AR062593A1 - 1 - {[5- (4-CHLOROPHENYL) -1- (2,4-DICHLOROPHENYL) -4-METHYL-1H-PIRAZOL-3-IL] CARBONIL} -PIPERIDINE AND PROCESS TO PREPARE SUCH COMPOUND; PROCESS TO ANALYZE THE PURITY OF RIMONABANT, PROCESS TO PREPARE RIMONABANT, RIMONABANT OBTAINED BY MEANS OF THIS PROCESS AND FORMULATIONS. - Google Patents

1 - {[5- (4-CHLOROPHENYL) -1- (2,4-DICHLOROPHENYL) -4-METHYL-1H-PIRAZOL-3-IL] CARBONIL} -PIPERIDINE AND PROCESS TO PREPARE SUCH COMPOUND; PROCESS TO ANALYZE THE PURITY OF RIMONABANT, PROCESS TO PREPARE RIMONABANT, RIMONABANT OBTAINED BY MEANS OF THIS PROCESS AND FORMULATIONS.

Info

Publication number
AR062593A1
AR062593A1 ARP070103847A AR062593A1 AR 062593 A1 AR062593 A1 AR 062593A1 AR P070103847 A ARP070103847 A AR P070103847A AR 062593 A1 AR062593 A1 AR 062593A1
Authority
AR
Argentina
Prior art keywords
rimonabant
prepare
dichlorophenyl
chlorophenyl
piperidine
Prior art date
Application number
Other languages
Spanish (es)
Inventor
Velez Monica Benito
Stephen Winter
Lopez Ernesto Duran
Original Assignee
Medichem Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medichem Sa filed Critical Medichem Sa
Publication of AR062593A1 publication Critical patent/AR062593A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Abstract

Un proceso para preparar rimonabant. En particular, la invencion se relaciona con minimizar la presencia y los efectos de determinados productos secundarios e impurezas presentes en el rimonabant que tiene lugar durante el sistema de rimonabant. Reivindicacion 1: Un compuesto caracterizado porque es 1-{[5-(4-clorofenil)-1-(2,4-diclorofenil)-4-metil-1H-pirazol-3-il]carbonil}piperidina (Formula III) y sus solvatos del mismo.A process to prepare rimonabant. In particular, the invention relates to minimizing the presence and effects of certain secondary products and impurities present in the rimonabant that takes place during the rimonabant system. Claim 1: A compound characterized in that it is 1 - {[5- (4-chlorophenyl) -1- (2,4-dichlorophenyl) -4-methyl-1 H -pyrazol-3-yl] carbonyl} piperidine (Formula III) and His solvates of it.

ARP070103847 2006-08-29 2007-08-29 1 - {[5- (4-CHLOROPHENYL) -1- (2,4-DICHLOROPHENYL) -4-METHYL-1H-PIRAZOL-3-IL] CARBONIL} -PIPERIDINE AND PROCESS TO PREPARE SUCH COMPOUND; PROCESS TO ANALYZE THE PURITY OF RIMONABANT, PROCESS TO PREPARE RIMONABANT, RIMONABANT OBTAINED BY MEANS OF THIS PROCESS AND FORMULATIONS. AR062593A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US84069506P 2006-08-29 2006-08-29
US92409607P 2007-04-30 2007-04-30

Publications (1)

Publication Number Publication Date
AR062593A1 true AR062593A1 (en) 2008-11-19

Family

ID=39283251

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP070103847 AR062593A1 (en) 2006-08-29 2007-08-29 1 - {[5- (4-CHLOROPHENYL) -1- (2,4-DICHLOROPHENYL) -4-METHYL-1H-PIRAZOL-3-IL] CARBONIL} -PIPERIDINE AND PROCESS TO PREPARE SUCH COMPOUND; PROCESS TO ANALYZE THE PURITY OF RIMONABANT, PROCESS TO PREPARE RIMONABANT, RIMONABANT OBTAINED BY MEANS OF THIS PROCESS AND FORMULATIONS.

Country Status (2)

Country Link
AR (1) AR062593A1 (en)
WO (1) WO2008044153A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008062480A2 (en) * 2006-11-24 2008-05-29 Ind-Swift Laboratories Limited An improved process for the preparation of rimonabant
WO2008088900A2 (en) * 2007-01-18 2008-07-24 Teva Pharmaceutical Industries Ltd. Polymorphic forms of rimonabant base and processes for preparation thereof
CN105548161B (en) * 2015-12-10 2018-01-30 山东省食品药品检验研究院 A kind of quick determination method of Rimonabant

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2831883B1 (en) * 2001-11-08 2004-07-23 Sanofi Synthelabo POLYMORPHIC FORM OF RIMONABANT, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME

Also Published As

Publication number Publication date
WO2008044153A2 (en) 2008-04-17
WO2008044153A3 (en) 2008-10-09

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