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Priority claimed from US10/985,115external-prioritypatent/US7153961B2/en
Application filed by Bristol Myers Squibb Pharma CofiledCriticalBristol Myers Squibb Pharma Co
Publication of AR046850A1publicationCriticalpatent/AR046850A1/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
El presente proporciona la sal bencenosulfonato de 4-(bis(2-metoxietil)amino-2,7-dimetil-8-(2-metil-4-metoxifenil)-[1,5-alfa]-pirazolo-1,3,5-triazina y un polimorfo cristalino de la misma. También proporciona composiciones farmacéuticas que contienen la sal y métodos de tratamiento de los trastornos relacionados con CRF usando dicha sal. Reivindicación 2: El compuesto de la reivindicación 1 que tiene la fórmula (1), donde n es aproximadamente de 0 a aproximadamente 1.The present provides the benzenesulfonate salt of 4- (bis (2-methoxyethyl) amino-2,7-dimethyl-8- (2-methyl-4-methoxyphenyl) - [1,5-alpha] -pyrazolo-1,3, 5-triazine and a crystalline polymorph thereof It also provides pharmaceutical compositions containing the salt and methods of treating CRF-related disorders using said salt Claim 2: The compound of claim 1 having the formula (1), where n is about 0 to about 1.
ARP040104335A2004-11-102004-11-24
SALT AND CRYSTAL FORM OF THE SAME OF AN ANTAGONIST OF THE RECEIVER OF THE CORTICOTROPINE RELEASE FACTOR
AR046850A1
(en)
Substituted pyrazolospiroketone derivative compounds, acetyl-coa carboxylase inhibitors; pharmaceutical composition comprising them; use to treat or delay the progression or onset of type 2 diabetes, non-alcoholic fatty liver (hgna), or hepatic insulin resistance.
COMPOUNDS OF POLYSUSTITUTED AZETIDINS, PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM, METHOD OF PREPARATION AND USE OF THE SAME IN THE TREATMENT OF RESPIRATORY, METABOLIC DISEASES AND OF THE CENTRAL NERVOUS SYSTEM, AMONG OTHERS.