AR034771A1 - Formulacion vacunal potenciada por la combinacion de un adn con un antigeno - Google Patents
Formulacion vacunal potenciada por la combinacion de un adn con un antigenoInfo
- Publication number
- AR034771A1 AR034771A1 ARP020102614A AR034771A1 AR 034771 A1 AR034771 A1 AR 034771A1 AR P020102614 A ARP020102614 A AR P020102614A AR 034771 A1 AR034771 A1 AR 034771A1
- Authority
- AR
- Argentina
- Prior art keywords
- antigen
- components
- potentiated
- dna
- combination
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/29—Hepatitis virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/29—Hepatitis virus
- A61K39/292—Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Abstract
Formulación de antígenos vacunales, la cual contiene como componentes principales: a) uno o varios ADN que expresan una o varias proteínas en el individuo inmunizado y b) un antígeno viral en proporciones adecuadas. Un efecto potenciador ejerce al menos uno de los componentes sobre la respuesta inmune generada contra el otro. Nuevas formulaciones, minimizando el número de componentes que sean capaces de ampliar y potenciar el espectro de respuesta inmune contra diferentes entidades patogénicas (Virus Hepatitis B y Virus Hepatitis C) y de generar vacunas combinadas contra entidades patógenas. Estas formulaciones pueden ser aplicadas en la industria farmacéutica para uso profiláctico y/o terapéutico en humanos.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CU20010171A CU23244A1 (es) | 2001-07-16 | 2001-07-16 | Formulacion vacunal potenciada por la combinacion de un adn con un antigeno |
Publications (1)
Publication Number | Publication Date |
---|---|
AR034771A1 true AR034771A1 (es) | 2004-03-17 |
Family
ID=40091632
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP020102614 AR034771A1 (es) | 2001-07-16 | 2002-07-12 | Formulacion vacunal potenciada por la combinacion de un adn con un antigeno |
Country Status (16)
Country | Link |
---|---|
US (2) | US20040234543A1 (es) |
EP (1) | EP1417973B1 (es) |
JP (1) | JP4217611B2 (es) |
KR (1) | KR100905249B1 (es) |
CN (1) | CN1241644C (es) |
AR (1) | AR034771A1 (es) |
AU (1) | AU2002325783B2 (es) |
BR (1) | BR0211181A (es) |
CA (1) | CA2453260C (es) |
CU (1) | CU23244A1 (es) |
ES (1) | ES2393546T3 (es) |
MX (1) | MXPA04000431A (es) |
MY (1) | MY134885A (es) |
RU (1) | RU2294212C2 (es) |
WO (1) | WO2003007986A2 (es) |
ZA (1) | ZA200400286B (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CU23496A1 (es) * | 2004-09-03 | 2010-02-23 | Ct Ingenieria Genetica Biotech | Composición vacunal contra el virus de la hepatitis c |
EP1844142B1 (en) | 2005-01-20 | 2015-08-12 | Nature Technology Corporation | Vectors and methods for genetic immunization |
WO2008153733A2 (en) | 2007-05-29 | 2008-12-18 | Nature Technology Corporation | Vectors and methods for genetic immunization |
CN104830789A (zh) * | 2015-05-05 | 2015-08-12 | 杨光华 | 基于hcv1抗原的dc细胞、靶向性免疫细胞群及其制备方法和用途 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2239245B (en) * | 1989-12-18 | 1993-11-10 | Wellcome Found | Post-transfusional non-A non-B hepatitis viral polypeptides |
EP0461863A1 (en) * | 1990-06-12 | 1991-12-18 | Immuno Japan Inc. | Oligonucleotide primers, and their application for high-fidelity detection of non-A, non-B hepatitis virus |
US7070790B1 (en) * | 1993-06-29 | 2006-07-04 | The United States Of America As Represented By The Department Of Health And Human Services | Nucleotide and deduced amino acid sequences of the envelope 1 and core genes of isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines |
US6689757B1 (en) * | 1996-02-12 | 2004-02-10 | M.L. Laboratories Plc | Methods for vaccination and vaccines therefor |
CU22642A1 (es) * | 1996-12-12 | 2000-12-22 | Ct Ingenieria Genetica Biotech | Secuencia de adnc derivadas del genoma del virus de la hepatitis c y su uso |
CN1044092C (zh) * | 1997-02-26 | 1999-07-14 | 上海医科大学 | 抗原-抗体-重组dna复合型疫苗 |
FR2760367B1 (fr) * | 1997-03-06 | 1999-04-30 | Pasteur Merieux Serums Vacc | Composition vaccinale destinee a la prevention ou au traitement des hepatites c |
EP0980434B1 (en) * | 1997-05-06 | 2009-07-29 | Novartis Vaccines and Diagnostics, Inc. | Intracellular production of hepatitis c e2 truncated polypeptid |
US6153421A (en) * | 1997-07-18 | 2000-11-28 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Cloned genomes of infectious hepatitis C viruses and uses thereof |
GB9726555D0 (en) * | 1997-12-16 | 1998-02-11 | Smithkline Beecham Plc | Vaccine |
DE19915178A1 (de) * | 1999-04-03 | 2000-10-05 | Univ Mainz Johannes Gutenberg | Hepatitis C Virus Zellkultursystem |
DK1233782T3 (da) * | 1999-12-01 | 2009-02-09 | Novartis Vaccines & Diagnostic | Fremkaldelse af HCV-specifikke antistoffer |
-
2001
- 2001-07-16 CU CU20010171A patent/CU23244A1/es unknown
-
2002
- 2002-07-10 MY MYPI20022620A patent/MY134885A/en unknown
- 2002-07-12 ES ES02760072T patent/ES2393546T3/es not_active Expired - Lifetime
- 2002-07-12 MX MXPA04000431A patent/MXPA04000431A/es active IP Right Grant
- 2002-07-12 RU RU2004104357A patent/RU2294212C2/ru not_active IP Right Cessation
- 2002-07-12 CN CNB028142829A patent/CN1241644C/zh not_active Expired - Fee Related
- 2002-07-12 CA CA 2453260 patent/CA2453260C/en not_active Expired - Fee Related
- 2002-07-12 KR KR1020047000574A patent/KR100905249B1/ko not_active IP Right Cessation
- 2002-07-12 JP JP2003513591A patent/JP4217611B2/ja not_active Expired - Fee Related
- 2002-07-12 AU AU2002325783A patent/AU2002325783B2/en not_active Ceased
- 2002-07-12 AR ARP020102614 patent/AR034771A1/es not_active Application Discontinuation
- 2002-07-12 EP EP20020760072 patent/EP1417973B1/en not_active Expired - Lifetime
- 2002-07-12 US US10/484,112 patent/US20040234543A1/en not_active Abandoned
- 2002-07-12 BR BR0211181-0A patent/BR0211181A/pt not_active IP Right Cessation
- 2002-07-12 WO PCT/CU2002/000005 patent/WO2003007986A2/es active Application Filing
-
2004
- 2004-01-14 ZA ZA200400286A patent/ZA200400286B/en unknown
-
2009
- 2009-04-27 US US12/430,534 patent/US8691234B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP2004537552A (ja) | 2004-12-16 |
BR0211181A (pt) | 2004-08-10 |
EP1417973B1 (en) | 2012-08-29 |
ES2393546T3 (es) | 2012-12-26 |
KR100905249B1 (ko) | 2009-06-29 |
WO2003007986A8 (es) | 2004-04-29 |
CA2453260C (en) | 2013-03-19 |
CN1529616A (zh) | 2004-09-15 |
US8691234B2 (en) | 2014-04-08 |
RU2294212C2 (ru) | 2007-02-27 |
WO2003007986A2 (es) | 2003-01-30 |
AU2002325783B2 (en) | 2006-08-17 |
ZA200400286B (en) | 2004-10-04 |
MXPA04000431A (es) | 2004-03-18 |
CN1241644C (zh) | 2006-02-15 |
US20040234543A1 (en) | 2004-11-25 |
CU23244A1 (es) | 2007-10-17 |
US20100316669A1 (en) | 2010-12-16 |
EP1417973A2 (en) | 2004-05-12 |
JP4217611B2 (ja) | 2009-02-04 |
RU2004104357A (ru) | 2005-07-10 |
CA2453260A1 (en) | 2003-01-30 |
MY134885A (en) | 2007-12-31 |
WO2003007986A3 (es) | 2004-03-04 |
KR20040028924A (ko) | 2004-04-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant, registration | ||
FD | Application declared void or lapsed, e.g., due to non-payment of fee |