, y un microorganismo transformado con el vector de expresion.Method for mass producing a physiologically active protein or peptide using a fusion protein composed of the physiologically active protein or peptide and an immunoglobulin fragment. Said fusion protein is also provided, a DNA encoding the fusion protein, an expression vector comprising the DNA, and a microorganism transformed with the expression vector.

ARP100100113 2009-01-19 2010-01-19 METHOD TO PRODUCE A PROTEIN OR A PHYSIOLOGICALLY ACTIVE PEPTIDE USING AN IMMUNOGLOBULIN FRAGMENT AR075029A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR20090004234 2009-01-19

Publications (1)

Publication Number Publication Date
AR075029A1 true AR075029A1 (en) 2011-03-02

Family

ID=42340231

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP100100113 AR075029A1 (en) 2009-01-19 2010-01-19 METHOD TO PRODUCE A PROTEIN OR A PHYSIOLOGICALLY ACTIVE PEPTIDE USING AN IMMUNOGLOBULIN FRAGMENT

Country Status (4)

Country Link
KR (1) KR20100084996A (en)
AR (1) AR075029A1 (en)
TW (1) TW201031752A (en)
WO (1) WO2010082804A2 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3404102T3 (en) 2004-04-21 2021-12-13 Alexion Pharmaceuticals, Inc. Bone delivery conjugates and method of using same to target proteins to bone
CA2823066A1 (en) 2010-12-27 2012-07-05 Alexion Pharma International Sarl Compositions comprising natriuretic peptides and methods of use thereof
US10052366B2 (en) 2012-05-21 2018-08-21 Alexion Pharmaceuticsl, Inc. Compositions comprising alkaline phosphatase and/or natriuretic peptide and methods of use thereof
US10822596B2 (en) 2014-07-11 2020-11-03 Alexion Pharmaceuticals, Inc. Compositions and methods for treating craniosynostosis
RU2708068C2 (en) 2014-12-05 2019-12-04 Алексион Фармасьютикалз, Инк. Treating convulsions using recombinant alkaline phosphatase
JP6868561B2 (en) 2015-01-28 2021-05-12 アレクシオン ファーマシューティカルズ， インコーポレイテッド How to treat subjects with alkaline phosphatase deficiency
CN108350440A (en) 2015-08-17 2018-07-31 阿雷克森制药公司 The manufacture of alkaline phosphate ester
EP3355904A4 (en) 2015-09-28 2019-06-12 Alexion Pharmaceuticals, Inc. Identifying effective dosage regimens for tissue non-specific alkaline phosphatase (tnsalp)-enzyme replacement therapy of hypophosphatasia
WO2017074466A1 (en) 2015-10-30 2017-05-04 Alexion Pharmaceuticals, Inc. Methods for treating craniosynostosis in a patient
US11065306B2 (en) 2016-03-08 2021-07-20 Alexion Pharmaceuticals, Inc. Methods for treating hypophosphatasia in children
EP3436052A4 (en) 2016-04-01 2019-10-09 Alexion Pharmaceuticals, Inc. Treating muscle weakness with alkaline phosphatases
US10898549B2 (en) 2016-04-01 2021-01-26 Alexion Pharmaceuticals, Inc. Methods for treating hypophosphatasia in adolescents and adults
WO2017214130A1 (en) 2016-06-06 2017-12-14 Alexion Pharmaceuticals, Inc. Metal impact on manufacturing of alkaline phosphatases
JP7018933B2 (en) 2016-08-18 2022-02-14 アレクシオン ファーマシューティカルズ， インコーポレイテッド How to treat bronchomalacia
US11224637B2 (en) 2017-03-31 2022-01-18 Alexion Pharmaceuticals, Inc. Methods for treating hypophosphatasia (HPP) in adults and adolescents
WO2019190752A1 (en) 2018-03-30 2019-10-03 Alexion Pharmaceuticals, Inc. Manufacturing of glycoproteins
WO2020060202A1 (en) * 2018-09-18 2020-03-26 한국생산기술연구원 Expression cassette for preparing thymulin or argireline, and use thereof
KR102124035B1 (en) * 2018-09-18 2020-06-19 한국생산기술연구원 A expression cassette for preparation of thymulin and use thereof
CN111208243B (en) * 2018-11-21 2022-05-17 中国科学院大连化学物理研究所 Anion exchange chromatographic column-based SUMO peptide fragment enrichment method

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5196321A (en) * 1986-10-02 1993-03-23 Massachusetts Institute Of Technology Methods for in vitro cleavage of ubiquitin fusion proteins
US5225538A (en) * 1989-02-23 1993-07-06 Genentech, Inc. Lymphocyte homing receptor/immunoglobulin fusion proteins
US5349053A (en) * 1990-06-01 1994-09-20 Protein Design Labs, Inc. Chimeric ligand/immunoglobulin molecules and their uses
US6900292B2 (en) * 2001-08-17 2005-05-31 Lee-Hwei K. Sun Fc fusion proteins of human erythropoietin with increased biological activities
EP1682584B1 (en) * 2003-11-13 2013-04-17 Hanmi Science Co., Ltd. A pharmaceutical composition comprising an immunoglobulin fc region as a carrier

Also Published As

Publication number Publication date
WO2010082804A2 (en) 2010-07-22
TW201031752A (en) 2010-09-01
KR20100084996A (en) 2010-07-28
WO2010082804A3 (en) 2010-11-25

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