AR045847A1 - Derivados del tiazol - Google Patents
Derivados del tiazolInfo
- Publication number
- AR045847A1 AR045847A1 ARP040103514A ARP040103514A AR045847A1 AR 045847 A1 AR045847 A1 AR 045847A1 AR P040103514 A ARP040103514 A AR P040103514A AR P040103514 A ARP040103514 A AR P040103514A AR 045847 A1 AR045847 A1 AR 045847A1
- Authority
- AR
- Argentina
- Prior art keywords
- alkynyl
- cycloalkyl
- alkenyl
- aryl
- skin
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Toxicology (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Los métodos son revelados para el mejoramiento de la apariencia de la piel mediante aplicación local de derivados de tiazol los cuales inhiben la formación de productos finales de la glucosilación avanzada, rompen los entrecruces asociados a los productos finales de la glucosilación avanzada e inhiben la función de la glucosa oxidasa. Composiciones cosméticas farmacéuticas que comprenden derivados de tiazol. Reivindicación 1: Una composición cosmética o farmacéutica para aplicación local que comprenda un compuesto inhibidor o de escisión de productos de la glucosilación avanzada de la fórmula (1), en donde R1, R2 y R3 son seleccionados independientemente de H; sustituidos o no sustituidos C1-10 alquil, alquenil, alquinil, aril, cicloalquil, y grupos heterocíclicos; NH2, NRaRb; SH; SR; CN; halógeno; OH; OR; SO3, SO3R; NO2; NO; C(=O)H; C(=O)R; C(=O)OH; C(=O)OR; (=O)NRaRb; donde R es seleccionado de H, sustituidos o no sustituidos C1-10 alquil, alquenil, alquinil, aril, cicloalquil, y grupos heterocíclicos; y donde Ra y Rb son seleccionados independientemente de H, sustituidos o no sustituidos C1-10 alquil, alquenil, alquinil, aril, cicloalquil, y grupos heterocíclicos; o una sal de ellos; y un vehículo farmacéutica o cosméticamente aceptable; en el que el citado compuesto este presente en una cantidad efectiva para el mejoramiento de la apariencia de la piel cuando sea aplicado localmente en la piel. Reivindicación 13: La composición de la reivindicación 1, en la que el citado compuesto es 2-amino-4,5-dimetiltiazol o una sal de ella.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/738,412 US20050137239A1 (en) | 2003-12-17 | 2003-12-17 | Thiazole derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR045847A1 true AR045847A1 (es) | 2005-11-16 |
Family
ID=34523171
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP040103514A AR045847A1 (es) | 2003-12-17 | 2004-09-28 | Derivados del tiazol |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20050137239A1 (es) |
| EP (1) | EP1543824A3 (es) |
| JP (1) | JP2005179341A (es) |
| CN (1) | CN1636563A (es) |
| AR (1) | AR045847A1 (es) |
| AU (1) | AU2004205185B2 (es) |
| BR (1) | BRPI0404999A (es) |
| CA (1) | CA2479432A1 (es) |
| MX (1) | MXPA04012364A (es) |
| TW (1) | TW200520783A (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007013572A1 (ja) * | 2005-07-29 | 2007-02-01 | Shiseido Company, Ltd. | 毛髪はり・こし改善剤および毛髪用化粧料 |
| GB0605949D0 (en) * | 2006-03-24 | 2006-05-03 | Quest Int Serv Bv | Milk product for skin treatment |
| FR2918570B1 (fr) * | 2007-07-09 | 2012-10-05 | Engelhard Lyon | DIGLYCATION DES AGEs. |
| DE102010012594A1 (de) * | 2010-03-23 | 2011-09-29 | Beiersdorf Ag | Kosmetische oder dermatologische Zubereitungen mit einem Gehalt an einem oder mehreren Thiazolderivaten |
| MA47595A (fr) * | 2017-02-24 | 2020-01-01 | Alzheon Inc | Méthodes de traitement d'affections neurodégénératives |
| KR102076936B1 (ko) * | 2019-08-12 | 2020-02-13 | 연세대학교 산학협력단 | 티아졸 또는 이의 염을 유효성분으로 포함하는 알러지성 질환 또는 아토피 피부염 예방 또는 치료용 조성물 |
| JP2023522251A (ja) | 2020-04-24 | 2023-05-29 | バイエル・アクチエンゲゼルシヤフト | 免疫活性化のためのｄｇｋｚｅｔａ阻害剤としての置換アミノチアゾール類 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4321372A (en) * | 1980-06-16 | 1982-03-23 | Pfizer Inc. | Antiulcer thiazol-2-ylcarbamoyl-carboxylic acids, esters and amides |
| ATE245420T1 (de) * | 1995-01-18 | 2003-08-15 | Alteon Inc | Verwendung von thiazoliumverbindungen zum verhindern und umkehren der bildung von endprodukten der fortgeschrittenen glykosylierung |
| EP1785134A3 (en) * | 2000-01-19 | 2009-02-18 | Synvista Therapeutics, Inc. | Use of thiazole, imidazole and oxazole compounds for the treatment of disorders associated with protein aging |
| MXPA02008276A (es) * | 2000-02-23 | 2004-04-05 | Alteon Inc | Compuestos de tiazolio y tratamientos de trastornos asociados con el envejecimiento proteinico. |
| AU2001239754A1 (en) * | 2000-02-25 | 2001-09-03 | Avon Products Inc. | Topical compositions containing thiazolium compounds and methods of using same |
| EP1353676A4 (en) * | 2000-12-29 | 2006-05-31 | Alteon Inc | METHOD FOR THE TREATMENT OF FIBROUS OR OTHER INDICATIONS |
-
2003
- 2003-12-17 US US10/738,412 patent/US20050137239A1/en not_active Abandoned
-
2004
- 2004-08-23 AU AU2004205185A patent/AU2004205185B2/en not_active Ceased
- 2004-08-30 CA CA002479432A patent/CA2479432A1/en not_active Abandoned
- 2004-09-09 TW TW093127326A patent/TW200520783A/zh unknown
- 2004-09-28 AR ARP040103514A patent/AR045847A1/es unknown
- 2004-10-19 CN CNA200410086112XA patent/CN1636563A/zh active Pending
- 2004-11-05 JP JP2004321553A patent/JP2005179341A/ja active Pending
- 2004-11-16 BR BR0404999-3A patent/BRPI0404999A/pt not_active IP Right Cessation
- 2004-12-09 MX MXPA04012364A patent/MXPA04012364A/es not_active Application Discontinuation
- 2004-12-17 EP EP04030027A patent/EP1543824A3/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP1543824A2 (en) | 2005-06-22 |
| CN1636563A (zh) | 2005-07-13 |
| MXPA04012364A (es) | 2005-06-22 |
| TW200520783A (en) | 2005-07-01 |
| BRPI0404999A (pt) | 2005-08-30 |
| US20050137239A1 (en) | 2005-06-23 |
| CA2479432A1 (en) | 2005-06-17 |
| AU2004205185B2 (en) | 2007-11-22 |
| EP1543824A3 (en) | 2005-09-14 |
| AU2004205185A1 (en) | 2005-07-07 |
| JP2005179341A (ja) | 2005-07-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |