AR038716A1 - Procedimiento para la sintesis de cloroadenosina y metiltioadenosina - Google Patents
Procedimiento para la sintesis de cloroadenosina y metiltioadenosinaInfo
- Publication number
- AR038716A1 AR038716A1 ARP030100701A ARP030100701A AR038716A1 AR 038716 A1 AR038716 A1 AR 038716A1 AR P030100701 A ARP030100701 A AR P030100701A AR P030100701 A ARP030100701 A AR P030100701A AR 038716 A1 AR038716 A1 AR 038716A1
- Authority
- AR
- Argentina
- Prior art keywords
- chloroadenosine
- synthesis
- methyltioadenosine
- procedure
- reaction solution
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/173—Purine radicals with 2-deoxyribosyl as the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
- C22C—ALLOYS
- C22C1/00—Making non-ferrous alloys
- C22C1/08—Alloys with open or closed pores
- C22C1/083—Foaming process in molten metal other than by powder metallurgy
- C22C1/086—Gas foaming process
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Metallurgy (AREA)
- Mechanical Engineering (AREA)
- Materials Engineering (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Un procedimiento in situ para preparar cloroadenosina, en el que se hace reaccionar la adenosina en un disolvente no acuoso con un cloruro de tionilo y una piridina para formar una solución de reacción; se cambia el disolvente no acuoso por un alcohol inferior, y se anade una base a la solución de reacción; y se filtra, se lava y se seca la cloroadenosina resultante. Adicionalmente, se describe un procedimiento de dos etapas para la síntesis de metiltioadenosina usando la cloroadenosina preparada in situ.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36128402P | 2002-03-04 | 2002-03-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR038716A1 true AR038716A1 (es) | 2005-01-26 |
Family
ID=27789105
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP030100701A AR038716A1 (es) | 2002-03-04 | 2003-03-03 | Procedimiento para la sintesis de cloroadenosina y metiltioadenosina |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US20030181713A1 (es) |
| EP (1) | EP1483279A1 (es) |
| KR (1) | KR20040094761A (es) |
| CN (1) | CN1639182A (es) |
| AR (1) | AR038716A1 (es) |
| AU (1) | AU2003206011A1 (es) |
| BR (1) | BR0308091A (es) |
| CA (1) | CA2477729A1 (es) |
| GT (1) | GT200300047A (es) |
| HN (1) | HN2003000082A (es) |
| IL (1) | IL163778A0 (es) |
| MX (1) | MXPA04008550A (es) |
| PA (1) | PA8567901A1 (es) |
| PE (1) | PE20031002A1 (es) |
| PL (1) | PL370863A1 (es) |
| RU (1) | RU2004126699A (es) |
| SV (1) | SV2004001491A (es) |
| TW (1) | TW200304826A (es) |
| UY (1) | UY27693A1 (es) |
| WO (1) | WO2003074541A1 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014163150A1 (ja) * | 2013-04-05 | 2014-10-09 | ライオン株式会社 | 内服組成物 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4373122A (en) * | 1981-01-26 | 1983-02-08 | W. H. Brady Co. | Capacitance switch |
| US4373097A (en) * | 1981-04-27 | 1983-02-08 | Bioresearch S.R.L. | Process for preparing adenosine derivatives of anti-inflammatory and analgesic activity |
| US4454122A (en) * | 1981-04-27 | 1984-06-12 | Bioresearch S.R.L. | Adenosine derivatives of anti-inflammatory and analgesic activity, and therapeutic compositions which contain them as their active principle |
| JPS61171423A (ja) * | 1985-01-24 | 1986-08-02 | Advance Res & Dev Co Ltd | 抗う蝕乃至抗歯周症剤 |
| US6492349B1 (en) * | 1993-03-31 | 2002-12-10 | Nutramax Laboratories, Inc. | Aminosugar and glycosaminoglycan composition for the treatment and repair of connective tissue |
| US5872104A (en) * | 1994-12-27 | 1999-02-16 | Oridigm Corporation | Combinations and methods for reducing antimicrobial resistance |
-
2003
- 2003-02-14 US US10/367,361 patent/US20030181713A1/en not_active Abandoned
- 2003-02-17 IL IL16377803A patent/IL163778A0/xx unknown
- 2003-02-17 PL PL03370863A patent/PL370863A1/xx not_active Application Discontinuation
- 2003-02-17 CA CA002477729A patent/CA2477729A1/en not_active Abandoned
- 2003-02-17 KR KR10-2004-7013733A patent/KR20040094761A/ko not_active Application Discontinuation
- 2003-02-17 MX MXPA04008550A patent/MXPA04008550A/es not_active Application Discontinuation
- 2003-02-17 RU RU2004126699/04A patent/RU2004126699A/ru not_active Application Discontinuation
- 2003-02-17 EP EP03702894A patent/EP1483279A1/en not_active Withdrawn
- 2003-02-17 AU AU2003206011A patent/AU2003206011A1/en not_active Abandoned
- 2003-02-17 CN CNA03805177XA patent/CN1639182A/zh active Pending
- 2003-02-17 BR BR0308091-9A patent/BR0308091A/pt not_active Application Discontinuation
- 2003-02-17 WO PCT/IB2003/000595 patent/WO2003074541A1/en not_active Application Discontinuation
- 2003-02-27 PE PE2003000193A patent/PE20031002A1/es not_active Application Discontinuation
- 2003-02-27 PA PA20038567901A patent/PA8567901A1/es unknown
- 2003-02-28 UY UY27693A patent/UY27693A1/es not_active Application Discontinuation
- 2003-03-03 TW TW092104403A patent/TW200304826A/zh unknown
- 2003-03-03 AR ARP030100701A patent/AR038716A1/es not_active Application Discontinuation
- 2003-03-03 SV SV2003001491A patent/SV2004001491A/es not_active Application Discontinuation
- 2003-03-03 HN HN2003000082A patent/HN2003000082A/es unknown
- 2003-03-04 GT GT200300047A patent/GT200300047A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1483279A1 (en) | 2004-12-08 |
| UY27693A1 (es) | 2003-10-31 |
| PE20031002A1 (es) | 2003-11-29 |
| TW200304826A (en) | 2003-10-16 |
| IL163778A0 (en) | 2005-12-18 |
| US20030181713A1 (en) | 2003-09-25 |
| MXPA04008550A (es) | 2004-12-06 |
| HN2003000082A (es) | 2004-05-05 |
| SV2004001491A (es) | 2004-05-07 |
| GT200300047A (es) | 2003-10-10 |
| CA2477729A1 (en) | 2003-09-12 |
| WO2003074541A1 (en) | 2003-09-12 |
| PA8567901A1 (es) | 2003-11-12 |
| CN1639182A (zh) | 2005-07-13 |
| KR20040094761A (ko) | 2004-11-10 |
| AU2003206011A1 (en) | 2003-09-16 |
| BR0308091A (pt) | 2004-12-21 |
| PL370863A1 (en) | 2005-05-30 |
| RU2004126699A (ru) | 2005-04-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |