AR067909A1 - Peptidos modificados que tienen efectos mejoradores de toxinas - Google Patents
Peptidos modificados que tienen efectos mejoradores de toxinasInfo
- Publication number
- AR067909A1 AR067909A1 ARP080103504A AR067909A1 AR 067909 A1 AR067909 A1 AR 067909A1 AR P080103504 A ARP080103504 A AR P080103504A AR 067909 A1 AR067909 A1 AR 067909A1
- Authority
- AR
- Argentina
- Prior art keywords
- btb
- toxin
- potentiation
- insect
- increased
- Prior art date
Links
- 239000003053 toxin Substances 0.000 title abstract 4
- 231100000765 toxin Toxicity 0.000 title abstract 4
- 108091005601 modified peptides Proteins 0.000 title 1
- 241000238631 Hexapoda Species 0.000 abstract 5
- 108091005804 Peptidases Proteins 0.000 abstract 3
- 108700012359 toxins Proteins 0.000 abstract 3
- 102000000905 Cadherin Human genes 0.000 abstract 2
- 108050007957 Cadherin Proteins 0.000 abstract 2
- 102000035195 Peptidases Human genes 0.000 abstract 2
- 239000012634 fragment Substances 0.000 abstract 2
- 235000019833 protease Nutrition 0.000 abstract 2
- 241000566547 Agrotis ipsilon Species 0.000 abstract 1
- 241000255967 Helicoverpa zea Species 0.000 abstract 1
- 239000004365 Protease Substances 0.000 abstract 1
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 abstract 1
- 241000256247 Spodoptera exigua Species 0.000 abstract 1
- 238000003776 cleavage reaction Methods 0.000 abstract 1
- 239000013078 crystal Substances 0.000 abstract 1
- 230000001079 digestive effect Effects 0.000 abstract 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 abstract 1
- 210000000936 intestine Anatomy 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 235000019419 proteases Nutrition 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000007017 scission Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
- A01N37/46—N-acyl derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
- C07K14/325—Bacillus thuringiensis crystal peptides, i.e. delta-endotoxins
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Agronomy & Crop Science (AREA)
- Engineering & Computer Science (AREA)
- Insects & Arthropods (AREA)
- Crystallography & Structural Chemistry (AREA)
- Toxicology (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Environmental Sciences (AREA)
- Peptides Or Proteins (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
La presente se relaciona, en parte, con la modificacion de péptidos BtBooster (BtB), en parte para incrementar su estabilidad en los jugos digestivos del intestino medio del insecto. En algunas realizaciones preferidas de BtB se han suprimido los sitios de escision de proteinasa dando lugar a estabilidad incrementada de la BtB modificada en el intestino del insecto, reteniendo al mismo tiempo la capacidad para potenciar las proteínas de B.t. para un control de insectos mejorado. En algunas realizaciones preferidas, se utiliza la BtB estable en proteasa en combinacion con esporas y/o cristales que comprenden una proteína Cry. También se da a conocer en la presente la potenciacion incrementada de las toxinas Bt contra insectos relativamente tolerantes a Bt (Helicoverpa zea, Spodoptera exigua y Agrotis ipsilon), cuando se las utiliza con BtBs. También describimos la potenciacion incrementada de lasa toxinas con fragmentos de cadherina que están estabilizados contra la sobredigestion por las proteinasas del intestino medio de los insectos. Damos a conocer asimismo la potenciacion de la toxina Cry1F de Bt por los fragmentos de cadherina.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96424907P | 2007-08-10 | 2007-08-10 | |
| US95661807P | 2007-08-17 | 2007-08-17 | |
| US8495108P | 2008-07-30 | 2008-07-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR067909A1 true AR067909A1 (es) | 2009-10-28 |
Family
ID=40351113
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP080103504 AR067909A1 (es) | 2007-08-10 | 2008-08-11 | Peptidos modificados que tienen efectos mejoradores de toxinas |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9127076B2 (es) |
| EP (1) | EP2188305A4 (es) |
| AR (1) | AR067909A1 (es) |
| AU (1) | AU2008286962A1 (es) |
| BR (1) | BRPI0815379A2 (es) |
| MX (1) | MX2010001668A (es) |
| WO (1) | WO2009023639A1 (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101821395B (zh) * | 2007-10-10 | 2013-11-06 | 阿森尼克斯公司 | 编码cry1ac的合成基因 |
| CN102392029A (zh) * | 2009-12-03 | 2012-03-28 | 中国农业科学院植物保护研究所 | 改造的mcry2Ab4基因及其应用 |
| BR112017003919A2 (pt) * | 2014-08-29 | 2018-03-06 | Basf Agro Bv | misturas pesticidas, uso de misturas pesticidas, métodos de controle de pragas e usos de teflubenzuron e de clorfenapir |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20010082543A (ko) * | 1998-05-01 | 2001-08-30 | 추후제출 | Ｄｎａ 재편성을 이용한 내병충성 유전자의 최적화 방법 |
| WO2005070214A2 (en) * | 2004-01-22 | 2005-08-04 | The University Of Georgia Research Foundation, Inc. | Peptides for inhibiting insects |
-
2008
- 2008-08-11 WO PCT/US2008/072812 patent/WO2009023639A1/en active Application Filing
- 2008-08-11 AU AU2008286962A patent/AU2008286962A1/en not_active Abandoned
- 2008-08-11 US US12/672,972 patent/US9127076B2/en active Active
- 2008-08-11 BR BRPI0815379A patent/BRPI0815379A2/pt not_active IP Right Cessation
- 2008-08-11 AR ARP080103504 patent/AR067909A1/es not_active Application Discontinuation
- 2008-08-11 EP EP08797629A patent/EP2188305A4/en not_active Withdrawn
- 2008-08-11 MX MX2010001668A patent/MX2010001668A/es active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| MX2010001668A (es) | 2010-04-21 |
| WO2009023639A1 (en) | 2009-02-19 |
| EP2188305A4 (en) | 2010-08-18 |
| AU2008286962A1 (en) | 2009-02-19 |
| US9127076B2 (en) | 2015-09-08 |
| EP2188305A1 (en) | 2010-05-26 |
| BRPI0815379A2 (pt) | 2017-05-23 |
| US20120220521A1 (en) | 2012-08-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |