AR062452A1 - Composiciones en nanoparticulas - Google Patents
Composiciones en nanoparticulasInfo
- Publication number
- AR062452A1 AR062452A1 ARP070103620A ARP070103620A AR062452A1 AR 062452 A1 AR062452 A1 AR 062452A1 AR P070103620 A ARP070103620 A AR P070103620A AR P070103620 A ARP070103620 A AR P070103620A AR 062452 A1 AR062452 A1 AR 062452A1
- Authority
- AR
- Argentina
- Prior art keywords
- nanoparticles
- polymeric
- therapeutic agent
- therapy
- mammalian subject
- Prior art date
Links
- 239000002105 nanoparticle Substances 0.000 title abstract 7
- 239000000203 mixture Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 abstract 3
- 239000011248 coating agent Substances 0.000 abstract 2
- 238000000576 coating method Methods 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 229940124597 therapeutic agent Drugs 0.000 abstract 2
- 238000002560 therapeutic procedure Methods 0.000 abstract 2
- 150000001768 cations Chemical class 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/5115—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
- A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
- A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Nanotechnology (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Método de terapía basada en nanopartículas para un sujeto mamífero. El método utiliza nanopartículas, y/o nanopartículas con superficies externas que contienen una fraccion de afinidad efectiva para enlazarse específicamente con una superficie biologica hacia la cual se dirige la terapia, y un recubrimiento polimérico hidrofílico. El recubrimiento polimérico hidrofílico se forma de cadenas poliméricas ya sea covalentemente enlazadas o bien adsorbidas superficialmente a los componente poliméricos. Después de que se alcanza una biodistribucion deseada de las nanopartículas, el agente de afinidad se enlaza con la superficie objetivo, y ayuda a internalizar las nanopartículas. Reivindicacion 1: Un método para administrar un agente terapéutico a un sujeto mamífero, el cual comprende administrar sistémicamente al sujeto, una composicion de nanopartículas que comprende una matriz polimérica junto con el cation divalente que contiene un agente terapéutico.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US82267406P | 2006-08-17 | 2006-08-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR062452A1 true AR062452A1 (es) | 2008-11-12 |
Family
ID=39313134
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP070103620A AR062452A1 (es) | 2006-08-17 | 2007-08-15 | Composiciones en nanoparticulas |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20100166865A1 (es) |
| EP (1) | EP2054043A2 (es) |
| JP (1) | JP2010501004A (es) |
| KR (1) | KR20090041437A (es) |
| CN (1) | CN101500546A (es) |
| AR (1) | AR062452A1 (es) |
| AU (1) | AU2007319701A1 (es) |
| BR (1) | BRPI0716046A2 (es) |
| CA (1) | CA2659407A1 (es) |
| CL (1) | CL2007002371A1 (es) |
| MX (1) | MX2009001630A (es) |
| PE (1) | PE20080899A1 (es) |
| RU (1) | RU2009109353A (es) |
| TW (1) | TW200815047A (es) |
| WO (1) | WO2008060734A2 (es) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5848127B2 (ja) | 2008-08-13 | 2016-01-27 | カリフォルニア インスティテュート オブ テクノロジー | 担体ナノ粒子ならびに関連する組成物、方法およびシステム |
| WO2011133685A2 (en) * | 2010-04-21 | 2011-10-27 | President And Fellows Of Harvard College | Nanoparticle targeting to ischemia for imaging and therapy |
| WO2011159951A2 (en) * | 2010-06-17 | 2011-12-22 | Sanford-Burnham Medical Research Institute | Targeting tumor associated macrophages using bisphosphonate-loaded particles |
| US9327037B2 (en) | 2011-02-08 | 2016-05-03 | The Johns Hopkins University | Mucus penetrating gene carriers |
| US9907758B2 (en) | 2012-01-09 | 2018-03-06 | Panjab University Department Of Biotechnology (Dbt) | Process for preparing solid lipid sustained release nanoparticles for delivery of vitamins |
| EP2625966A1 (en) | 2012-02-13 | 2013-08-14 | Bionanoplus, S.L. | Nanoparticles comprising a vegetable hydrophobic protein and a water miscible non-volatile organic solvent and uses thereof |
| WO2014124006A1 (en) * | 2013-02-05 | 2014-08-14 | The Johns Hopkins University | Nanoparticles for magnetic resonance imaging tracking and methods of making and using thereof |
| US9468681B2 (en) | 2013-03-01 | 2016-10-18 | California Institute Of Technology | Targeted nanoparticles |
| CN105377942B (zh) * | 2013-05-14 | 2018-07-31 | 加州理工学院 | 通过跨越血脑屏障的纳米颗粒递送治疗剂和显像剂的方法 |
| WO2015175545A1 (en) | 2014-05-12 | 2015-11-19 | The Johns Hopkins University | Highly stable biodegradable gene vector platforms for overcoming biological barriers |
| KR20170106460A (ko) | 2015-01-27 | 2017-09-20 | 더 존스 홉킨스 유니버시티 | 점막표면에서 활성제의 향상된 수송을 위한 저장성 하이드로겔 제제 |
| EP3317323B1 (en) | 2015-07-01 | 2021-05-26 | California Institute of Technology | Cationic mucic acid polymer-based delivery systems |
| WO2017019792A1 (en) * | 2015-07-27 | 2017-02-02 | The Texas A&M University System | Surface active nanosystems |
| WO2017100533A1 (en) * | 2015-12-09 | 2017-06-15 | Board Of Regents, The University Of Texas System | Polymeric drug delivery systems for treatment of disease |
| EP4069707A4 (en) | 2019-12-04 | 2023-12-06 | Dantari, Inc. | PROCESSES AND COMPOSITIONS FOR THE SYNTHESIS OF THERAPEUTIC NANOPARTICLES |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1021168A4 (en) * | 1997-10-09 | 2006-08-30 | Univ Vanderbilt | MICRO AND NANOAPARTICULAR, POLYMERIC ADMINISTRATION SYSTEM |
| US7008645B2 (en) * | 1998-07-14 | 2006-03-07 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Method of inhibiting restenosis using bisphosphonates |
| US6558702B2 (en) * | 2001-04-13 | 2003-05-06 | Alkermes Controlled Therapeutics, Inc. | Method of modifying the release profile of sustained release compositions |
| KR100648515B1 (ko) * | 2004-05-04 | 2006-11-27 | (주)아모레퍼시픽 | 비스포스포네이트-함유 고분자 미립구를 포함하는 골-관련질환 치료 또는 예방용 서방 효과를 갖는 주사제 |
| JP4885846B2 (ja) * | 2004-05-06 | 2012-02-29 | サムヤン コーポレーション | 両親性ブロック共重合体及びポリ乳酸誘導体を含む高分子薬物担体に基づいた生物活性剤の細胞内伝達システム |
| EP1865928A1 (en) * | 2005-03-17 | 2007-12-19 | Elan Pharma International Limited | Nanoparticulate biphosphonate compositions |
-
2007
- 2007-08-15 WO PCT/US2007/075968 patent/WO2008060734A2/en active Application Filing
- 2007-08-15 EP EP07868331A patent/EP2054043A2/en not_active Withdrawn
- 2007-08-15 AR ARP070103620A patent/AR062452A1/es unknown
- 2007-08-15 AU AU2007319701A patent/AU2007319701A1/en not_active Abandoned
- 2007-08-15 RU RU2009109353/15A patent/RU2009109353A/ru not_active Application Discontinuation
- 2007-08-15 CN CNA2007800298042A patent/CN101500546A/zh active Pending
- 2007-08-15 KR KR1020097005377A patent/KR20090041437A/ko not_active Application Discontinuation
- 2007-08-15 US US12/376,458 patent/US20100166865A1/en not_active Abandoned
- 2007-08-15 MX MX2009001630A patent/MX2009001630A/es not_active Application Discontinuation
- 2007-08-15 JP JP2009524777A patent/JP2010501004A/ja active Pending
- 2007-08-15 CA CA002659407A patent/CA2659407A1/en not_active Abandoned
- 2007-08-15 BR BRPI0716046-1A2A patent/BRPI0716046A2/pt not_active Application Discontinuation
- 2007-08-15 PE PE2007001099A patent/PE20080899A1/es not_active Application Discontinuation
- 2007-08-16 CL CL200702371A patent/CL2007002371A1/es unknown
- 2007-08-16 TW TW096130347A patent/TW200815047A/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2007319701A1 (en) | 2008-05-22 |
| TW200815047A (en) | 2008-04-01 |
| CL2007002371A1 (es) | 2008-08-08 |
| WO2008060734A3 (en) | 2008-07-10 |
| BRPI0716046A2 (pt) | 2013-09-17 |
| US20100166865A1 (en) | 2010-07-01 |
| JP2010501004A (ja) | 2010-01-14 |
| MX2009001630A (es) | 2009-02-23 |
| PE20080899A1 (es) | 2008-06-25 |
| CA2659407A1 (en) | 2008-05-22 |
| KR20090041437A (ko) | 2009-04-28 |
| WO2008060734A2 (en) | 2008-05-22 |
| RU2009109353A (ru) | 2010-09-27 |
| CN101500546A (zh) | 2009-08-05 |
| EP2054043A2 (en) | 2009-05-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR062452A1 (es) | Composiciones en nanoparticulas | |
| GT200600391A (es) | Composiciones de liposomas | |
| BRPI0616071B8 (pt) | métodos de revestir uma micropartícula cristalina pré-formada em suspensão com um agente ativo | |
| ES2523589T3 (es) | Procedimiento para el revestimiento de superficies metálicas con una composición de material lubricante | |
| BR112012031161A2 (pt) | composições de enxerto não incrustante, antimicrobiano, antitrombogênico | |
| BRPI0912020A2 (pt) | composições e métodos de incorporação de fotocatalisadores | |
| BR0204406A (pt) | Revestimento, partìcula compósita, composição de revestimento, processo para preparar uma partìcula compósita, dispersão aquosa, dispersão de partìculas compósitas, processos para formar partìculas compósitas, e para preparar uma dispersão aquosa, e, composição aquosa | |
| AR065646A1 (es) | Procedimiento para el recubrimiento de superficies metalicas con una composicion acuosa que contiene polimeros, la composicion acuosa y el uso de los substratos recubiertos | |
| WO2008127743A3 (en) | Composition for targeted drug delivery and controlled release | |
| AR059856A1 (es) | Dispersiones acuosas de particulas encerradas en un polimero, las composiciones para recubrimiento y sustratos recubiertos relacionados | |
| WO2006129085A3 (en) | High affinity melan-a t cell receptors | |
| BR0116842A (pt) | Revestimentos para modificação de superfìcies duras e processos para a aplicação dos mesmos | |
| BR0000982A (pt) | Correia de transmissão de potência | |
| SG160436A1 (en) | Polymer interlayers comprising skin layers | |
| BRPI0510684A (pt) | composições para adiministração tópica ou transdérmica de agente anticolinérgico ou antiespasmódico e uso dos respectivos compostos | |
| AR069979A1 (es) | Metodo para disminuir los efectos secundarios citotoxicos y mejorar la eficacia de los inmunoconjugados | |
| BRPI0923859B8 (pt) | composição de agente de diagnóstico, e, método para a produção das nanopartículas | |
| WO2010060104A3 (en) | Implantable liposome embedded matrix composition, uses thereof, and polycaprolactone praticles as scaffolds for tissue regeneration | |
| WO2008075366A3 (en) | Novel conjugates of polyunsaturated fatty acids with amines and therapeutic uses thereof | |
| DE60112967D1 (de) | Pulverlacke mit niedrigem glanz | |
| BRPI0905369B8 (pt) | composição farmacêutica, uso da composição farmacêutica e kit compartimentado | |
| BRPI0517902A (pt) | combinação de gel/sìlica precipitada produzida in situ, e, formulação de dentifrìcio | |
| WO2007112272A3 (en) | Formulations of low dose diclofenac and beta-cyclodextrin | |
| BRPI0511355A (pt) | composição para aplicação tópica na pele de mamìferos, seu uso, métodos para confecção de composições, método para o tratamento da psorìase e método para o tratamento do eczema | |
| BRPI0505448A (pt) | dispositivo de condicionamento e seu uso |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |