AR070530A1 - COMPRESSED ORAL DISINTEGRATION - Google Patents
COMPRESSED ORAL DISINTEGRATIONInfo
- Publication number
- AR070530A1 AR070530A1 ARP090100682A ARP090100682A AR070530A1 AR 070530 A1 AR070530 A1 AR 070530A1 AR P090100682 A ARP090100682 A AR P090100682A AR P090100682 A ARP090100682 A AR P090100682A AR 070530 A1 AR070530 A1 AR 070530A1
- Authority
- AR
- Argentina
- Prior art keywords
- disintegrating tablet
- classes
- oral disintegrating
- group
- tablet according
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Zoology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invencion se refiere a un comprimido desintegrante oral que comprende cilostazol, manitol, sacárido distinto de manitol, sustancia inorgánica, y agente desintegrante, así como excipiente orgánico y deslizante, que es posible tomar con manipulacion sencilla por muchos pacientes a los cuales se aplican los comprimidos de cilostazol, especialmente pacientes de edad avanzada y pacientes que sufren de disfagia. Reivindicacion 4: El comprimido desintegrante oral de acuerdo con la reivindicacion 3, caracterizado porque el deslizante es una o más clases de deslizantes seleccionadas del grupo que consiste de dioxido de silicio hidratado, ácido silícico anhidro liviano, y ácido silícico anhidro pesado. Reivindicacion 7: El comprimido desintegrante oral de acuerdo con la reivindicacion 6, caracterizado porque el excipiente orgánico es una o más clases de excipientes seleccionadas del grupo que consiste de almidones y celulosa. Reivindicacion 13: El comprimido desintegrante oral de acuerdo con cualquiera de las reivindicaciones 1 a 12 caracterizado porque opcionalmente también puede comprender una o más clases de aditivos seleccionado del grupo que consiste de lubricantes, edulcorantes, sustancias saborizantes, aromatizantes, aglutinantes y colorantes.The present invention relates to an oral disintegrating tablet comprising cilostazol, mannitol, saccharide other than mannitol, inorganic substance, and disintegrating agent, as well as organic and sliding excipient, which can be taken with simple manipulation by many patients to whom they are applied. Cilostazol tablets, especially elderly patients and patients suffering from dysphagia. Claim 4: The oral disintegrating tablet according to claim 3, characterized in that the slider is one or more classes of sliders selected from the group consisting of hydrated silicon dioxide, light anhydrous silicic acid, and heavy anhydrous silicic acid. Claim 7: The oral disintegrating tablet according to claim 6, characterized in that the organic excipient is one or more classes of excipients selected from the group consisting of starches and cellulose. Claim 13: The oral disintegrating tablet according to any one of claims 1 to 12 characterized in that it may optionally also comprise one or more classes of additives selected from the group consisting of lubricants, sweeteners, flavoring substances, flavorings, binders and colorants.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2008050460 | 2008-02-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR070530A1 true AR070530A1 (en) | 2010-04-14 |
Family
ID=40718911
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP090100682A AR070530A1 (en) | 2008-02-29 | 2009-02-27 | COMPRESSED ORAL DISINTEGRATION |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP2262487A2 (en) |
JP (1) | JP2011513194A (en) |
AR (1) | AR070530A1 (en) |
CL (1) | CL2009000452A1 (en) |
PE (1) | PE20091560A1 (en) |
TW (1) | TW200936184A (en) |
WO (1) | WO2009107864A2 (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011158110A2 (en) | 2010-04-28 | 2011-12-22 | Nuformix Limited | Cilostazol cocrystals and compositions |
ES2422657B1 (en) * | 2012-02-10 | 2014-06-11 | Laboratorios Normon S.A. | Cilostazol solid pharmaceutical composition |
CN104487094B (en) | 2012-07-20 | 2017-05-17 | 大塚制药株式会社 | Tablet having dry-ink film on surface thereof, and ink for inkjet printer |
JP5713421B1 (en) | 2013-07-19 | 2015-05-07 | 株式会社三和化学研究所 | Orally disintegrating tablets |
US9974738B2 (en) | 2013-09-27 | 2018-05-22 | Daicel Corporation | Disintegrating particle composition produced by two-stage wet granulation process, and intraorally disintegrating tablet containing same composition |
US10231914B2 (en) * | 2015-06-02 | 2019-03-19 | Lynette Batton | Effervescent tablet for elimination of red wine discoloration, offensive odour of mouth and cleaning the palate |
EP3409294A1 (en) | 2017-06-01 | 2018-12-05 | Przedsiebiorstwo Farmaceutyczne Lek-Am Sp Z O. O. | Tablets containing cilostazol of specific particle size distribution |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6548490B1 (en) * | 1997-10-28 | 2003-04-15 | Vivus, Inc. | Transmucosal administration of phosphodiesterase inhibitors for the treatment of erectile dysfunction |
WO2001076565A1 (en) * | 2000-04-12 | 2001-10-18 | Banyu Pharmaceutical Co., Ltd. | Compositions disintegrating in oral cavity and preparations disintegrating in oral cavity |
JP4637338B2 (en) * | 2000-09-22 | 2011-02-23 | 大塚製薬株式会社 | Cilostazol dry coated tablets |
JP4551627B2 (en) * | 2003-02-28 | 2010-09-29 | 東和薬品株式会社 | Method for producing orally disintegrating tablets |
IN234086B (en) * | 2003-10-15 | 2009-05-29 | Fuji Chem Ind Co Ltd | |
JP3841804B2 (en) * | 2003-10-15 | 2006-11-08 | 富士化学工業株式会社 | Composition for intraorally rapidly disintegrating tablets |
TWI383809B (en) * | 2005-06-29 | 2013-02-01 | Otsuka Pharma Co Ltd | Orally disintegrating powder comprising cilostazol |
WO2007029376A1 (en) * | 2005-09-02 | 2007-03-15 | Fuji Chemical Industry Co., Ltd. | Orally rapidly disintegrating tablet |
-
2009
- 2009-02-26 JP JP2010504975A patent/JP2011513194A/en active Pending
- 2009-02-26 EP EP09714454A patent/EP2262487A2/en not_active Withdrawn
- 2009-02-26 WO PCT/JP2009/054115 patent/WO2009107864A2/en active Application Filing
- 2009-02-27 CL CL2009000452A patent/CL2009000452A1/en unknown
- 2009-02-27 TW TW098106341A patent/TW200936184A/en unknown
- 2009-02-27 AR ARP090100682A patent/AR070530A1/en unknown
- 2009-02-27 PE PE2009000311A patent/PE20091560A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
PE20091560A1 (en) | 2009-10-30 |
JP2011513194A (en) | 2011-04-28 |
WO2009107864A3 (en) | 2009-12-03 |
WO2009107864A2 (en) | 2009-09-03 |
EP2262487A2 (en) | 2010-12-22 |
TW200936184A (en) | 2009-09-01 |
CL2009000452A1 (en) | 2010-03-26 |
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