AR052060A1 - Suspensiones orales estables de azitromicina no dihidratada - Google Patents
Suspensiones orales estables de azitromicina no dihidratadaInfo
- Publication number
- AR052060A1 AR052060A1 ARP050105334A ARP050105334A AR052060A1 AR 052060 A1 AR052060 A1 AR 052060A1 AR P050105334 A ARP050105334 A AR P050105334A AR P050105334 A ARP050105334 A AR P050105334A AR 052060 A1 AR052060 A1 AR 052060A1
- Authority
- AR
- Argentina
- Prior art keywords
- azithromycin
- oral suspensions
- stable oral
- oral suspension
- conversion
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nanotechnology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Inorganic Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Medical Informatics (AREA)
- Biophysics (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Un polvo para suspension oral, y a una suspension oral preparada a partir del mismo, que comprende azitromicina no dihidratada y un excipiente estabilizante de la conversion de azitromicina, en la que dicho excipiente reduce la conversion de la forma de azitromicina, cuando se pone en suspension, en otra forma de azitromicina. Adicionalmente, un procedimiento para reducir la conversion de una forma de azitromicina no dihidratada, en una suspension oral, incluyendo al menos una ciclodextrina en dicha suspension oral.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US63821804P | 2004-12-21 | 2004-12-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR052060A1 true AR052060A1 (es) | 2007-02-28 |
Family
ID=36602128
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP050105334A AR052060A1 (es) | 2004-12-21 | 2005-12-19 | Suspensiones orales estables de azitromicina no dihidratada |
Country Status (7)
Country | Link |
---|---|
US (1) | US20100048498A1 (es) |
EP (1) | EP1830860A2 (es) |
JP (1) | JP2008524318A (es) |
AR (1) | AR052060A1 (es) |
CA (1) | CA2591744A1 (es) |
TW (1) | TW200633728A (es) |
WO (1) | WO2006067577A2 (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI478915B (zh) | 2008-10-27 | 2015-04-01 | Cellceutix Corp | 宿主防禦之合成模擬物及其用途 |
US20120101159A1 (en) * | 2009-04-27 | 2012-04-26 | Laboratorio De Aplicaciones Farmacodinamicas, S.A. | Ibuprofen lysinate oral suspension |
WO2013088274A1 (en) | 2011-12-14 | 2013-06-20 | Wockhardt Limited | Anhydrous amorphous azithromycin composition free of azithromycin dihydrate |
RU2707748C2 (ru) * | 2013-11-08 | 2019-11-29 | Активус Фарма Ко., Лтд. | Композиция водной суспензии, включающая наночастицы макролидных антибиотиков |
JP6711875B2 (ja) * | 2018-08-29 | 2020-06-17 | 日本食品化工株式会社 | マクロライド化合物の苦味抑制剤 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4474768A (en) * | 1982-07-19 | 1984-10-02 | Pfizer Inc. | N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor |
CA2245398C (en) * | 1998-08-21 | 2002-01-29 | Apotex Inc. | Azithromycin monohydrate isopropanol clathrate and methods for the manufacture thereof |
KR100603226B1 (ko) * | 1998-11-30 | 2006-08-28 | 테바 파마슈티컬 인더스트리즈 리미티드 | 아지스로마이신의 에탄올레이트, 이의 제조 방법 및 약학 조성물 |
US6861413B2 (en) * | 2001-05-22 | 2005-03-01 | Pfizer Inc. | Stable non-dihydrate azithromycin oral suspensions |
DE60232005D1 (de) * | 2001-10-18 | 2009-05-28 | Teva Pharma | Stabilisierte azithromycin-zusammensetzungen |
MXPA04005105A (es) * | 2001-12-21 | 2004-08-19 | Pfizer Prod Inc | Formulaciones de acitromicina directamente compresibles. |
GB0214277D0 (en) * | 2002-06-20 | 2002-07-31 | Biochemie Gmbh | Organic compounds |
GB0224197D0 (en) * | 2002-10-17 | 2002-11-27 | Biochemie Gmbh | Organic compounds |
US20050013835A1 (en) * | 2003-07-15 | 2005-01-20 | Pfizer Inc. | Stable non-dihydrate azithromycin oral suspensions |
-
2005
- 2005-12-09 US US11/722,279 patent/US20100048498A1/en not_active Abandoned
- 2005-12-09 EP EP05811059A patent/EP1830860A2/en not_active Withdrawn
- 2005-12-09 JP JP2007547689A patent/JP2008524318A/ja not_active Withdrawn
- 2005-12-09 CA CA002591744A patent/CA2591744A1/en not_active Abandoned
- 2005-12-09 WO PCT/IB2005/003767 patent/WO2006067577A2/en active Application Filing
- 2005-12-19 AR ARP050105334A patent/AR052060A1/es not_active Application Discontinuation
- 2005-12-20 TW TW094145377A patent/TW200633728A/zh unknown
Also Published As
Publication number | Publication date |
---|---|
JP2008524318A (ja) | 2008-07-10 |
CA2591744A1 (en) | 2006-06-29 |
WO2006067577A2 (en) | 2006-06-29 |
US20100048498A1 (en) | 2010-02-25 |
WO2006067577A3 (en) | 2006-12-28 |
TW200633728A (en) | 2006-10-01 |
EP1830860A2 (en) | 2007-09-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |