AR050345A1 - METHODS TO TREAT SUBSTANCE RELATED DISORDERS - Google Patents

METHODS TO TREAT SUBSTANCE RELATED DISORDERS

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Publication number
AR050345A1
AR050345A1 ARP050102683A AR050345A1 AR 050345 A1 AR050345 A1 AR 050345A1 AR P050102683 A ARP050102683 A AR P050102683A AR 050345 A1 AR050345 A1 AR 050345A1
Authority
AR
Argentina
Prior art keywords
substance
treatment
group
compounds
phenyl
Prior art date
Application number
Other languages
Spanish (es)
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37311740&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR050345(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of AR050345A1 publication Critical patent/AR050345A1/en

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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Método para la prevencion, tratamiento o mejora de trastornos relacionados con sustancias, en un sujeto que lo necesite y comprende la administracion al sujeto de una cantidad efectiva de un compuesto seleccionado de los compuestos de formula (1) o (2), o sus formas farmacéuticamente aceptadas donde el fenilo se sustituye en X por 1 a 5 átomos de halogeno seleccionados del grupo formado por fluor, cloro, bromo y yodo; y R1, R2, R3, R4, R5 y R6 se seleccionan de manera independiente del grupo formado por hidrogeno y alquilo C1-4; donde alquilo C1-4 se sustituye opcionalmente por fenilo (y, donde el fenilo se sustituye opcionalmente por sustituyentes independientemente seleccionados del grupo formado por halogeno, alquilo C1-4, alcoxi C1- 4, amino, nitro y ciano). Además, los métodos incluidos comprenden la co-administracion de los compuestos de la presente con uno o más compuestos conocidos para el tratamiento de trastornos inducidos por sustancias. Reivindicacion 11: El método de la reivindicacion 1, donde el método también comprende la prevencion, tratamiento y mejora de un trastorno inducido por sustancias que resulta del uso de una droga adictiva. Reivindicacion 12: El método de la reivindicacion 11, donde la droga adictiva se selecciona de heroína, opio, morfina, cocaína, anfetaminas, metanfetaminas, etanol, benzodiazepinas, metadona, oxicodona, codeina, inhalantes, barbituricos, fenciclidinas o nicotina. Reivindicacion 16: El método de la reivindicacion 14, donde el compuesto conocido para el tratamiento de trastornos inducidos por sustancias es uno o más compuestos seleccionados del grupo formado por acamprosato, naltrexona, naloxona y disulfiram.Method for the prevention, treatment or improvement of substance-related disorders, in a subject in need and comprising administering to the subject an effective amount of a compound selected from the compounds of formula (1) or (2), or their forms pharmaceutically accepted where the phenyl is substituted in X by 1 to 5 halogen atoms selected from the group consisting of fluorine, chlorine, bromine and iodine; and R1, R2, R3, R4, R5 and R6 are independently selected from the group consisting of hydrogen and C1-4 alkyl; wherein C1-4 alkyl is optionally substituted by phenyl (and, where the phenyl is optionally substituted by substituents independently selected from the group consisting of halogen, C1-4 alkyl, C1-4 alkoxy, amino, nitro and cyano). In addition, the included methods comprise co-administration of the compounds herein with one or more known compounds for the treatment of substance induced disorders. Claim 11: The method of claim 1, wherein the method also comprises the prevention, treatment and improvement of a substance-induced disorder resulting from the use of an addictive drug. Claim 12: The method of claim 11, wherein the addictive drug is selected from heroin, opium, morphine, cocaine, amphetamines, methamphetamines, ethanol, benzodiazepines, methadone, oxycodone, codeine, inhalants, barbiturates, phencyclidines or nicotine. Claim 16: The method of claim 14, wherein the compound known for the treatment of substance-induced disorders is one or more compounds selected from the group consisting of acamprosate, naltrexone, naloxone and disulfiram.

ARP050102683 2004-06-30 2005-06-29 METHODS TO TREAT SUBSTANCE RELATED DISORDERS AR050345A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US58419104P 2004-06-30 2004-06-30

Publications (1)

Publication Number Publication Date
AR050345A1 true AR050345A1 (en) 2006-10-18

Family

ID=37311740

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP050102683 AR050345A1 (en) 2004-06-30 2005-06-29 METHODS TO TREAT SUBSTANCE RELATED DISORDERS

Country Status (3)

Country Link
AR (1) AR050345A1 (en)
MY (1) MY149385A (en)
PE (1) PE20060559A1 (en)

Also Published As

Publication number Publication date
PE20060559A1 (en) 2006-08-11
MY149385A (en) 2013-08-30

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