AR066980A1 - ANTIHELMINTIC DERIVATIVES OF BENZO (D) ISOXAZOLIL BENZAMIDA - Google Patents

ANTIHELMINTIC DERIVATIVES OF BENZO (D) ISOXAZOLIL BENZAMIDA

Info

Publication number
AR066980A1
AR066980A1 ARP080102514A ARP080102514A AR066980A1 AR 066980 A1 AR066980 A1 AR 066980A1 AR P080102514 A ARP080102514 A AR P080102514A AR P080102514 A ARP080102514 A AR P080102514A AR 066980 A1 AR066980 A1 AR 066980A1
Authority
AR
Argentina
Prior art keywords
trifluoromethyloxy
halo
trifluoromethyl
alkyl
hydrogen
Prior art date
Application number
ARP080102514A
Other languages
Spanish (es)
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of AR066980A1 publication Critical patent/AR066980A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics

Abstract

Composiciones que comprenden dichos compuestos novedosos, procesos para preparar dichos compuestos y composiciones, y el uso de los mismos como medicina, en particular en el tratamiento, control y prevencion de infecciones por endo- y ectoparásitos en animales de sangre caliente. Reivindicacion 1: Compuesto de formula (1) incluyendo cualquier forma estereoquímicamente isomérica del mismo donde cada uno de R1, R2, R3, R4, y R5 se selecciona independientemente uno del otro entre hidrogeno, halo, hidroxi, alquilo C1-6, alquiIoxi C1-6, trifluorometilo, trifluorometiloxi; alquilcarbonilo C1-4, alquiloxicarbonilo C1-4, ciano, nitro, y amino; R6 es hidrogeno, halo, alquiIo C1-6, alquiloxi C1-6, trifluorometilo, o trifluorometiloxi, y R7 es hidrogeno, halo, alquiIo C1-6, alquiloxi C1-6, trifluorometilo, o trifluorometiloxi, o una sal de adicion de ácido aceptable para uso farmacéutico del mismo, o un solvato del mismo.Compositions comprising said novel compounds, processes for preparing said compounds and compositions, and the use thereof as medicine, in particular in the treatment, control and prevention of endo- and ectoparasite infections in warm-blooded animals. Claim 1: Compound of formula (1) including any stereochemically isomeric form thereof wherein each of R1, R2, R3, R4, and R5 is independently selected from each other from hydrogen, halo, hydroxy, C1-6 alkyl, C1-alkoxy -6, trifluoromethyl, trifluoromethyloxy; C 1-4 alkylcarbonyl, C 1-4 alkyloxycarbonyl, cyano, nitro, and amino; R6 is hydrogen, halo, C1-6 alkyl, C1-6 alkyloxy, trifluoromethyl, or trifluoromethyloxy, and R7 is hydrogen, halo, C1-6 alkyl, C1-6 alkyloxy, trifluoromethyl, or trifluoromethyloxy, or an acid addition salt acceptable for pharmaceutical use thereof, or a solvate thereof.

ARP080102514A 2007-06-15 2008-06-12 ANTIHELMINTIC DERIVATIVES OF BENZO (D) ISOXAZOLIL BENZAMIDA AR066980A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP07110338 2007-06-15

Publications (1)

Publication Number Publication Date
AR066980A1 true AR066980A1 (en) 2009-09-23

Family

ID=38603183

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP080102514A AR066980A1 (en) 2007-06-15 2008-06-12 ANTIHELMINTIC DERIVATIVES OF BENZO (D) ISOXAZOLIL BENZAMIDA

Country Status (5)

Country Link
AR (1) AR066980A1 (en)
CL (1) CL2008001765A1 (en)
PA (1) PA8783901A1 (en)
TW (1) TW200916100A (en)
WO (1) WO2008152081A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102206152A (en) * 2011-04-12 2011-10-05 浙江荣耀化工有限公司 Method for chemically synthesizing 3,5-diio-2-hydroxybenzene formyl chloride

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE621597A (en) *
ZA731553B (en) * 1972-03-07 1974-10-30 Janssen Pharmaceutica Nv Salicylanilide derivatives
DE2220629C3 (en) * 1972-04-27 1981-01-22 Bayer Ag, 5090 Leverkusen Benzisoxazolo (thiono) phosphorus (phosphonic) acid esters, process for their preparation and their use as insecticides and acaricides
US4005218A (en) * 1975-03-18 1977-01-25 Janssen Pharmaceutica N.V. Antiparasitic salicylanilide derivatives
US4212865A (en) * 1978-12-26 1980-07-15 Riker Laboratories, Inc. Amine derivatives of 2-nitro-3-phenylbenzofuran
US5256681A (en) * 1989-03-15 1993-10-26 Janssen Pharmaceutica N.V. [5(6)-(benzisoxa-,benzisothia-or indazol-3-yl)-1H-benzimidazol-2-yl]carbamates

Also Published As

Publication number Publication date
WO2008152081A3 (en) 2009-05-28
TW200916100A (en) 2009-04-16
CL2008001765A1 (en) 2008-12-19
PA8783901A1 (en) 2009-01-23
WO2008152081A2 (en) 2008-12-18

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