AR040099A1 - ENANTIOSELECTIVE HYDROGENATION, WITH HETEROGENEO CATALYST, IN THE PRESENCE OF SUPERCRITICAL FLUID - Google Patents
ENANTIOSELECTIVE HYDROGENATION, WITH HETEROGENEO CATALYST, IN THE PRESENCE OF SUPERCRITICAL FLUIDInfo
- Publication number
- AR040099A1 AR040099A1 ARP030101822A ARP030101822A AR040099A1 AR 040099 A1 AR040099 A1 AR 040099A1 AR P030101822 A ARP030101822 A AR P030101822A AR P030101822 A ARP030101822 A AR P030101822A AR 040099 A1 AR040099 A1 AR 040099A1
- Authority
- AR
- Argentina
- Prior art keywords
- reaction
- hydrogenation
- catalyst
- fluid
- reaction mixture
- Prior art date
Links
- 239000012530 fluid Substances 0.000 title abstract 5
- 238000005984 hydrogenation reaction Methods 0.000 title abstract 5
- 239000003054 catalyst Substances 0.000 title abstract 3
- 238000006243 chemical reaction Methods 0.000 abstract 5
- 239000011541 reaction mixture Substances 0.000 abstract 4
- 150000002894 organic compounds Chemical class 0.000 abstract 3
- 239000002638 heterogeneous catalyst Substances 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 238000010924 continuous production Methods 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B53/00—Asymmetric syntheses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/303—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by hydrogenation of unsaturated carbon-to-carbon bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/54—Improvements relating to the production of bulk chemicals using solvents, e.g. supercritical solvents or ionic liquids
Abstract
Un método para realizar una reacción química, que involucra la hidrogenación enantioselectiva de un substrato para obtener un producto quiral, usando un catalizador heterogéneo, bajo condiciones de flujo continuo, en un reactor de flujo continuo. La hidrogenación se lleva a cabo en la presencia de un fluido supercrítico, donde la mezcla que comprende los reactivos, el fluido y/o los productos puede tener una fase única o puede presentar varias fases. El catalizador se fija a un soporte y toma una forma ópticamente activa. Reivindicación 1: Un proceso continuo para la hidrogenación de un compuesto orgánico caracterizado porque comprende los pasos de: (a) mezclar una alimentación de un fluido inerte con una alimentación de un primer compuesto orgánico y una alimentación de hidrógeno; (b) ajustar la temperatura y la presión de la mezcla resultante en valores predeterminados de temperatura y presión cercanos o superiores al punto crítico del fluido, para producir una mezcla de reacción a partir de la cual se forma sustancialmente un único producto deseado, entre una pluralidad de posibles productos estereoisoméricos que podrían formarse a través de la hidrogenación del primer compuesto orgánico en una reacción selectiva, donde la elección de los valores predeterminados depende de los productos que pueden formarse en la reacción; (c) exponer la mezcla de reacción a un catalizador heterogéneo quiral para facilitar la reacción selectiva; y (d) retirar la mezcla de reacción, una vez finalizada la reacción, de la región del catalizador y aislar el producto deseado mediante la despresurización de la mezcla de reacción.A method for carrying out a chemical reaction, which involves the enantioselective hydrogenation of a substrate to obtain a chiral product, using a heterogeneous catalyst, under continuous flow conditions, in a continuous flow reactor. Hydrogenation is carried out in the presence of a supercritical fluid, where the mixture comprising the reagents, the fluid and / or the products may have a single phase or may have several phases. The catalyst is fixed to a support and takes an optically active form. Claim 1: A continuous process for the hydrogenation of an organic compound characterized in that it comprises the steps of: (a) mixing a feed of an inert fluid with a feed of a first organic compound and a feed of hydrogen; (b) adjust the temperature and pressure of the resulting mixture at predetermined temperature and pressure values close to or greater than the critical point of the fluid, to produce a reaction mixture from which substantially a single desired product is formed, between a plurality of possible stereoisomeric products that could be formed through the hydrogenation of the first organic compound in a selective reaction, where the choice of predetermined values depends on the products that can be formed in the reaction; (c) exposing the reaction mixture to a chiral heterogeneous catalyst to facilitate the selective reaction; and (d) removing the reaction mixture, once the reaction is complete, from the catalyst region and isolating the desired product by depressurizing the reaction mixture.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0212005.3A GB0212005D0 (en) | 2002-05-24 | 2002-05-24 | Chiral hydrogenation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR040099A1 true AR040099A1 (en) | 2005-03-16 |
Family
ID=9937364
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP030101822A AR040099A1 (en) | 2002-05-24 | 2003-05-23 | ENANTIOSELECTIVE HYDROGENATION, WITH HETEROGENEO CATALYST, IN THE PRESENCE OF SUPERCRITICAL FLUID |
Country Status (4)
| Country | Link |
|---|---|
| AR (1) | AR040099A1 (en) |
| AU (1) | AU2003244738A1 (en) |
| GB (1) | GB0212005D0 (en) |
| WO (1) | WO2003099743A1 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5051769B2 (en) | 2004-05-07 | 2012-10-17 | タレスナノ ナノテクノロジアイ ゼットアールティー． | Continuous flow laboratory hydrogenation apparatus and laboratory hydrogenation method using the apparatus |
| KR100780910B1 (en) | 2007-01-24 | 2007-11-30 | 한국에너지기술연구원 | Producing method of ni/activated carbon catalysts and hydrogen-producing system through supercritical water gasification of organic compounds using ni/activated carbon catalysts and driving method thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2336298A1 (en) * | 1998-07-01 | 2000-01-13 | Thomas Swan & Co. Ltd. | Hydroformylation reactions |
-
2002
- 2002-05-24 GB GBGB0212005.3A patent/GB0212005D0/en not_active Ceased
-
2003
- 2003-05-20 AU AU2003244738A patent/AU2003244738A1/en not_active Abandoned
- 2003-05-20 WO PCT/GB2003/002157 patent/WO2003099743A1/en not_active Application Discontinuation
- 2003-05-23 AR ARP030101822A patent/AR040099A1/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| GB0212005D0 (en) | 2002-07-03 |
| WO2003099743A1 (en) | 2003-12-04 |
| AU2003244738A1 (en) | 2003-12-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |