AR058293A1 - PROFARMATIC SALTS AND FORMULATIONS OF 1- [5- (4-AMINO-7-ISOPROPIL-7H-PIRROLO [2,3-D] PIRIMIDIN-5-CARBONIL) -2-METOXI-PHENIL] -3- (2,4- DICLOR-PHENYL) - Google Patents

PROFARMATIC SALTS AND FORMULATIONS OF 1- [5- (4-AMINO-7-ISOPROPIL-7H-PIRROLO [2,3-D] PIRIMIDIN-5-CARBONIL) -2-METOXI-PHENIL] -3- (2,4- DICLOR-PHENYL)

Info

Publication number
AR058293A1
AR058293A1 ARP060105422A ARP060105422A AR058293A1 AR 058293 A1 AR058293 A1 AR 058293A1 AR P060105422 A ARP060105422 A AR P060105422A AR P060105422 A ARP060105422 A AR P060105422A AR 058293 A1 AR058293 A1 AR 058293A1
Authority
AR
Argentina
Prior art keywords
profarmatic
diclor
isopropil
carbonil
phenil
Prior art date
Application number
ARP060105422A
Other languages
Spanish (es)
Inventor
Tracy Lee Boyden
Douglas Alan Lorenza
Feng Guo
Susan Deborah Lagreca
Franzanne Vreeland
Ravi Mysore Shanker
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of AR058293A1 publication Critical patent/AR058293A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Abstract

La presente se refiere a compuestos de la formula (1) o una sal farmacéuticamente aceptable, profármaco o hidratos de los mismos. La presente también se refiere a composiciones farmacéuticas que contienen los compuestos de formula (1) y a métodos para tratar trastornos hiperproliferativos en un mamífero por medio de la administracion de los compuestos de formula (1).This refers to compounds of the formula (1) or a pharmaceutically acceptable salt, prodrug or hydrates thereof. This also refers to pharmaceutical compositions containing the compounds of formula (1) and to methods for treating hyperproliferative disorders in a mammal by administration of the compounds of formula (1).

ARP060105422A 2005-12-09 2006-12-07 PROFARMATIC SALTS AND FORMULATIONS OF 1- [5- (4-AMINO-7-ISOPROPIL-7H-PIRROLO [2,3-D] PIRIMIDIN-5-CARBONIL) -2-METOXI-PHENIL] -3- (2,4- DICLOR-PHENYL) AR058293A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US74907005P 2005-12-09 2005-12-09

Publications (1)

Publication Number Publication Date
AR058293A1 true AR058293A1 (en) 2008-01-30

Family

ID=38123252

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP060105422A AR058293A1 (en) 2005-12-09 2006-12-07 PROFARMATIC SALTS AND FORMULATIONS OF 1- [5- (4-AMINO-7-ISOPROPIL-7H-PIRROLO [2,3-D] PIRIMIDIN-5-CARBONIL) -2-METOXI-PHENIL] -3- (2,4- DICLOR-PHENYL)

Country Status (8)

Country Link
AR (1) AR058293A1 (en)
DO (1) DOP2006000271A (en)
GT (1) GT200600496A (en)
NL (1) NL2000337A1 (en)
PE (1) PE20071037A1 (en)
TW (1) TW200733965A (en)
UY (1) UY29991A1 (en)
WO (1) WO2007066189A2 (en)

Families Citing this family (28)

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WO2009050291A2 (en) * 2007-10-19 2009-04-23 Abbott Gmbh & Co. Kg Solid dispersion product of n-aryl urea-based drugs
CL2008003092A1 (en) * 2007-10-19 2009-11-27 Abbott Gmbh & Co Kg Solid dispersion product comprising an active agent derived from n-aryl urea, a matrix-forming agent selected from cyclodextrins, polymers, lipids and a non-ionic surfactant; process for preparing said dispersion product; and a pharmaceutical dosage form comprising it.
WO2010045542A2 (en) * 2008-10-16 2010-04-22 The Regents Of The University Of California Fused ring heteroaryl kinase inhibitors
BR112012016376A2 (en) 2009-12-30 2019-09-24 Arqule Inc substituted pyrrolo-aminopyrimide compounds
JP5847813B2 (en) * 2010-06-23 2016-01-27 シマベイ セラピューティクス， インコーポレーテッド Composition of 5-ethyl-2- {4- [4- (4-tetrazol-1-yl-phenoxymethyl) -thiazol-2-yl] -piperidin-1-yl} -pyrimidine
WO2012088266A2 (en) 2010-12-22 2012-06-28 Incyte Corporation Substituted imidazopyridazines and benzimidazoles as inhibitors of fgfr3
CA2846496C (en) 2011-09-02 2020-07-14 The Regents Of The University Of California Substituted pyrazolo[3,4-d]pyrimidines and uses thereof
US20140004192A1 (en) * 2012-04-13 2014-01-02 Ziopharm Oncology, Inc. Pharmaceutical formulations of indibulin and uses thereof
BR112014030812B1 (en) 2012-06-13 2022-11-08 Incyte Holdings Corporation SUBSTITUTED TRICYCLIC COMPOUNDS AS FGFR INHIBITORS, THEIR USES, PHARMACEUTICAL COMPOSITION AND METHOD FOR INHIBITING A FGFR ENZYME
US9388185B2 (en) 2012-08-10 2016-07-12 Incyte Holdings Corporation Substituted pyrrolo[2,3-b]pyrazines as FGFR inhibitors
KR20150061651A (en) 2012-09-26 2015-06-04 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 Modulation of ire1
US9266892B2 (en) 2012-12-19 2016-02-23 Incyte Holdings Corporation Fused pyrazoles as FGFR inhibitors
SG10201708520YA (en) 2013-04-19 2017-12-28 Incyte Corp Bicyclic heterocycles as fgfr inhibitors
US10851105B2 (en) 2014-10-22 2020-12-01 Incyte Corporation Bicyclic heterocycles as FGFR4 inhibitors
MA41551A (en) 2015-02-20 2017-12-26 Incyte Corp BICYCLIC HETEROCYCLES USED AS FGFR4 INHIBITORS
AU2016219822B2 (en) 2015-02-20 2020-07-09 Incyte Holdings Corporation Bicyclic heterocycles as FGFR inhibitors
WO2016134294A1 (en) 2015-02-20 2016-08-25 Incyte Corporation Bicyclic heterocycles as fgfr4 inhibitors
CN107722012B (en) * 2016-08-11 2020-05-29 斯福瑞（南通）制药有限公司 Process for preparing 4-chloro-7H-pyrrolo [2,3-d ] pyrimidines
AR111960A1 (en) 2017-05-26 2019-09-04 Incyte Corp CRYSTALLINE FORMS OF A FGFR INHIBITOR AND PROCESSES FOR ITS PREPARATION
KR20210018265A (en) 2018-05-04 2021-02-17 인사이트 코포레이션 Solid form of FGFR inhibitor and method for preparing same
SG11202010882XA (en) 2018-05-04 2020-11-27 Incyte Corp Salts of an fgfr inhibitor
US11628162B2 (en) 2019-03-08 2023-04-18 Incyte Corporation Methods of treating cancer with an FGFR inhibitor
US11591329B2 (en) 2019-07-09 2023-02-28 Incyte Corporation Bicyclic heterocycles as FGFR inhibitors
JP2022552324A (en) 2019-10-14 2022-12-15 インサイト・コーポレイション Bicyclic heterocycles as FGFR inhibitors
WO2021076728A1 (en) 2019-10-16 2021-04-22 Incyte Corporation Bicyclic heterocycles as fgfr inhibitors
CA3163875A1 (en) 2019-12-04 2021-06-10 Incyte Corporation Tricyclic heterocycles as fgfr inhibitors
EP4069695A1 (en) 2019-12-04 2022-10-12 Incyte Corporation Derivatives of an fgfr inhibitor
AR126102A1 (en) 2021-06-09 2023-09-13 Incyte Corp TRICYCLIC HETEROCYCLES AS FGFR INHIBITORS

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0901786T3 (en) * 1997-08-11 2007-10-08 Pfizer Prod Inc Solid pharmaceutical dispersions with increased bioavailability
UA80171C2 (en) * 2002-12-19 2007-08-27 Pfizer Prod Inc Pyrrolopyrimidine derivatives

Also Published As

Publication number Publication date
NL2000337A1 (en) 2007-06-12
WO2007066189A3 (en) 2008-08-14
GT200600496A (en) 2007-07-17
DOP2006000271A (en) 2007-08-15
WO2007066189A2 (en) 2007-06-14
PE20071037A1 (en) 2007-11-19
TW200733965A (en) 2007-09-16
UY29991A1 (en) 2007-07-31

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