AR052161A1 - DERIVATIVES OF N- [1- (CYANOMETIL-CARBAMOIL) -CICLOHEXIL] -4- (4-PROPIL-PIPERAZIN-1-IL) -BENZAMIDA - Google Patents

DERIVATIVES OF N- [1- (CYANOMETIL-CARBAMOIL) -CICLOHEXIL] -4- (4-PROPIL-PIPERAZIN-1-IL) -BENZAMIDA

Info

Publication number
AR052161A1
AR052161A1 ARP050105249A ARP050105249A AR052161A1 AR 052161 A1 AR052161 A1 AR 052161A1 AR P050105249 A ARP050105249 A AR P050105249A AR P050105249 A ARP050105249 A AR P050105249A AR 052161 A1 AR052161 A1 AR 052161A1
Authority
AR
Argentina
Prior art keywords
piperazin
cyanometil
ciclohexil
benzamida
carbamoil
Prior art date
Application number
ARP050105249A
Other languages
Spanish (es)
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of AR052161A1 publication Critical patent/AR052161A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Composiciones farmacéuticas que los contienen, usos y método de preparacion. Reivindicacion 1: Maleato de hidrogeno de N-[1-(cianometil-carbamoil)-ciclohexil]-4-(4-propil-piperazin-1-il)-benzamida.Pharmaceutical compositions containing them, uses and method of preparation. Claim 1: N- [1- (Cyanomethyl-carbamoyl) -cyclohexyl] -4- (4-propyl-piperazin-1-yl) -benzamide hydrogen maleate.

ARP050105249A 2004-12-14 2005-12-14 DERIVATIVES OF N- [1- (CYANOMETIL-CARBAMOIL) -CICLOHEXIL] -4- (4-PROPIL-PIPERAZIN-1-IL) -BENZAMIDA AR052161A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0427380.1A GB0427380D0 (en) 2004-12-14 2004-12-14 Organic compounds

Publications (1)

Publication Number Publication Date
AR052161A1 true AR052161A1 (en) 2007-03-07

Family

ID=34090027

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP050105249A AR052161A1 (en) 2004-12-14 2005-12-14 DERIVATIVES OF N- [1- (CYANOMETIL-CARBAMOIL) -CICLOHEXIL] -4- (4-PROPIL-PIPERAZIN-1-IL) -BENZAMIDA

Country Status (6)

Country Link
AR (1) AR052161A1 (en)
GB (1) GB0427380D0 (en)
GT (1) GT200500365A (en)
PE (1) PE20060742A1 (en)
TW (1) TW200635910A (en)
WO (1) WO2006063762A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008104271A2 (en) 2007-02-28 2008-09-04 Sanofi-Aventis Imaging probes
EP2262783A2 (en) * 2008-02-21 2010-12-22 Sanofi-Aventis Covalently binding imaging probes

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ID24931A (en) * 1997-11-05 2000-08-31 Novartis Ag NITRIL PROVIDED
GB0003111D0 (en) * 2000-02-10 2000-03-29 Novartis Ag Organic compounds
CA2532948A1 (en) * 2003-07-21 2005-02-17 Novartis Ag Combinations of a cathepsin k inhibitor and a bisphophonate in the treatment of bone metastasis, tumor growth and tumor-induced bone loss
EP1686995A1 (en) * 2003-11-19 2006-08-09 Novartis AG Use of cathepsin k inhibitors for treating of severe bone loss diseases

Also Published As

Publication number Publication date
WO2006063762A1 (en) 2006-06-22
TW200635910A (en) 2006-10-16
PE20060742A1 (en) 2006-09-08
GT200500365A (en) 2006-07-17
GB0427380D0 (en) 2005-01-19

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal